A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 80% of the liver's mass. These cells are involved in: Protein...
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Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells...
23 KB (2,635 words) - 06:03, 24 August 2024
Ballooning degeneration (redirect from Ballooning degeneration of hepatocytes)
degeneration, formally ballooning degeneration of hepatocytes, is a form of liver parenchymal cell (i.e. hepatocyte) death. The name is derived from the fact...
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Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity...
59 KB (6,727 words) - 06:01, 27 October 2024
In liver pathology, a ground glass hepatocyte, abbreviated GGH, is a liver parenchymal cell with a flat hazy and uniformly dull appearing cytoplasm on...
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Hepatocyte nuclear factors (HNFs) are a group of phylogenetically unrelated transcription factors that regulate the transcription of a diverse group of...
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Hepatocyte nuclear factor 4 alpha (HNF4A) also known as NR2A1 (nuclear receptor subfamily 2, group A, member 1) is a nuclear receptor that in humans is...
18 KB (2,230 words) - 15:35, 22 August 2024
hepatitis also leads to impaired hepatocyte differentiation, impairments in hepatocyte regeneration and hepatocyte de-differentiation into cholangiocyte...
21 KB (2,285 words) - 17:37, 21 October 2024
oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met...
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Disse) is a space between a hepatocyte, and a sinusoid in the liver. It contains the blood plasma. Microvilli of hepatocytes extend into this space, allowing...
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Feathery degeneration (redirect from Feathery degeneration of hepatocytes)
degeneration, formally feathery degeneration of hepatocytes, is a form of liver parenchymal cell (i.e. hepatocyte) death associated with cholestasis. Cells...
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When hepatocytes cannot proliferate, biliary epithelial cells are capable of turning into hepatocytes. The reverse can also occur, with hepatocytes turning...
22 KB (2,475 words) - 05:46, 24 September 2024
Hepatocyte nuclear factor 4 gamma (HNF4G) also known as NR2A2 (nuclear receptor subfamily 2, group A, member 2) is a nuclear receptor that in humans is...
4 KB (417 words) - 13:51, 10 July 2024
HNF4 (Hepatocyte Nuclear Factor 4) is a nuclear receptor protein mostly expressed in the liver, gut, kidney, and pancreatic beta cells that is critical...
5 KB (533 words) - 12:18, 21 October 2024
MST1 (redirect from Hepatocyte growth factor-like protein)
Macrophage-stimulating protein (MSP), also known as hepatocyte growth factor-like protein (HLP, HGFL, or HGFLP), is a protein that in humans is encoded...
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hepatocytes. Bile infarcts are marked by a large amount of pigmented tissue surrounded by a ring of necrotic hepatocytes. In some cases, hepatocyte degeneration...
112 KB (12,705 words) - 05:14, 2 November 2024
levels in pyrazole hepatocytes[clarification needed] had shown an increased amount of cell apoptosis when compared to control hepatocytes. In a 2015 study...
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homeobox B (hepatocyte nuclear factor 1 homeobox B), also known as HNF1B or transcription factor 2 (TCF2), is a human gene. HNF1B encodes hepatocyte nuclear...
9 KB (1,254 words) - 20:30, 30 May 2024
model system for the study of polarized human hepatocytes. Another well-characterized polarized hepatocyte cell line is the rat hepatoma-derived hybrid...
5 KB (577 words) - 05:27, 3 January 2023
cross-links, and single-strand breaks and alkali-labile sites in human hepatocyte L02 cells". Mutation Research/Fundamental and Molecular Mechanisms of...
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hyaline body or apoptotic body, is an eosinophilic globule of apoptotic hepatocyte cell fragments. Ultimately, the fragments are taken up by macrophages...
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digestion. The liver's highly specialized tissue, consisting mostly of hepatocytes, regulates a wide variety of high-volume biochemical reactions, including...
87 KB (10,329 words) - 05:37, 5 November 2024
injury. The HepaRG model is considered a surrogate for Primary Human Hepatocytes, which are the most pertinent model to reproduce the human liver functioning...
25 KB (2,666 words) - 15:23, 29 June 2024
mellitus. Oxytocin (OXT) Omentin Endothelin-1 Nesfatin-1 Irisin Betatrophin Hepatocyte growth factor (HGF) Fibroblast growth factor -Biomarkers with insulin-sensitizing...
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Mice hepatocytes produce 4-bromo-2,5-dimethoxy-phenol (BDMP), a previously unknown metabolite. Meanwhile, human, monkey and rabbit hepatocytes produce...
38 KB (4,198 words) - 06:35, 6 October 2024
(February 1985). "Ultraviolet light-induced DNA repair synthesis in hepatocytes from species of differing longevities". Mechanisms of Ageing and Development...
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cytoskeleton organization KRT18 extrinsic apoptotic signaling pathway KRT18 hepatocyte apoptotic process KRT18 cell-cell adhesion KRT19 Notch signaling pathway...
39 KB (3,017 words) - 13:44, 1 September 2024
models (e.g. DTI), and drug screening assays, such as stem cell-derived hepatocyte-like cells, that are capable of detecting toxicity early in the drug development...
39 KB (4,074 words) - 14:03, 4 October 2024
induction of apoptosis in human hepatoma cells (HCC-1.2) and primary rat hepatocyte cultures". BMC Pharmacology. 7 (Supplement 2): A65. doi:10.1186/1471-2210-7-S2-A65...
39 KB (3,617 words) - 15:10, 12 October 2024
Liver cytology (section Hepatocytes)
in charge of almost all the body’s metabolism. Main liver cells are hepatocytes, Kupffer cells, and hepatic stellate cells; each one with a specific...
9 KB (1,239 words) - 16:34, 15 August 2024