• The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation. Different...
    59 KB (6,895 words) - 22:30, 25 April 2024
  • Thumbnail for Paracrine signaling
    cellular biology, paracrine signaling is a form of cell signaling, a type of cellular communication in which a cell produces a signal to induce changes in nearby...
    46 KB (4,967 words) - 21:12, 7 July 2024
  • Thumbnail for Sonic hedgehog protein
    Sonic hedgehog protein (SHH) is encoded for by the SHH gene. The protein is named after the video game character Sonic the Hedgehog. This signaling molecule...
    62 KB (7,249 words) - 16:46, 30 December 2024
  • A biochemical cascade, also known as a signaling cascade or signaling pathway, is a series of chemical reactions that occur within a biological cell when...
    99 KB (11,432 words) - 04:27, 2 November 2024
  • the activity of a component of the Hedgehog signaling pathway. Due to the role of aberrant Hedgehog signaling in tumor progression and cancer stem cell...
    27 KB (3,866 words) - 12:49, 22 August 2024
  • Patched (category Hedgehog signaling pathway)
    receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis...
    4 KB (442 words) - 03:03, 28 March 2022
  • Thumbnail for Smoothened
    Smoothened (category Hedgehog signaling pathway)
    (Class F) G protein-coupled receptor that is a component of the hedgehog signaling pathway and is conserved from flies to humans. It is the molecular target...
    28 KB (3,490 words) - 16:24, 17 March 2024
  • Thumbnail for Desert hedgehog (protein)
    Desert hedgehog, also Desert hedgehog homolog or Dhh, is a protein encoded by the DHH gene, and is a member of the hedgehog signaling pathway. The human...
    3 KB (381 words) - 20:29, 27 November 2024
  • Thumbnail for Indian hedgehog (protein)
    cell signaling protein is in the hedgehog signaling pathway. The several mammalian variants of the Drosophila hedgehog gene (which was the first named)...
    15 KB (1,856 words) - 08:54, 2 November 2024
  • anti-vehicle obstacle Hedgehog signaling pathway, a signal transduction pathway The Hedgehog, a 2009 French film directed by Mona Achache Hedgehog (EP), an EP by...
    1 KB (220 words) - 10:22, 7 October 2021
  • signalling pathway AMPK signalling pathway cAMP-dependent pathway Eph/ephrin signalling pathway Hedgehog signalling pathway Hippo signalling pathway Insulin...
    1,014 bytes (86 words) - 23:23, 19 January 2023
  • Thumbnail for Philip A. Beachy
    the roles of Hedgehog signaling in development, regeneration and cancer, discovered small molecules that could block the Hedgehog pathway, and advanced...
    15 KB (1,465 words) - 06:38, 3 January 2025
  • Ci protein (category Hedgehog signaling pathway)
    transcription factor involved in the Hedgehog signaling pathway. In the absence of a signal to the Hedgehog signaling pathway, the Ci protein is cleaved and...
    4 KB (446 words) - 17:13, 28 October 2022
  • cellular biology, the Wnt signaling pathways are a group of signal transduction pathways which begin with proteins that pass signals into a cell through cell...
    64 KB (7,432 words) - 08:21, 28 October 2024
  • Thumbnail for Vismodegib
    approval of vismodegib on January 30, 2012, represents the first Hedgehog signaling pathway targeting agent to gain U.S. Food and Drug Administration (FDA)...
    7 KB (483 words) - 19:42, 20 December 2023
  • Thumbnail for Sonidegib
    Odomzo, is a medication used to treat cancer. Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism). It was approved for medical...
    13 KB (1,058 words) - 01:41, 30 August 2024
  • Heywood Hill, a bookshop in London Hh, a signalling molecule in Drosophila named for the Hedgehog signaling pathway hh blood group, a rare blood type Henderson–Hasselbalch...
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  • particularly been noted in patients with a defect in the sonic hedgehog gene pathway and the disease formerly named CATCH22 for "cardiac anomaly, T-cell...
    13 KB (804 words) - 22:18, 16 December 2024
  • Thumbnail for Cyclopamine
    ingested by pregnant sheep. Cyclopamine interrupts the sonic hedgehog signalling pathway, instrumental in early development, ultimately causing birth...
    16 KB (1,441 words) - 13:23, 1 June 2024
  • Thumbnail for Gooseberry (gene)
    Gooseberry (gene) (category Hedgehog signaling pathway)
    Gooseberry is known for its interactions with key embryonic signaling pathways Wingless and Hedgehog. The gene also has clinical significance, being linked...
    17 KB (1,670 words) - 03:13, 15 September 2024
  • Thumbnail for Notch signaling pathway
    The Notch signaling pathway is a highly conserved cell signaling system present in most animals. Mammals possess four different notch receptors, referred...
    95 KB (11,025 words) - 08:58, 16 December 2024
  • Thumbnail for HHIP
    similar to the mouse hedgehog interacting protein, a regulatory component of the Hedgehog signaling pathway. Members of the hedgehog family are evolutionarily...
    4 KB (504 words) - 02:06, 1 December 2023
  • hedgehog, one of three proteins in a mammalian signaling pathway Sonic (disambiguation) Sonic the Hedgehog 2 (disambiguation) This disambiguation page lists...
    2 KB (260 words) - 04:03, 13 November 2024
  • Thumbnail for Purmorphamine
    agonist developed for the protein Smoothened, a key part of the hedgehog signaling pathway, which is involved in bone growth, cardiovascular regeneration...
    4 KB (303 words) - 21:27, 11 November 2023
  • Thumbnail for Itraconazole
    inhibitor in this class that has been shown to inhibit both the hedgehog signaling pathway and angiogenesis. These distinct activities are unrelated to inhibition...
    26 KB (2,478 words) - 00:18, 18 December 2024
  • JAK-STAT signaling pathway Imd pathway Localisation signal Oscillation Protein dynamics Systems biology Lipid signaling Redox signaling Signaling cascade...
    62 KB (6,781 words) - 02:39, 12 November 2024
  • Thumbnail for Nevoid basal-cell carcinoma syndrome
    that recognizes the Sonic Hedgehog ligand (SHH) and represses the Hedgehog (Hh) signaling pathway. The Hedgehog signaling pathway, which promotes cell proliferation...
    15 KB (1,730 words) - 17:39, 22 April 2024
  • Thumbnail for Tau-protein kinase
    participates in 14 metabolic pathways: erbb signaling pathway, cell cycle, wnt signaling pathway, hedgehog signaling pathway, axon guidance, focal adhesion...
    4 KB (404 words) - 15:58, 26 August 2023
  • Thumbnail for Brandt's hedgehog
    Abe, Yoshinori; Tanaka, Nobuyuki (2017-11-20). "Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer"...
    3 KB (332 words) - 02:33, 4 November 2024
  • parasegment by regulating the transmission of signals via the Wnt signaling pathway and Hedgehog signaling pathway. Segment polarity genes are expressed in...
    6 KB (691 words) - 12:31, 1 April 2024