• Haptens (derived from the Greek haptein, meaning “to fasten”) are small molecules that elicit an immune response only when attached to a large carrier...
    21 KB (2,512 words) - 07:32, 5 April 2024
  • hapten. Haptens are low-molecular-weight compounds that may be bound by antibodies, but cannot elicit an immune response. Consequently, the haptens themselves...
    7 KB (826 words) - 03:24, 24 November 2023
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    lysine residues for coupling haptens allows a high hapten:carrier protein ratio, increasing the likelihood of generating hapten-specific antibodies. In addition...
    10 KB (1,213 words) - 03:13, 23 November 2023
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    [3.2.1] octane-2-carboxamido-hexanoic acid Cocaine haptens that create catalytic anti-bodies require transitional states as affected...
    111 KB (5,555 words) - 16:59, 8 June 2024
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    Instead, it attaches to certain proteins of the skin, where it acts as a hapten, leading to a type IV hypersensitivity reaction.[self-published source?]...
    19 KB (2,036 words) - 14:50, 14 June 2024
  • compound lacked hapten characteristics, a hapten feature of a drug metabolite as cause for the DHR was postulated. Importantly, the hapten theory as explanation...
    30 KB (4,156 words) - 03:57, 3 December 2023
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    oak, or poison sumac. Urushiol, which is not itself a protein, acts as a hapten and chemically reacts with, binds to, and changes the shape of integral...
    108 KB (10,742 words) - 11:31, 7 July 2024
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    hybridization to mRNA with oligonucleotide and RNA probes (both radio-labeled and hapten-labeled), analysis with light and electron microscopes, whole mount in situ...
    12 KB (1,319 words) - 10:37, 9 July 2024
  • Antigenicity is the capacity of a chemical structure (either an antigen or hapten) to bind specifically with a group of certain products that have adaptive...
    16 KB (1,812 words) - 23:41, 1 January 2024
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    water-soluble analog, Sulfo-SMCC, is commonly used to prepare antibody-hapten conjugates for antibody development. An in-vitro cross-linking method is...
    18 KB (1,796 words) - 01:06, 19 July 2024
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    discriminate among specific epitopes present on the antigen surface. A hapten is a small molecule that can only induce an immune response when attached...
    20 KB (2,435 words) - 08:54, 4 March 2024
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    Kalish, J. A. Wood & A. LaPorte (1994). "Processing of urushiol (poison ivy) hapten by both endogenous and exogenous pathways for presentation to T cells in...
    16 KB (1,580 words) - 23:41, 3 July 2024
  • new members were recruited: Christoffer Nilsson to play drums and Annika Haptén, a singer. Later that summer, Staffan Franzén was officially announced as...
    12 KB (979 words) - 10:54, 26 May 2024
  • [citation needed] There are two models for this: the hapten model and the autoantibody model. The hapten model proposes that certain drugs, especially penicillin...
    7 KB (796 words) - 07:10, 6 July 2024
  • containing two nitro functional groups attached to a phenyl ring. It is a hapten used in vaccine preparation. Dinitrophenyl does not elicit any immune response...
    1 KB (130 words) - 10:34, 10 March 2021
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    from the U.S. National Institute on Drug Abuse. NicVAX consists of the hapten 3'-aminomethylnicotine which has been conjugated (attached) to Pseudomonas...
    266 KB (31,198 words) - 22:24, 18 July 2024
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    This is a known allergen that becomes bound to plasma proteins, creating a hapten-protein complex – a signature mechanism in true IgE drug allergy and true...
    28 KB (3,269 words) - 19:12, 13 April 2024
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    NicVAX, which aims to vaccinate against nicotine using a chemically modified hapten version linked to exotoxin A TA-CD, cocaine linked to inactivated cholera...
    10 KB (1,108 words) - 13:43, 27 May 2024
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    large molecules found on the surfaces of pathogens, but can also be small haptens (such as penicillin) attached to carrier molecule. Each lineage of B cell...
    118 KB (13,493 words) - 15:10, 22 June 2024
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    molecule has been associated with two significance adverse effects: the hapten or immune response. This immune response, also known as agranulocytosis...
    22 KB (2,241 words) - 16:50, 29 June 2024
  • Guanche language Guidance, navigation, and control, in aeronautics A cocaine hapten analog This disambiguation page lists articles associated with the title...
    1 KB (188 words) - 19:16, 11 December 2022
  • isotope labeling, and tagging the base with a hapten and detecting chromogenically with an anti-hapten antibody-enzyme conjugate (e.g., via an ELISA format)...
    2 KB (252 words) - 15:32, 17 December 2021
  • cross-linking of biopolymers, or chemical attachment of unnatural substituents (haptens) to biopolymers.[citation needed] Under normal aerobic conditions, approximately...
    58 KB (7,162 words) - 04:05, 22 July 2024
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    Weizmann Institute of Science Thesis Kinetic and thermodynamic studies of hapten induced conformational changes in immunoglobulins  (1978) Academic advisors...
    4 KB (201 words) - 12:38, 8 May 2024
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    Gul, and Mohammad Khalid Ashfaq. Work on the compound is ongoing under Hapten Sciences, who licensed the university's research in 2010. The compound has...
    6 KB (358 words) - 00:37, 14 May 2023
  • diphtheria toxin, currently used as a carrier protein for polysaccharides and haptens to make them immunogenic. There is some dispute about the toxicity of CRM197...
    14 KB (1,507 words) - 18:21, 5 June 2024
  • binding fragment of polyclonal antibodies raised to Digitalis derivative as a hapten bound to a protein and is used for the reversal of life-threatening digoxin...
    18 KB (2,234 words) - 02:02, 12 July 2024
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    Trelawny bras? Mes ugens mil a dus Kernow A wodhvydh oll an kas. 'Medh aga Hapten, krev ha dreus, Gwas lowen ev a veu, "A pe Tour Loundres Karrek Loos, Ni...
    11 KB (983 words) - 21:27, 8 July 2024
  • Dextran 1 is a hapten inhibitor that greatly reduces the risk for anaphylactic reactions when administering dextran. Dextran 1 is composed of a small fraction...
    1 KB (145 words) - 14:25, 30 March 2023
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    different individuals, combine with epithelial-derived proteins, forming haptens which bind with Langerhans cells in the mucosa, which in turn present the...
    20 KB (2,032 words) - 04:55, 12 January 2024