• Thumbnail for Gp41
    Gp41 also known as glycoprotein 41 is a subunit of the envelope protein complex of retroviruses, including human immunodeficiency virus (HIV). Gp41 is...
    14 KB (1,709 words) - 03:20, 12 March 2024
  • Thumbnail for HIV
    gp41 to penetrate the cell membrane. Repeat sequences in gp41, HR1, and HR2 then interact, causing the collapse of the extracellular portion of gp41 into...
    123 KB (14,115 words) - 13:33, 14 October 2024
  • glycoprotein (Env) of HIV, a trimer formed by heterodimers of gp120 and gp41. Env is responsible for binding to its primary host receptor, CD4, and its...
    33 KB (3,936 words) - 19:07, 2 September 2024
  • chemokine co-receptor CXCR4, another chemokine co-receptor found on CD4+ cells gp41, an HIV protein, closely associated with gp120, that penetrates the cell...
    9 KB (1,095 words) - 03:47, 25 December 2023
  • Thumbnail for Enfuvirtide
    needed] HIV binds to the host CD4+ cell receptor via the viral protein gp120; gp41, a viral transmembrane protein, then undergoes a conformational change that...
    12 KB (820 words) - 06:03, 18 March 2024
  • Env (gene) (section gp41)
    and is cleaved into gp120 and gp41 by the host cell protease, furin. To form an active fusion protein, SU gp120 and TM gp41 polypeptides remain non-covalently...
    17 KB (2,253 words) - 14:23, 3 December 2023
  • gp120 is closely associated with a trimer of gp41 via van der Waals interactions. Eventually, the gp41 N-terminal fusion peptide sequence anchors into...
    34 KB (3,860 words) - 13:37, 5 October 2024
  • Thumbnail for Envelope glycoprotein GP120
    CD4 induces the start of a cascade of conformational changes in gp120 and gp41 that lead to the fusion of the viral membrane with the host cell membrane...
    21 KB (2,547 words) - 00:52, 4 December 2023
  • cells express a CD4 receptor, to which HIV can bind, through the gp120 and gp41 proteins on its surface. HIV also requires a second co-receptor along with...
    21 KB (2,537 words) - 07:13, 13 August 2024
  • epitopes, on Env or on Env's subunits (gp120 or gp41). Instead, they attach to parts of both. Gp120 and gp41 assemble as a trimer. The bNAbs binding site...
    8 KB (870 words) - 11:42, 22 August 2024
  • Thumbnail for Glycoprotein
    bind to inorganic substances, such as calcium in bone. Glycoprotein-41 (gp41) and glycoprotein-120 (gp120) are HIV viral coat proteins. Soluble glycoproteins...
    28 KB (2,653 words) - 04:14, 23 July 2024
  • Thumbnail for CCR5
    precursor encoded for by the HIV-1 env gene: the Gp120 external subunit and the Gp41 transmembrane subunit. This envelope glycoprotein structure is arranged into...
    67 KB (7,850 words) - 21:49, 1 November 2024
  • Thumbnail for HIV vaccine development
    region called glycoprotein 120 (gp120) and a stem called glycoprotein 41 (gp41) that anchors Env in the viral membrane. Only the functional portions of...
    48 KB (5,624 words) - 02:16, 4 September 2024
  • envelope protein SU, encoded by the viral gene env. 120000 Da (daltons). Gp41 transmembrane envelope protein TM, also encoded by the viral gene env. 41000...
    16 KB (1,770 words) - 20:38, 20 September 2024
  • kill the infected T helper cell. However, if T helper cells are nearby, the gp41 HIV receptors displayed on the surface of the T helper cell will bind to...
    18 KB (2,046 words) - 03:47, 22 August 2024
  • Thumbnail for Membrane fusion protein
    I Filoviridae Zaire-, Sudan- ebolaviruses, Marburgvirus Glycoprotein 41 Gp41 I Retroviridae HIV Hemagglutinin H, HA, HN I Orthomyxoviridae, Paramyxoviridae...
    11 KB (1,132 words) - 18:32, 24 September 2024
  • Thumbnail for CD4
    receptors CCR5 or CXCR4. Following a structural change in another viral protein (gp41), HIV inserts a fusion peptide into the host cell that allows the outer membrane...
    22 KB (2,581 words) - 20:03, 21 June 2024
  • Thumbnail for Spike protein
    peplomers.: 318–25  These are protein complexes formed by two proteins, gp41 and gp120, both expressed from the env gene, collectively forming a spike...
    11 KB (1,091 words) - 15:33, 5 September 2024
  • Thumbnail for VIR-576
    VIR-576 is synthetic peptide that binds to HIV-1's hydrophobic fusion peptide gp41, preventing the virus from inserting itself into a host cell's membrane to...
    17 KB (1,628 words) - 01:05, 25 September 2024
  • Thumbnail for Toll-like receptor 10
    recent studies have identified ligands for TLR10 and these include HIV-gp41. Ligands for TLR2 are potential ligands for TLR10. The protein encoded by...
    6 KB (823 words) - 00:42, 27 October 2024
  • protein (a trimer composed of gp120 and gp41 subunits). These site include the CD4 binding site or the gp41-gp120 interface. Los Alamos National Laboratory's...
    32 KB (3,494 words) - 00:52, 30 July 2024
  • recognizes an epitope in the membrane-proximal external region (MPER) of HIV-1 gp41. 2F5 then binds to this epitope and its constant region interacts with the...
    13 KB (1,646 words) - 06:28, 27 November 2023
  • be injected and acts by interacting with the N-terminal heptad repeat of gp41 of HIV to form an inactive hetero six-helix bundle, therefore preventing...
    133 KB (15,784 words) - 05:42, 17 September 2024
  • Thumbnail for Viral protein
    M2 protein in the influenza virus gp160, composed of subunits gp120 and gp41, in the human immunodeficiency virus (HIV). Viral glycoproteins play a critical...
    14 KB (1,673 words) - 01:24, 21 April 2024
  • Thumbnail for Helicase
    Croquette V (December 2007). "Real-time observation of bacteriophage T4 gp41 helicase reveals an unwinding mechanism". Proceedings of the National Academy...
    56 KB (6,916 words) - 17:01, 27 August 2024
  • GQ34 — April 7, 2003 Kitt Peak Spacewatch  · 3.0 km MPC · JPL 350992 2003 GP41 — April 9, 2003 Kitt Peak Spacewatch  · 3.1 km MPC · JPL 350993 2003 GH42...
    185 KB (301 words) - 16:53, 30 November 2023
  • Thumbnail for HLA-DQA2
    1994). "HIV-1 gp41 binding proteins and antibodies to gp41 could inhibit enhancement of human Raji cell MHC class I and II expression by gp41". Molecular...
    10 KB (1,251 words) - 06:48, 11 July 2024
  • Thumbnail for Coronavirus spike protein
    include the coronavirus spike protein, influenza virus hemagglutinin, and HIV Gp41, are thought to be evolutionarily related. The S2 region of the spike protein...
    76 KB (7,457 words) - 07:06, 3 October 2024
  • Thumbnail for Furin
    proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly. This protease is also thought to play a role in...
    17 KB (2,288 words) - 15:22, 19 March 2024
  • globulins – glycoprotein – gonorrhea – gp120 (gp120) – gp160 (gp160) – gp41 (gp41) – granulocyte – granulocyte macrophage-colony stimulating factor (GM-CSF)...
    23 KB (1,720 words) - 22:45, 3 January 2023