Guanylate cyclase (EC 4.6.1.2, also known as guanyl cyclase, guanylyl cyclase, or GC; systematic name GTP diphosphate-lyase (cyclizing; 3′,5′-cyclic-GMP-forming))...

guanylate cyclase activator (or "GUCA") is a member of a group of proteins that upregulate guanylate cyclase. GUCA is also known as guanylate cyclase-activating...

Guanylate cyclase activator 2B is a protein that in humans is encoded by the GUCA2B gene. This gene encodes a preproprotein that is proteolytically processed...

Mitrovic V, Mebazaa A (January 2013). "Cinaciguat, a soluble guanylate cyclase activator, unloads the heart but also causes hypotension in acute decompensated...

Guanylate cyclase 2C, also known as guanylyl cyclase C (GC-C), intestinal guanylate cyclase, guanylate cyclase-C receptor, or the heat-stable enterotoxin...

Adempas, is a medication by Bayer that is a stimulator of soluble guanylate cyclase (sGC). It is used to treat two forms of pulmonary hypertension (PH):...

decompensation event. It is taken by mouth. Vericiguat is a soluble guanylate cyclase (sGC) stimulator. Common side effects include low blood pressure and...

Soluble guanylate cyclase (sGC) stimulators are a class of drugs developed to treat heart failure, pulmonary hypertension, and other diseases. The first-in-class...

et al. (February 1991). "Recoverin: a calcium sensitive activator of retinal rod guanylate cyclase". Science. 251 (4996): 915–918. Bibcode:1991Sci...251...

muscle by binding to the heme moiety of cytosolic guanylate cyclase, activating guanylate cyclase and increasing intracellular levels of cyclic-guanosine...

from its bound calcium ions, and interacts with Guanylate Cyclase, activating it. Guanylate Cyclase then proceeds to transform GTP to cGMP, replenishing...

Adenylate cyclase (EC 4.6.1.1, also commonly known as adenyl cyclase and adenylyl cyclase, abbreviated AC) is an enzyme with systematic name ATP diphosphate-lyase...

Guanylyl cyclase-activating protein 2 is an enzyme that in humans is encoded by the GUCA1B gene. Alternative names: Guanylate cyclase activator 1B Retinal...

Capoeira Angola Pelourinho, Capoeira group by Mestre Moraes Guanylate cyclase-activating protein Vancouver's greenest city action plan, an urban sustainability...

Guanylate cyclase (GC) catalyzes cGMP synthesis. This enzyme converts GTP to cGMP. Peptide hormones such as the atrial natriuretic factor activate membrane-bound...

Avenciguat (development name BI 685509) is a soluble guanylate cyclase activator developed by Boehringer Ingelheim for kidney disease, and cirrhosis....

Guanylate cyclase-coupled receptors or Membrane-bound guanylyl cyclases are single-pass transmembrane proteins. Guanylate cyclase-coupled receptor on...

(OQM Div, MSN Laboratories, India). Plecanatide is an agonist of guanylate cyclase-C. Plecanatide increases intestinal transit and fluid through a buildup...

Warren MJ, Bird AC, Bhattacharya SS (Mar 1998). "A mutation in guanylate cyclase activator 1A (GUCA1A) in an autosomal dominant cone dystrophy pedigree...

Mosliciguat (BAY 1237592) is an inhaled soluble guanylate cyclase activator developed by Bayer for pulmonary arterial hypertension. El-Kersh, Karim; Jalil...

Sandner, Peter (December 2021). "Runcaciguat, a novel soluble guanylate cyclase activator, shows renoprotection in hypertensive, diabetic, and metabolic...

KL, Smith CE (February 1992). "Guanylin: an endogenous activator of intestinal guanylate cyclase". Proceedings of the National Academy of Sciences of the...

G protein nucleolar 2 GSTM1 (1p13) GUCA2B: encoding protein Guanylate cyclase activator 2B HDAC1 (1p35) HES2: Hes family bHLH transcription factor 2...

Guanosine triphosphate ↔ 2 diphosphate + cyclic di-3',5'-guanylate The substrates of diguanylate cyclases (DGCs) are two molecules of guanosine triphosphate...

Retinal guanylyl cyclase 1 also known as guanylate cyclase 2D, retinal is an enzyme that in humans is encoded by the GUCY2D (guanylate cyclase 2D) gene. This...

guanylate cyclase, leading to increased formation of cyclic guanosine monophosphate (cGMP) from guanosine triphosphate (GTP). The cGMP then activates...

Secondary messenger systems can be synthesized and activated by enzymes, for example, the cyclases that synthesize cyclic nucleotides, or by opening of...

M.P. (1994). "Purification and physiological evaluation of a guanylate cyclase activating protein from retinal rods". Proceedings of the National Academy...

small intestine. Guanylin acts as an agonist of the guanylyl cyclase receptor guanylate cyclase 2C (GC-C), and regulates electrolyte and water transport in...

in cyclic GMP levels in brain and liver with sodium azide an activator of guanylate cyclase". Nature. 257 (5528): 700–702. Bibcode:1975Natur.257..700K....