• Thumbnail for Heparin
    Heparin, also known as unfractionated heparin (UFH), is a medication and naturally occurring glycosaminoglycan. Heparin is a blood anticoagulant that...
    78 KB (7,865 words) - 12:25, 1 July 2024
  • Thumbnail for Heparin-induced thrombocytopenia
    Heparin-induced thrombocytopenia (HIT) is the development of thrombocytopenia (a low platelet count), due to the administration of various forms of heparin...
    23 KB (2,552 words) - 17:15, 15 February 2024
  • Low-molecular-weight heparin (LMWH) is a class of anticoagulant medications. They are used in the prevention of blood clots and, in the treatment of venous...
    27 KB (3,060 words) - 19:12, 6 May 2024
  • Thumbnail for Anticoagulant
    aggregated platelet products. Common anticoagulants include warfarin and heparin. The use of anticoagulants is a decision based on the risks and benefits...
    78 KB (8,717 words) - 21:24, 13 July 2024
  • 2008 Chinese heparin adulteration, refers to heparin adulteration incidents that occurred in the United States of America in 2008. Pharmaceutical company...
    7 KB (767 words) - 18:27, 31 January 2024
  • Thumbnail for Heparan sulfate
    to heparin. Both consist of a variably sulfated repeating disaccharide unit. The main disaccharide units that occur in heparan sulfate and heparin are...
    36 KB (4,151 words) - 06:37, 27 May 2024
  • The enzyme heparin lyase (EC 4.2.2.7) catalyzes the following process: Eliminative cleavage of polysaccharides containing (1→4)-linked D-glucuronate or...
    1 KB (132 words) - 14:26, 26 August 2023
  • Thumbnail for Antithrombin
    β-antithrombin. Its activity is increased manyfold by the anticoagulant drug heparin, which enhances the binding of antithrombin to factor IIa (thrombin) and...
    45 KB (5,331 words) - 23:48, 9 March 2024
  • effects of heparin. It is specifically used in heparin overdose, in low molecular weight heparin overdose, and to reverse the effects of heparin during delivery...
    14 KB (1,419 words) - 18:49, 28 June 2024
  • Thumbnail for Oxygenator
    uncoated CPB circuits require a high dose of systemic heparin. Although the effects of heparin are reversible by administering protamine, there are a...
    9 KB (1,145 words) - 06:07, 26 November 2023
  • others between May and December, 2006. He killed with a hidden vial of heparin — a blood-thinning drug causing internal bleeding when administered in...
    2 KB (157 words) - 18:42, 25 June 2024
  • Thumbnail for Heparin-binding EGF-like growth factor
    Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of proteins that in humans is encoded by the HBEGF gene. HB-EGF-like growth...
    20 KB (2,598 words) - 16:38, 26 June 2024
  • Thumbnail for Enoxaparin sodium
    Enoxaparin sodium (category Heparins)
    appears to be safe for the baby. Enoxaparin is in the low molecular weight heparin family of medications. Enoxaparin was first made in 1981 and approved for...
    22 KB (1,681 words) - 16:41, 6 July 2024
  • The enzyme heparin-sulfate lyase (EC 4.2.2.8) catalyzes the chemical reaction Elimination of sulfate; appears to act on linkages between N-acetyl-D-lucosamine...
    1 KB (115 words) - 14:26, 26 August 2023
  • Thumbnail for Pleiotrophin
    known as heparin-binding brain mitogen (HBBM) or heparin-binding growth factor 8 (HBGF-8) or neurite growth-promoting factor 1 (NEGF1) or heparin affinity...
    14 KB (1,649 words) - 07:53, 21 December 2023
  • Thumbnail for Thrombus
    restore the level of clotting factors in the blood, as well as platelets and heparin to prevent further thrombi formation.[citation needed] A thrombus occurs...
    21 KB (2,276 words) - 05:36, 25 June 2024
  • Thumbnail for Argatroban
    Administration (FDA) for prophylaxis or treatment of thrombosis in people with heparin-induced thrombocytopenia (HIT). In 2002, it was approved for use during...
    7 KB (380 words) - 05:41, 13 July 2024
  • Thumbnail for Hematoma
    seepage and collection of blood may occur if heparin is given via an intramuscular route; to avoid this, heparin must be given intravenously or subcutaneously...
    6 KB (620 words) - 23:04, 4 June 2024
  • site due to their anticoagulant effect. This includes heparin and low molecular weight heparin products such as enoxaparin. There is some low certainty...
    22 KB (2,581 words) - 08:38, 3 December 2023
  • Thumbnail for Venous thrombosis
    low-molecular-weight heparin (LMWH) or unfractionated heparin, or increasingly with direct acting oral anticoagulants (DOAC). Those initially treated with heparins can...
    40 KB (4,613 words) - 02:51, 9 March 2024
  • Heparin mimicking polymers are synthetic compounds that possess similar characteristics to heparin, that is it can be used clinically as an anticoagulant...
    5 KB (724 words) - 04:29, 2 September 2020
  • Taurolidine/heparin, sold under the brand name Defencath, is a fixed-dose combination catheter lock solution used for central venous catheter instillation...
    7 KB (389 words) - 03:36, 10 January 2024
  • identified oversulfated chondroitin sulfate as a contaminant in the US heparin supply in 2007 and 2008, he had developed antibodies for dengue, yellow...
    40 KB (3,965 words) - 14:35, 7 July 2024
  • Heparin necrosis is a cutaneous condition and usually occurs between days 5 and 10 of heparin therapy. Warfarin necrosis List of cutaneous conditions...
    1 KB (49 words) - 11:09, 4 June 2024
  • Thumbnail for Heparin cofactor II
    Heparin cofactor II (HCII), a protein encoded by the SERPIND1 gene, is a coagulation factor that inhibits IIa, and is a cofactor for heparin and dermatan...
    12 KB (1,455 words) - 17:08, 23 April 2024
  • like heparin, act by interacting with heparin binding proteins, generally through ionic interactions or hydrogen bonding. Some examples of heparin binding...
    7 KB (884 words) - 16:14, 24 October 2023
  • Thumbnail for Cardiopulmonary bypass
    Because heparin is typically used in CPB, patients who are known to have the antibodies responsible for heparin-induced thrombocytopenia and heparin-induced...
    34 KB (3,950 words) - 00:29, 8 July 2024
  • Thumbnail for Fondaparinux
    Fondaparinux (category Heparins)
    an anticoagulant medication chemically related to low molecular weight heparins. It is marketed by Viatris. A generic version developed by Alchemia is...
    9 KB (711 words) - 10:19, 16 August 2023
  • Thumbnail for Thrombocytopenia
    who relapsed following splenectomy. Discontinuation of heparin is critical in a case of heparin-induced thrombocytopenia (HIT). Beyond that, however, clinicians...
    28 KB (2,658 words) - 15:10, 6 January 2024
  • suspended the manufacture of heparin, and launched an investigation. The investigation into the contamination has focused on raw heparin produced by one of Baxter's...
    40 KB (3,743 words) - 16:27, 3 June 2024