Graft-versus-tumor effect (GvT) appears after allogeneic hematopoietic stem cell transplantation (HSCT). The graft contains donor T cells (T lymphocytes)...
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Graft-versus-host disease (GvHD) is a syndrome, characterized by inflammation in different organs. GvHD is commonly associated with bone marrow transplants...
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Hematopoietic stem cell transplantation (redirect from Graft versus tumor)
remaining recipient HSCs and to induce the graft-versus-tumor effect. This effect is often accompanied by mild graft-versus-host disease, the appearance of which...
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Transplant rejection (redirect from Host-versus-graft disease)
allograft rejection via the CD4 and CD8 T cells. Graft-versus-host disease Graft-versus-tumor effect Immunosuppression Transplant engineering Frohn C...
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trauma or malignant tumor invasion. The periosteum and nutrient artery are generally removed with the piece of bone so that the graft will remain alive...
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statistics to bone marrow transplantation, and in particular on the graft-versus-tumor effect. She is Curators' Distinguished Professor Emeritus of Statistics...
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called the graft-versus-tumor effect (GVT). The donor T-cells can attack and control the growth of residual cancer cells providing the GVT effect. It is hoped...
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a Brazilian television channel Glyn Valley Tramway in Wales Graft-versus-tumor effect in transplantation medicine Grand Valley Trail, in Ontario, Canada...
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the donor's immune cells will often attack the tumor in a phenomenon known as graft-versus-tumor effect. For this reason, allogeneic HSCT leads to a higher...
70 KB (8,435 words) - 06:51, 19 October 2024
molecules (such as hormones or cytokines) by tumor cells or by an immune response against the tumor. Unlike a mass effect, it is not due to the local presence...
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immune system of the transplanted individual and a decreased Graft-versus-tumor effect. This problem is partially answered by more selective depletion...
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selectively on leukemic cells in order to destroy these tumor cells referred to as graft-versus- leukemia effect (GVL). The recognition of a mature T cell to this...
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known for the design of adaptive clinical trials and for the graft-versus-tumor effect in bone marrow transplants Emily B. Fox, American statistician...
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Freund's adjuvant Gc-MAF Gluten immunochemistry Glycoprotein 130 Graft versus tumor effect Granulocyte colony-stimulating factor Granulocyte colony-stimulating...
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TLR5 agonist enhances CD8(+) T cell-mediated graft-versus-tumor effect without exacerbating graft-versus-host disease". Journal of Immunology. 189 (10):...
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Cyclophosphamide (section Graft-versus-host disease)
melphalan in people who are ill-suited for autologous stem cell transplant. Graft-versus-host disease (GVHD) is a major barrier for allogeneic stem cell transplant...
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Inflammatory cytokine (section Graft-vs-host disease)
involved the detrimental effects of renal fibrosis.[citation needed] Graft-versus-host disease (GvHD) targets JAK 1 and 2, the human tyrosine kinase protein...
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Sirolimus (section Graft-versus-host disease)
DA (June 1998). "Rapamycin inhibits the generation of graft-versus-host disease- and graft-versus-leukemia-causing T cells by interfering with the production...
70 KB (7,051 words) - 03:41, 9 November 2024
Natural killer cell (section Tumor cell surveillance)
cells be removed before infusion into the patients to remove the risk of graft versus host disease, which can be fatal. This can be achieved using an immunomagnetic...
75 KB (9,227 words) - 23:32, 16 October 2024
Horowitz, MH (1 March 2002). "Effect of tolerance to noninherited maternal antigens on the occurrence of graft-versus-host disease after bone marrow...
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Liver transplantation (section Graft rejection)
fever, slight increase in white blood count and graft-site tenderness.[citation needed] Three types of graft rejection may occur: hyperacute rejection, acute...
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medication used to treat a number of cancers (e.g., multiple myeloma), graft-versus-host disease, and many skin disorders (e.g., complications of leprosy...
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posttransplantory immunosuppressants to prevent the acute transplant rejection and graft-versus-host disease. Nevertheless, they do not prevent an infection and also...
29 KB (3,378 words) - 02:54, 25 September 2024
prophylaxis of graft-versus-host diseases. The evidence is very uncertain about the therapeutic effect of mesenchymal stromal cells to treat graft-versus-host diseases...
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Waldenström's macroglobulinemia (WM), marginal zone lymphoma (MZL), and chronic graft versus host disease (cGVHD). Very common (>10% frequency) adverse effects include...
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and cancer's anti-tumour effect may vary. For example, the T- cells may not be activated and sustain the anti-tumor effect long enough, or the number...
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Cancer immunotherapy (redirect from Tumor immunotherapy)
The major advantage of this approach is that these cells do not cause graft-versus-host disease. The disadvantage is that transferred cells frequently have...
92 KB (12,517 words) - 05:38, 1 October 2024
Mastocytoma in dogs (redirect from Mast cell tumor of the dog)
skin defect, so skin grafting may also be necessary. Biopsies should be taken from the margins and the remaining tissue in depth (tumor bed) to check for...
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Cushing's syndrome. Pharmacology has little effect and therefore surgery is the best option. Removal of the tumor results in an 80%-90% cure rate. A neuroradiologist...
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the graft-versus-tumor effect through posttransplant immunization with granulocyte-macrophage colony-stimulating factor (GM-CSF)-producing tumor vaccines...
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