Invadopodia are actin-rich protrusions of the plasma membrane that are associated with degradation of the extracellular matrix in cancer invasiveness...
13 KB (1,535 words) - 03:47, 12 June 2024
different specialized cells exhibit these dynamic structures such as invadopodia, (invasive cancer cells), osteoclasts, vascular smooth muscle cells,...
18 KB (2,213 words) - 02:31, 23 October 2024
are highly linked with the presence of invadopodia, protrusive and adhesive structures on cancer cells. Invadopodia have been shown to concentrate MMPs (including...
24 KB (2,812 words) - 07:02, 8 October 2024
behavior of whole cells, for the study of cellular protrusions called invadopodia and podosomes, which are protrusive structures in cancer cells and play...
35 KB (4,045 words) - 17:17, 18 October 2024
"supramembrane" structures such as caveolae, postsynaptic density, podosomes, invadopodia, focal adhesion, and different types of cell junctions. These structures...
59 KB (6,906 words) - 20:31, 27 October 2024
begins the process of metastasis. The cell develops structures called invadopodia, which are highly concentrated in several proteases and have a highly...
42 KB (5,270 words) - 21:20, 8 October 2024
been used to identify the molecular composition of breast cancer cell invadopodia, which are important for metastasis. Biotin-based proximity labeling...
18 KB (2,018 words) - 01:47, 11 April 2024
their initial impetus. These entities may take the form of pseudopodia, invadopodia, or non-apoptotic membrane blebs. The unfavorable kinetics of actin oligomer...
7 KB (843 words) - 08:35, 18 June 2024
cytoskeleton, namely the formation of podosome rosettes, otherwise known as invadopodia. SU6656 was initially published as a Src family kinase inhibitor with...
3 KB (277 words) - 13:19, 13 April 2022
potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells". Cancer Research. 54 (21): 5702–10...
17 KB (2,086 words) - 09:37, 10 March 2024
microspikes, pseudopods, thin filopodia, thick filopodia, gliopodia, myopodia, invadopodia, podosomes, telopodes, tunneling nanotubes and dendrites. Filopodia are...
20 KB (2,042 words) - 07:13, 2 November 2024
branching. Cortactin is important in promoting lamellipodia formation, invadopodia formation, cell migration, and endocytosis. In humans, cortactin is encoded...
21 KB (2,576 words) - 11:30, 27 March 2024
formation of invadopodia, actin-based protrusiona that are hotspots for secretion of matrix-degrading proteinases. In 2013, she found that invadopodia and exosomes...
7 KB (707 words) - 04:39, 28 April 2024
believed to play a key role in the cancer cell invasiveness by controlling invadopodia, and thus mediating efficient ECM degradation. GRCh38: Ensembl release...
13 KB (1,692 words) - 05:37, 29 August 2024
This protein is known to be involved in the regulation of developing invadopodias, which are structures typical of malignant tumor cells and responsible...
46 KB (6,026 words) - 16:01, 26 September 2024
surface called filopodia. Recent study shows that fascin also localizes to invadopodia, membrane protrusions formed at the adherent cell surface that facilitate...
14 KB (1,556 words) - 02:07, 30 March 2024
cancer cell invasion by regulating cofilin subcellular localization in invadopodia. Elevated O-GlcNAc has been associated with diabetes. Pancreatic β cells...
108 KB (12,376 words) - 16:09, 30 March 2024
"c-Src differentially regulates the functions of microtentacles and invadopodia". Oncogene. 29 (48): 6402–8. doi:10.1038/onc.2010.360. PMC 4073667. PMID 20956943...
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protein Interbilayer forces in membrane fusion Intracellular membranes Invadopodia Inward-rectifier potassium ion channel Ion channel Ionotropic effect...
15 KB (1,545 words) - 18:32, 17 August 2024
ISBN 978-0-12-432565-4. Chan KT, Cortesio CL, Huttenlocher A (2009). "FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer...
41 KB (4,724 words) - 09:43, 11 December 2023
ESCRT machinery Establishing polarity Exploring the nucleus Imaging Invadopodia and podosomes Mechanotransduction Microtubule dynamics Mitochondria Stem...
15 KB (1,603 words) - 16:10, 26 March 2024
some physiological processes involved in metastasis, like angiogenesis, invadopodia, extravasation, and chromosomal instability. Twist also protects cancer...
20 KB (2,365 words) - 15:48, 21 December 2023
Jønson L, et al. (2006). "RNA-binding IMPs promote cell adhesion and invadopodia formation". EMBO J. 25 (7): 1456–68. doi:10.1038/sj.emboj.7601039. PMC 1440323...
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adaptor proteins are associated with actin-regulating protein WIP in invadopodia". Cellular Signalling. 27 (7): 1499–508. doi:10.1016/j.cellsig.2015.03...
14 KB (1,716 words) - 22:07, 21 May 2024
Chellini L, Sestito R, Zancla A, et al. (March 2021). "Endothelin-1 drives invadopodia and interaction with mesothelial cells through ILK". Cell Reports. 34...
12 KB (1,412 words) - 20:44, 24 November 2023
Vikesaa, J., et al. 2006. RNA-binding IMPs promote cell adhesion and invadopodia formation. EMBO 25: 1456-1468. Goodison, S., et al. 1999. CD44 Cell adhesion...
5 KB (713 words) - 01:16, 19 July 2024
the excess centrosomes of cancer cells, Myo10 is a key component of invadopodia, filopodia-related protrusions that cancer cells use to invade their...
38 KB (4,417 words) - 11:00, 11 April 2024
that it reduces Rho-GTPases and it prevents melanoma cells from forming invadopodia, breaking down the extracellular matrix, and growing as tumors. It does...
11 KB (1,388 words) - 14:59, 24 December 2023
Buccione R (February 2009). "Faciogenital dysplasia protein Fgd1 regulates invadopodia biogenesis and extracellular matrix degradation and is up-regulated in...
13 KB (1,607 words) - 23:01, 27 July 2024