Integrin beta-8 is a protein that in humans is encoded by the ITGB8 gene. This gene is a member of the integrin beta chain family and encodes a single-pass...
7 KB (825 words) - 23:51, 3 March 2023
Integrin beta-1 (ITGB1), also known as CD29, is a cell surface receptor that in humans is encoded by the ITGB1 gene. This integrin associates with integrin...
22 KB (2,600 words) - 22:18, 2 April 2024
In molecular biology, CD18 (Integrin beta chain-2) is an integrin beta chain protein that is encoded by the ITGB2 gene in humans. Upon binding with one...
11 KB (1,299 words) - 10:15, 11 December 2023
Integrin beta-7 is an integrin protein that in humans is encoded by the ITGB7 gene. It can pair with ITGA4 (CD49d) to form the heterodimeric integrin...
11 KB (1,414 words) - 06:32, 25 December 2023
Integrin beta-3 (β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene. CD61 is a cluster of differentiation found on thrombocytes. The...
9 KB (1,050 words) - 17:56, 13 January 2024
Integrin beta-5 is a protein that in humans is encoded by the ITGB5 gene. Integrin, beta 5 has been shown to interact with PTK2, Annexin A5 and PAK4. ITGB5...
10 KB (1,273 words) - 04:11, 25 December 2023
Integrins are transmembrane receptors that help cell-cell and cell-extracellular matrix (ECM) adhesion. Upon ligand binding, integrins activate signal...
36 KB (3,929 words) - 14:48, 30 May 2024
Integrin beta-6 is a protein that in humans is encoded by the ITGB6 gene. It is the β6 subunit of the integrin αvβ6. Integrins are αβ heterodimeric glycoproteins...
35 KB (4,041 words) - 17:11, 23 December 2023
Integrin, beta 4 (ITGB4) also known as CD104 (Cluster of Differentiation 104), is a human gene. Integrins are heterodimers composed of alpha and beta...
12 KB (1,489 words) - 22:47, 18 October 2022
protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain...
8 KB (992 words) - 05:25, 1 January 2024
Integrin alpha M (ITGAM) is one protein subunit that forms heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1)...
15 KB (1,716 words) - 17:02, 7 November 2023
αVβ3 is a type of integrin that is a receptor for vitronectin. It consists of two components, integrin alpha V and integrin beta 3 (CD61), and is expressed...
4 KB (475 words) - 00:04, 28 November 2023
et al. (May 1996). "Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and...
70 KB (8,485 words) - 08:12, 19 May 2024
VLA-4 (redirect from Integrin alpha4beta1)
Integrin α4β1 (very late antigen-4) is an integrin dimer. It is composed of CD49d (alpha 4) and CD29 (beta 1). The alpha 4 subunit is 155 kDa, and the...
9 KB (1,032 words) - 14:42, 18 March 2024
chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain...
4 KB (444 words) - 18:22, 24 April 2024
Integrin subunit beta like 1 is a protein that in humans is encoded by the ITGBL1 gene. This gene encodes a beta integrin-related protein that is a member...
3 KB (481 words) - 15:38, 15 June 2023
Integrin alpha-3 is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit. Together with beta-1 subunit, it makes...
5 KB (662 words) - 05:18, 30 January 2023
(2008). "Integrins and the activation of latent transforming growth factor [beta]1 - An intimate relationship". European Journal of Cell Biology. 87 (8–9):...
20 KB (2,419 words) - 09:58, 28 June 2024
Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene. ITGA2B, also known as CD41, encodes integrin alpha chain 2b. Integrins are...
6 KB (722 words) - 12:09, 22 December 2023
soluble integrin-alkaline phosphatase chimera to characterize integrin alpha 8 beta 1 receptor interactions with tenascin: murine alpha 8 beta 1 binds...
5 KB (625 words) - 03:01, 4 January 2024
integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; ITGB1, ITGB3, ITGB5, ITGB6, and ITGB8)...
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beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1...
10 KB (1,239 words) - 08:31, 10 June 2024
common beta chain. They are found on a wide variety of cell types including T cells (the NKT cells), NK cells, fibroblasts and platelets. Integrins are involved...
6 KB (686 words) - 09:04, 10 June 2024
alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha...
10 KB (1,210 words) - 20:44, 2 June 2024
Cell adhesion molecule (section Integrins)
transcription. Integrins are heterodimeric, as they consist of an alpha and beta subunit. There are currently 18 alpha subunits and 8 beta subunits, which...
16 KB (1,905 words) - 07:17, 26 April 2024
encoded by the ITGAE gene. CD103 binds integrin beta 7 (β7– ITGB7) to form the complete heterodimeric integrin molecule αEβ7, which has no distinct name...
12 KB (1,539 words) - 06:44, 10 June 2024
to integrin α4β7 (LPAM-1, lymphocyte Peyer's patch adhesion molecule 1, a dimer of Integrin alpha-4 and Integrin beta-7), blocking the α4β7 integrin results...
26 KB (2,381 words) - 11:54, 7 July 2024
ADAM2 (redirect from Beta fertilin)
JM (October 1999). "Role of the integrin-associated protein CD9 in binding between sperm ADAM 2 and the egg integrin alpha6beta1: implications for murine...
6 KB (685 words) - 02:54, 28 November 2023
encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell...
7 KB (934 words) - 22:12, 3 March 2023
join with beta 1 to form an integrin that binds to the extracellular matrix protein laminin-1. The primary binding partners of alpha-7 integrin are laminin-1...
26 KB (3,169 words) - 03:34, 10 March 2024