• Thumbnail for Invadopodia
    Invadopodia are actin-rich protrusions of the plasma membrane that are associated with degradation of the extracellular matrix in cancer invasiveness...
    13 KB (1,535 words) - 03:47, 12 June 2024
  • Thumbnail for Podosome
    different specialized cells exhibit these dynamic structures such as invadopodia, (invasive cancer cells), osteoclasts, vascular smooth muscle cells,...
    18 KB (2,213 words) - 02:31, 23 October 2024
  • Thumbnail for MMP2
    are highly linked with the presence of invadopodia, protrusive and adhesive structures on cancer cells. Invadopodia have been shown to concentrate MMPs (including...
    24 KB (2,812 words) - 07:02, 8 October 2024
  • Thumbnail for Gelatin
    behavior of whole cells, for the study of cellular protrusions called invadopodia and podosomes, which are protrusive structures in cancer cells and play...
    35 KB (4,045 words) - 17:17, 18 October 2024
  • Thumbnail for Cell membrane
    "supramembrane" structures such as caveolae, postsynaptic density, podosomes, invadopodia, focal adhesion, and different types of cell junctions. These structures...
    59 KB (6,906 words) - 20:31, 27 October 2024
  • Thumbnail for Metastatic breast cancer
    begins the process of metastasis. The cell develops structures called invadopodia, which are highly concentrated in several proteases and have a highly...
    42 KB (5,270 words) - 21:20, 8 October 2024
  • Thumbnail for Proximity labeling
    been used to identify the molecular composition of breast cancer cell invadopodia, which are important for metastasis. Biotin-based proximity labeling...
    18 KB (2,018 words) - 01:47, 11 April 2024
  • their initial impetus. These entities may take the form of pseudopodia, invadopodia, or non-apoptotic membrane blebs. The unfavorable kinetics of actin oligomer...
    7 KB (843 words) - 08:35, 18 June 2024
  • Thumbnail for SU6656
    cytoskeleton, namely the formation of podosome rosettes, otherwise known as invadopodia. SU6656 was initially published as a Src family kinase inhibitor with...
    3 KB (277 words) - 13:19, 13 April 2022
  • Thumbnail for Fibroblast activation protein, alpha
    potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells". Cancer Research. 54 (21): 5702–10...
    17 KB (2,086 words) - 09:37, 10 March 2024
  • Thumbnail for Filopodia
    microspikes, pseudopods, thin filopodia, thick filopodia, gliopodia, myopodia, invadopodia, podosomes, telopodes, tunneling nanotubes and dendrites. Filopodia are...
    20 KB (2,042 words) - 07:13, 2 November 2024
  • Thumbnail for Cortactin
    branching. Cortactin is important in promoting lamellipodia formation, invadopodia formation, cell migration, and endocytosis. In humans, cortactin is encoded...
    21 KB (2,576 words) - 11:30, 27 March 2024
  • formation of invadopodia, actin-based protrusiona that are hotspots for secretion of matrix-degrading proteinases. In 2013, she found that invadopodia and exosomes...
    7 KB (707 words) - 04:39, 28 April 2024
  • Thumbnail for PDPN
    believed to play a key role in the cancer cell invasiveness by controlling invadopodia, and thus mediating efficient ECM degradation. GRCh38: Ensembl release...
    13 KB (1,692 words) - 05:37, 29 August 2024
  • Thumbnail for Invasion (cancer)
    This protein is known to be involved in the regulation of developing invadopodias, which are structures typical of malignant tumor cells and responsible...
    46 KB (6,026 words) - 16:01, 26 September 2024
  • Thumbnail for Fascin
    surface called filopodia. Recent study shows that fascin also localizes to invadopodia, membrane protrusions formed at the adherent cell surface that facilitate...
    14 KB (1,556 words) - 02:07, 30 March 2024
  • Thumbnail for O-GlcNAc
    cancer cell invasion by regulating cofilin subcellular localization in invadopodia. Elevated O-GlcNAc has been associated with diabetes. Pancreatic β cells...
    108 KB (12,376 words) - 16:09, 30 March 2024
  • "c-Src differentially regulates the functions of microtentacles and invadopodia". Oncogene. 29 (48): 6402–8. doi:10.1038/onc.2010.360. PMC 4073667. PMID 20956943...
    5 KB (457 words) - 15:58, 28 September 2024
  • protein Interbilayer forces in membrane fusion Intracellular membranes Invadopodia Inward-rectifier potassium ion channel Ion channel Ionotropic effect...
    15 KB (1,545 words) - 18:32, 17 August 2024
  • Thumbnail for PTK2
    ISBN 978-0-12-432565-4. Chan KT, Cortesio CL, Huttenlocher A (2009). "FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer...
    41 KB (4,724 words) - 09:43, 11 December 2023
  • ESCRT machinery Establishing polarity Exploring the nucleus Imaging Invadopodia and podosomes Mechanotransduction Microtubule dynamics Mitochondria Stem...
    15 KB (1,603 words) - 16:10, 26 March 2024
  • Thumbnail for Twist-related protein 1
    some physiological processes involved in metastasis, like angiogenesis, invadopodia, extravasation, and chromosomal instability. Twist also protects cancer...
    20 KB (2,365 words) - 15:48, 21 December 2023
  • Thumbnail for IGF2BP3
    Jønson L, et al. (2006). "RNA-binding IMPs promote cell adhesion and invadopodia formation". EMBO J. 25 (7): 1456–68. doi:10.1038/sj.emboj.7601039. PMC 1440323...
    7 KB (905 words) - 17:01, 27 December 2023
  • Thumbnail for WIPF1
    adaptor proteins are associated with actin-regulating protein WIP in invadopodia". Cellular Signalling. 27 (7): 1499–508. doi:10.1016/j.cellsig.2015.03...
    14 KB (1,716 words) - 22:07, 21 May 2024
  • Thumbnail for RAC3
    Chellini L, Sestito R, Zancla A, et al. (March 2021). "Endothelin-1 drives invadopodia and interaction with mesothelial cells through ILK". Cell Reports. 34...
    12 KB (1,412 words) - 20:44, 24 November 2023
  • Vikesaa, J., et al. 2006. RNA-binding IMPs promote cell adhesion and invadopodia formation. EMBO 25: 1456-1468. Goodison, S., et al. 1999. CD44 Cell adhesion...
    5 KB (713 words) - 01:16, 19 July 2024
  • Thumbnail for MYO10
    the excess centrosomes of cancer cells, Myo10 is a key component of invadopodia, filopodia-related protrusions that cancer cells use to invade their...
    38 KB (4,417 words) - 11:00, 11 April 2024
  • Thumbnail for GMP reductase
    that it reduces Rho-GTPases and it prevents melanoma cells from forming invadopodia, breaking down the extracellular matrix, and growing as tumors. It does...
    11 KB (1,388 words) - 14:59, 24 December 2023
  • Thumbnail for FGD1
    Buccione R (February 2009). "Faciogenital dysplasia protein Fgd1 regulates invadopodia biogenesis and extracellular matrix degradation and is up-regulated in...
    13 KB (1,607 words) - 23:01, 27 July 2024