• variants of HEK 293 have been reported. HEK 293 HEK 293F HEK 293FT HEK 293T HEK 293S HEK 293FTM HEK 293SG HEK 293SGGD HEK 293H HEK 293E HEK EBNA1-6E HEK 293MSR...
    25 KB (3,064 words) - 08:30, 25 March 2025
  • Thumbnail for Immortalised cell line
    cycle (e.g., the adenovirus type 5 E1 gene was used to immortalise the HEK 293 cell line; the Epstein–Barr virus can immortalise B lymphocytes by infection)...
    10 KB (1,139 words) - 17:57, 26 November 2024
  • Thumbnail for Sputnik V COVID-19 vaccine
    outside the HEK 293 cells. For the production of the vaccine, to propagate adenoviral vectors in which the E1 gene was deleted, HEK 293 cells are used...
    154 KB (13,917 words) - 17:09, 10 March 2025
  • Thumbnail for Cell culture
    American Journal of Physiology. Gastrointestinal and Liver Physiology. 293 (6): G1147 – G1154. doi:10.1152/ajpgi.00032.2007. PMID 17932231. S2CID 201357...
    108 KB (8,466 words) - 10:22, 15 December 2024
  • the cell lines HEK-293 or PER.C6 for production. In other cases, notably the vaccines made by Pfizer, Sputnik-V and Moderna, HEK-293 was used during...
    15 KB (1,549 words) - 11:23, 5 January 2025
  • Thumbnail for Lex van der Eb
    the technique of calcium phosphate transfection and the founding of the HEK 293 and PER.C6 cell lines. Van der Eb was born on 16 January 1934 in Bandung...
    14 KB (1,256 words) - 03:28, 29 June 2024
  • Thumbnail for MRC-5
    genetically normal human cell." The manufacturing of the vaccine used the HEK 293 fetal cell line, the kidney cells of an aborted or spontaneously miscarried...
    3 KB (330 words) - 10:08, 3 February 2025
  • Thumbnail for TRPV1
    neurons, expressed the clones in HEK 293 cells, and looked for cells that respond to capsaicin with calcium influx (which HEK-293 normally do not). After several...
    57 KB (6,738 words) - 18:37, 29 March 2025
  • Thumbnail for Iodoresiniferatoxin
    dependent upon temperature and pH value, as has been shown in research with HEK 293 cells expressing TRPV1. The optimal pH value is around 7.8 to 8.0 and binding...
    9 KB (774 words) - 09:56, 17 January 2025
  • Thumbnail for Multiple cloning site
    "Purification and characterization of a bioactive alpha-fetoprotein produced by HEK-293 cells". Protein Expression and Purification. 136: 1–6. doi:10.1016/j.pep...
    34 KB (3,838 words) - 08:51, 9 April 2025
  • Thumbnail for Protein production
    kidney (HEK) cells. Chinese hamster ovary cell Mouse myeloma lymphoblstoid (e.g. NS0 cell) Fully Human Human embryonic kidney cells (HEK-293) Human embryonic...
    25 KB (2,654 words) - 08:14, 28 October 2024
  • Thumbnail for Peroxisome
    Distribution of peroxisomes (white) in HEK 293 cells during mitosis...
    33 KB (3,858 words) - 07:49, 22 April 2025
  • Thumbnail for Riboswitch
    Transgene Cytotoxicity Increases Adeno-associated Virus Vector Yields in HEK-293 Cells". Molecular Therapy. 23 (10): 1582–1591. doi:10.1038/mt.2015.123...
    37 KB (3,938 words) - 17:53, 10 November 2024
  • Thumbnail for Itaconic acid
    leukotriene C4 and D4. Among a set of cultured human embryonic kidney HEK 293 cells made to express any one of 351 different human G protein-coupled...
    85 KB (10,196 words) - 00:04, 3 April 2025
  • Thumbnail for Small molecule sensors
    excellent metal ion selectivity are reported. In vitro experiments on HEK 293 cell culture were carried out using two-photon microscopy demonstrating...
