• Immunosenescence is the gradual deterioration of the immune system, brought on by natural age advancement. A 2020 review concluded that the adaptive immune...
    31 KB (3,559 words) - 04:47, 3 January 2025
  • self-proteins Allergy, immune response to harmless non-self proteins Histamine Immunosenescence, age-associated immune deficiency Steroids, commonly administered drugs...
    23 KB (2,168 words) - 06:54, 10 June 2024
  • allergy, immunology, inflammatory responses, mesenchymal stem cells and immunosenescence, and focusing on food allergy, immune complex diseases, immunoglobulin...
    27 KB (2,959 words) - 04:11, 5 November 2024
  • CD4+/CD8+ ratio is associated with ageing, and is an indicator of immunosenescence. Compared to CD4+ T-cells, CD8+ T-cells show a greater increase in...
    11 KB (1,159 words) - 05:00, 2 November 2024
  • systemic inflammation based on these cytokines (iAge) correlates with immunosenescence and predicts risk for cardiovascular disease, frailty syndrome, and...
    13 KB (1,458 words) - 05:15, 14 December 2024
  • of the immune system is also associated with immunosenescence, which arises due to aging. Immunosenescence is manifested by a decrease in reactivity to...
    21 KB (2,440 words) - 15:06, 23 May 2024
  • Thumbnail for Inflammaging
    to fight off pathogens, declines with age. Chronic inflammation and immunosenescence, which both increase with advanced chronological age, renders the elderly...
    26 KB (3,020 words) - 17:03, 14 May 2024
  • Thumbnail for Cancer
    Some of the association between aging and cancer is attributed to immunosenescence, errors accumulated in DNA over a lifetime and age-related changes...
    184 KB (20,031 words) - 07:25, 30 December 2024
  • S2CID 4887497. Rao, Sudha; Tu, Wenjuan (2016). "Mechanisms Underlying T Cell Immunosenescence: Aging and Cytomegalovirus Infection". Frontiers in Microbiology. 7:...
    5 KB (642 words) - 21:07, 11 April 2022
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    also linked to age-associated T cell dysfunction, contributing to immunosenescence. In persons infected with CMV about 10% of memory T cells are CMV-specific...
    58 KB (6,371 words) - 11:09, 24 November 2024
  • Thumbnail for Inflammation
    S2CID 18727504. Deeks SG (1 January 2011). "HIV infection, inflammation, immunosenescence, and aging". Annual Review of Medicine. 62: 141–55. doi:10...
    96 KB (9,751 words) - 20:07, 29 December 2024
  • proportional to thymus size). Though thymic involution has been linked to immunosenescence, it is not induced by senescence as the organ starts involuting from...
    19 KB (2,206 words) - 05:35, 27 December 2024
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    less of a response than those who are younger, a pattern known as Immunosenescence. Adjuvants commonly are used to boost immune response, particularly...
    139 KB (14,439 words) - 10:45, 30 December 2024
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    immune responses beginning to decline at around 50 years of age due to immunosenescence. In developed countries, obesity, alcoholism, and drug use are common...
    118 KB (13,487 words) - 01:29, 28 November 2024
  • ISBN 9780199997923 – via Google Books (preview). Pawelec, Graham (2008). Immunosenescence. Medical Intelligence Unit. New York: Springer. p. 110. ISBN 9780387768427...
    23 KB (2,050 words) - 09:16, 19 October 2024
  • Thumbnail for Old age
    stamina. Atherosclerosis can constrict blood flow. Immune-function loss (immunosenescence). Lungs may expand less efficiently, providing less oxygen. Mobility...
    109 KB (12,213 words) - 22:35, 2 January 2025
  • Thumbnail for T cell
    Chimeric antigen receptor T cell Gut-specific homing Immunoblast Immunosenescence Parafollicular cell also called C cell "5. Hematopoietic Stem Cells"...
    71 KB (9,061 words) - 03:46, 29 November 2024
  • Thumbnail for Everolimus
    response to the influenza vaccine in the elderly, possible by reversing immunosenescence. Everolimus treatment of mice results in reduced metabolic side effects...
    27 KB (2,534 words) - 20:49, 4 October 2024
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    on barn swallows and female collared flycatchers. Because of this immunosenescence (a decrease in immune function with age), older females infected with...
    73 KB (9,181 words) - 23:09, 25 November 2024
  • Thumbnail for Plasmablastic lymphoma
    The development of this variant appears due, at least in part, to immunosenescence, i.e. the immunodeficiency occurring in old age. Plasmablastic lymphoma...
    25 KB (3,060 words) - 21:02, 23 January 2024
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    et al. (June 2000). "Inflamm-aging. An evolutionary perspective on immunosenescence". Annals of the New York Academy of Sciences. 908 (1): 244–254. Bibcode:2000NYASA...
    35 KB (3,949 words) - 11:35, 2 January 2025
  • damaging it. The PAHs found in coal tar and air pollution induce immunosenescence and cytotoxicity in epidermal cells. It's possible that the skin can...
    36 KB (3,474 words) - 17:40, 3 January 2025
  • Biogerontology DNA repair § Senescence and apoptosis Geroprotector Hsp90 Immunosenescence Invariant NKT (iNKT) cells Klotho (biology) § Effects on aging Life...
    26 KB (2,027 words) - 18:28, 24 December 2024
  • Thumbnail for Aging-associated diseases
    Some of the association between aging and cancer is attributed to immunosenescence, errors accumulated in DNA over a lifetime and age-related changes...
    25 KB (2,580 words) - 15:00, 18 December 2024
  • Thumbnail for Hyperbaric medicine
    Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells : a prospective trial. Aging (Albany NY). PMID 33206062...
    92 KB (10,316 words) - 15:51, 28 December 2024
  • Thumbnail for Cellular senescence
    and promote killing similar to NK cells. Aging of the immune system (immunosenescence) results in a diminished capacity of the immune system to remove senescent...
    60 KB (6,714 words) - 05:35, 17 December 2024
  • Thumbnail for Oxford–AstraZeneca COVID-19 vaccine
    significantly reduced in those aged 90 year of age or older, attributable to immunosenescence. A vaccine is generally considered effective if the estimate is ≥50%...
    214 KB (17,080 words) - 15:51, 27 September 2024
  • Thumbnail for Follicular B helper T cells
    gradual diminishing of the body's immune system. This phenomenon called immunosenescence is largely due to a decline of T cell function, including the capacity...
    16 KB (1,936 words) - 01:42, 16 December 2023
  • inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging". Nature Aging. 1 (7): 598–615. doi:10...
    58 KB (7,163 words) - 21:11, 28 November 2024
  • Thumbnail for B3GAT1
    circulating CD8+ T cells is associated with other markers of immune ageing (immunosenescence) and may be associated with increased cancer risk in renal transplant...
    12 KB (1,391 words) - 18:35, 2 October 2024