• Thumbnail for Ivacaftor
    lumacaftor/ivacaftor, tezacaftor/ivacaftor, and elexacaftor/tezacaftor/ivacaftor which are used to treat people with cystic fibrosis. Ivacaftor was developed...
    34 KB (3,157 words) - 19:11, 14 June 2024
  • Elexacaftor/tezacaftor/ivacaftor, sold under the brand names Trikafta and Kaftrio, is a fixed-dose combination medication used to treat cystic fibrosis...
    38 KB (3,107 words) - 08:02, 24 June 2024
  • Thumbnail for Lumacaftor/ivacaftor
    Lumacaftor/ivacaftor, sold under the brand name Orkambi among others, is a combination of lumacaftor and ivacaftor used to treat people with cystic fibrosis...
    15 KB (1,370 words) - 07:39, 4 July 2024
  • Thumbnail for Vertex Pharmaceuticals
    Reimbursement of ORKAMBI® (lumacaftor/ivacaftor) and SYMKEVI® (tezacaftor/ivacaftor) in Combination With KALYDECO® (ivacaftor)". www.businesswire.com. 21 October...
    37 KB (3,628 words) - 05:20, 13 September 2024
  • Thumbnail for Tezacaftor
    with ivacaftor under the brand name Symdeko. It was approved by the U.S. FDA in 2018. The combination of elexacaftor, tezacaftor, and ivacaftor is being...
    11 KB (724 words) - 19:14, 30 November 2023
  • Thumbnail for Elexacaftor
    available in a single pill with ivacaftor and tezacaftor; the fixed-dose combination, elexacaftor/tezacaftor/ivacaftor (brand name Trikafta), is used to...
    7 KB (286 words) - 14:34, 17 May 2024
  • cell surface. It is available in a single pill with ivacaftor; the combination, lumacaftor/ivacaftor (brand name Orkambi), is used to treat people with...
    4 KB (171 words) - 13:20, 28 March 2024
  • Thumbnail for Cystic fibrosis
    cystic fibrosis. Ivacaftor is a medication taken by mouth for the treatment of CF due to a number of specific mutations responsive to ivacaftor-induced CFTR...
    161 KB (18,074 words) - 10:17, 8 September 2024
  • R07AX01 Nitric oxide R07AX02 Ivacaftor R07AX30 Ivacaftor and lumacaftor R07AX31 Ivacaftor and tezacaftor R07AX32 Ivacaftor, tezacaftor and elexacaftor...
    1,000 bytes (237 words) - 06:04, 4 January 2021
  • Thumbnail for Barbiturate
    Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
    44 KB (4,698 words) - 17:17, 5 June 2024
  • Thumbnail for Cocaine
    Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
    177 KB (18,939 words) - 20:08, 9 September 2024
  • Thumbnail for Ketamine
    Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
    117 KB (11,360 words) - 18:24, 12 September 2024
  • Thumbnail for Alcohol (drug)
    Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
    236 KB (24,287 words) - 10:59, 10 September 2024
  • Thumbnail for Gabapentin
    Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
    91 KB (8,927 words) - 17:50, 11 September 2024
  • Thumbnail for Lorazepam
    Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
    82 KB (8,613 words) - 08:18, 9 September 2024
  • Thumbnail for Amitriptyline
    Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
    92 KB (8,671 words) - 18:15, 17 August 2024
  • Thumbnail for Buprenorphine
    Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
    82 KB (7,486 words) - 02:58, 12 September 2024
  • Thumbnail for Icenticaftor
    (COPD) and cystic fibrosis. The drug is being developed by Novartis. Like ivacaftor (which is marketed as Kalydeco), icenticaftor functions by acting as a...
    6 KB (241 words) - 16:38, 7 June 2024
  • Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
    29 KB (3,270 words) - 15:49, 13 July 2024
  • Thumbnail for Domperidone
    Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
    63 KB (5,650 words) - 05:22, 28 August 2024
  • Thumbnail for Cystic fibrosis transmembrane conductance regulator
    been a drug target in efforts to find treatments for related conditions. Ivacaftor (trade name Kalydeco, developed as VX-770) is a drug approved by the FDA...
    60 KB (6,439 words) - 10:20, 8 September 2024
  • Thumbnail for Primary ciliary dyskinesia
    PMID 19436518. Davis, Pamela B.; Yasothan, Uma; Kirkpatrick, Peter (2012-04-30). "Ivacaftor". Nature Reviews Drug Discovery. 11 (5): 349–350. doi:10.1038/nrd3723...
    42 KB (4,008 words) - 15:40, 4 January 2024
  • Thumbnail for Propranolol
    Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
    53 KB (4,803 words) - 18:16, 12 September 2024
  • Thumbnail for Pharmacology of ethanol
    Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
    96 KB (10,550 words) - 10:57, 20 July 2024
  • Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
    28 KB (2,361 words) - 05:21, 18 July 2024
  • Thumbnail for Benzocaine
    Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
    23 KB (2,045 words) - 20:50, 16 August 2024
  • Thumbnail for Cholesterol
    Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
    80 KB (8,653 words) - 20:33, 10 September 2024
  • but the arrangement with CFF continued and resulted in the discovery of ivacaftor in 2005 and the approval of that drug in 2012.[citation needed] Aurora...
    16 KB (1,650 words) - 03:02, 14 August 2024
  • Thumbnail for Lidocaine
    Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
    50 KB (4,562 words) - 15:59, 6 September 2024
  • Thumbnail for Pethidine
    Glibenclamide Lonidamine Piretanide Activators 1,7-Phenanthroline 1,10-Phenanthroline 4,7-Phenanthroline 7,8-Benzoquinoline Ivacaftor Phenanthridine...
    32 KB (3,136 words) - 10:53, 18 May 2024