• Graft-versus-tumor effect (GvT) appears after allogeneic hematopoietic stem cell transplantation (HSCT). The graft contains donor T cells (T lymphocytes)...
    9 KB (1,116 words) - 17:21, 7 November 2023
  • Thumbnail for Graft-versus-host disease
    Graft-versus-host disease (GvHD) is a syndrome, characterized by inflammation in different organs. GvHD is commonly associated with bone marrow transplants...
    39 KB (4,442 words) - 15:41, 17 October 2024
  • Thumbnail for Hematopoietic stem cell transplantation
    remaining recipient HSCs and to induce the graft-versus-tumor effect. This effect is often accompanied by mild graft-versus-host disease, the appearance of which...
    73 KB (8,333 words) - 21:39, 14 November 2024
  • Thumbnail for Transplant rejection
    allograft rejection via the CD4 and CD8 T cells. Graft-versus-host disease Graft-versus-tumor effect Immunosuppression Transplant engineering Frohn C...
    29 KB (3,272 words) - 23:54, 28 May 2024
  • Thumbnail for Bone grafting
    trauma or malignant tumor invasion. The periosteum and nutrient artery are generally removed with the piece of bone so that the graft will remain alive...
    33 KB (4,044 words) - 08:16, 20 November 2024
  • Thumbnail for Nancy Flournoy
    statistics to bone marrow transplantation, and in particular on the graft-versus-tumor effect. She is Curators' Distinguished Professor Emeritus of Statistics...
    11 KB (1,030 words) - 19:05, 15 October 2024
  • called the graft-versus-tumor effect (GVT). The donor T-cells can attack and control the growth of residual cancer cells providing the GVT effect. It is hoped...
    3 KB (364 words) - 16:34, 6 February 2022
  • a Brazilian television channel Glyn Valley Tramway in Wales Graft-versus-tumor effect in transplantation medicine Grand Valley Trail, in Ontario, Canada...
    850 bytes (133 words) - 01:23, 14 July 2024
  • Thumbnail for Cancer treatment
    the donor's immune cells will often attack the tumor in a phenomenon known as graft-versus-tumor effect. For this reason, allogeneic HSCT leads to a higher...
    70 KB (8,435 words) - 06:51, 19 October 2024
  • molecules (such as hormones or cytokines) by tumor cells or by an immune response against the tumor. Unlike a mass effect, it is not due to the local presence...
    28 KB (2,358 words) - 16:27, 5 March 2024
  • immune system of the transplanted individual and a decreased Graft-versus-tumor effect. This problem is partially answered by more selective depletion...
    24 KB (2,830 words) - 09:15, 19 March 2024
  • Thumbnail for Minor histocompatibility antigen
    selectively on leukemic cells in order to destroy these tumor cells referred to as graft-versus- leukemia effect (GVL). The recognition of a mature T cell to this...
    18 KB (1,681 words) - 12:56, 18 August 2023
  • known for the design of adaptive clinical trials and for the graft-versus-tumor effect in bone marrow transplants Emily B. Fox, American statistician...
    70 KB (8,445 words) - 22:48, 29 September 2024
  • Freund's adjuvant Gc-MAF Gluten immunochemistry Glycoprotein 130 Graft versus tumor effect Granulocyte colony-stimulating factor Granulocyte colony-stimulating...
    13 KB (1,237 words) - 01:24, 15 January 2024
  • TLR5 agonist enhances CD8(+) T cell-mediated graft-versus-tumor effect without exacerbating graft-versus-host disease". Journal of Immunology. 189 (10):...
    10 KB (1,044 words) - 11:51, 8 November 2023
  • Thumbnail for Cyclophosphamide
    melphalan in people who are ill-suited for autologous stem cell transplant. Graft-versus-host disease (GVHD) is a major barrier for allogeneic stem cell transplant...
    39 KB (3,990 words) - 18:36, 16 October 2024
  • involved the detrimental effects of renal fibrosis.[citation needed] Graft-versus-host disease (GvHD) targets JAK 1 and 2, the human tyrosine kinase protein...
    20 KB (2,259 words) - 08:57, 2 November 2024
  • Thumbnail for Sirolimus
    DA (June 1998). "Rapamycin inhibits the generation of graft-versus-host disease- and graft-versus-leukemia-causing T cells by interfering with the production...
    70 KB (7,051 words) - 03:41, 9 November 2024
  • Thumbnail for Natural killer cell
    cells be removed before infusion into the patients to remove the risk of graft versus host disease, which can be fatal. This can be achieved using an immunomagnetic...
    75 KB (9,227 words) - 23:32, 16 October 2024
  • Thumbnail for Microchimerism
    Horowitz, MH (1 March 2002). "Effect of tolerance to noninherited maternal antigens on the occurrence of graft-versus-host disease after bone marrow...
    43 KB (5,117 words) - 18:16, 17 October 2024
  • Thumbnail for Liver transplantation
    fever, slight increase in white blood count and graft-site tenderness.[citation needed] Three types of graft rejection may occur: hyperacute rejection, acute...
    61 KB (6,809 words) - 14:22, 10 November 2024
  • Thumbnail for Thalidomide
    medication used to treat a number of cancers (e.g., multiple myeloma), graft-versus-host disease, and many skin disorders (e.g., complications of leprosy...
    76 KB (7,432 words) - 14:59, 21 November 2024
  • Thumbnail for Immunosuppressive drug
    posttransplantory immunosuppressants to prevent the acute transplant rejection and graft-versus-host disease. Nevertheless, they do not prevent an infection and also...
    29 KB (3,378 words) - 02:54, 25 September 2024
  • Thumbnail for Lymphoma
    prophylaxis of graft-versus-host diseases. The evidence is very uncertain about the therapeutic effect of mesenchymal stromal cells to treat graft-versus-host diseases...
    67 KB (6,603 words) - 19:22, 22 November 2024
  • Thumbnail for Ibrutinib
    Waldenström's macroglobulinemia (WM), marginal zone lymphoma (MZL), and chronic graft versus host disease (cGVHD). Very common (>10% frequency) adverse effects include...
    29 KB (2,605 words) - 21:22, 16 August 2024
  • Thumbnail for Cellular adoptive immunotherapy
    and cancer's anti-tumour effect may vary. For example, the T- cells may not be activated and sustain the anti-tumor effect long enough, or the number...
    19 KB (2,170 words) - 03:58, 19 September 2024
  • Thumbnail for Cancer immunotherapy
    The major advantage of this approach is that these cells do not cause graft-versus-host disease. The disadvantage is that transferred cells frequently have...
    92 KB (12,517 words) - 05:38, 1 October 2024
  • Thumbnail for Mastocytoma in dogs
    skin defect, so skin grafting may also be necessary. Biopsies should be taken from the margins and the remaining tissue in depth (tumor bed) to check for...
    44 KB (5,640 words) - 16:03, 25 April 2024
  • Cushing's syndrome. Pharmacology has little effect and therefore surgery is the best option. Removal of the tumor results in an 80%-90% cure rate. A neuroradiologist...
    28 KB (3,611 words) - 14:52, 25 May 2024
  • the graft-versus-tumor effect through posttransplant immunization with granulocyte-macrophage colony-stimulating factor (GM-CSF)-producing tumor vaccines...
    11 KB (1,436 words) - 20:30, 18 January 2022