    23 KB (2,557 words) - 03:43, 29 July 2024
  • point was in 2011, when Mader et al. developed a cell-based assay using HEK 293 cells which increased the detection rate of these antibodies in the serum...
    27 KB (2,799 words) - 09:09, 23 October 2024
  • Thumbnail for Epigenetics
    cytosines (epigenetic alterations) at these locations. Jiang et al. treated HEK 293 cells with agents causing oxidative DNA damage, (potassium bromate (KBrO3)...
    159 KB (18,196 words) - 01:58, 22 April 2025
  • Thumbnail for Memantine
    amino-alkyl-cyclohexanes antagonise 5-HT(3) receptor currents in cultured HEK-293 and N1E-115 cell systems in a non-competitive manner". Neuroscience Letters...
    67 KB (6,297 words) - 12:53, 20 April 2025
  • Thumbnail for Janssen COVID-19 vaccine
    the Russian Sputnik V COVID-19 vaccine which use human embryonic kidney (HEK) 293 cells for adenovirus vector replication. The Ad26 viral vector lacks the...
    141 KB (11,331 words) - 20:02, 8 April 2025
  • therapeutic efficacy of recombinant human interferon gamma, expressed in HEK 293 platform, was improved against drug-resistant ovarian cancer cell lines...
    29 KB (3,468 words) - 14:31, 20 March 2025
  • Thumbnail for BNIP3
    muscle cells, and adult rat cardiomyocytes. Using BNIP3 phosphomimetics in HEK 293 cells, researchers found that phosphorylation of BNIP3's C-terminus is...
    21 KB (2,693 words) - 19:41, 18 March 2025
  • proteins and regulate adenylyl cyclase in recombinant cell lines (CHO, HEK 293, SH-SY5Y). NPFF receptors are also coupled to voltage-gated N-type Ca2+...
    7 KB (801 words) - 07:14, 8 May 2024
  • Thumbnail for Insulin
    insulin release. Insulin is also used in many cell lines, such as CHO-s, HEK 293 or Sf9, for the manufacturing of monoclonal antibodies, virus vaccines...
    121 KB (13,818 words) - 19:59, 22 March 2025
  • also used including monkey cell lines pMK and Vero and human cell lines HEK 293, MRC 5, Per.C6, PMK, and WI-38. The candidate vaccine virus strain will...
    16 KB (1,533 words) - 02:48, 30 January 2023
  • Thumbnail for Monoamine releasing agent
    Kidney 293) cell line expressing DAT and SERT (IC50 and EC50 values are expressed in μM). [(Note: HEK293 cells lack TAAR1 expression: "HEK-293 cells do...
    262 KB (22,098 words) - 12:37, 30 March 2025
  • human RPE65 cDNA with a modified Kozak sequence. The virus is grown in HEK 293 cells and purified for administration. It was developed by Spark Therapeutics...
    14 KB (958 words) - 22:39, 19 February 2025
  • Thumbnail for Oxford–AstraZeneca COVID-19 vaccine
    deleted and replaced by a gene coding for the spike protein. However, the HEK 293 cells used for vaccine manufacturing, express several adenoviral genes...
    214 KB (17,125 words) - 14:52, 17 March 2025
  • Thumbnail for DNA repair
    cytosines (epigenetic alterations) at these locations. Jiang et al. treated HEK 293 cells with agents causing oxidative DNA damage, (potassium bromate (KBrO3)...
    132 KB (16,176 words) - 11:20, 23 April 2025
  • Thumbnail for Halostachine
    receptors. Using a β2 adrenergic receptor preparation derived from transfected HEK 293 cells, Liappakis and co-workers found that in wild-type receptors, racemic...
    17 KB (2,152 words) - 23:57, 2 July 2024
  • order to trigger a signalling cascade. For example, it has been shown that HEK 293 cells co-transfected with human mannose receptor and human Toll-like receptor...
    32 KB (3,688 words) - 06:43, 3 June 2024