potassium channel 4 (GIRK-4) is a protein that in humans is encoded by the KCNJ5 gene and is a type of G protein-gated ion channel. Potassium channels are...
10 KB (1,206 words) - 22:33, 16 July 2024
Familial hyperaldosteronism type III is caused by mutations in the KCNJ5 gene. The KCNJ5 gene provides instructions for making a protein that functions as...
6 KB (605 words) - 12:10, 25 July 2024
phenotype characteristics of type 13 long QT syndrome with mutation in KCNJ5 (Kir3.4-G387R)". Heart Rhythm. 10 (10): 1500–6. doi:10.1016/j.hrthm.2013...
64 KB (6,615 words) - 10:17, 11 August 2024
Mutations in a related gene encoding a similar potassium ion channel, KCNJ5, have been identified in some of those with type 2 Andersen–Tawil, but in...
23 KB (2,389 words) - 11:02, 11 August 2024
producing adenoma have somatic gain-of-function mutations in a single gene (KCNJ5). This gene is mutated in inherited cases of early onset primary aldosteronism...
30 KB (2,996 words) - 05:10, 25 July 2024
HGNC:6263 P63252 8010 KCNJ3 HGNC:6264 P48549 8011 KCNJ4 HGNC:6265 P48050 8012 KCNJ5 HGNC:6266 P48544 8013 KCNJ6 HGNC:6267 P48051 8014 KCNJ8 HGNC:6269 Q15842...
277 KB (17 words) - 18:41, 6 October 2024
regulation: recent milestones on the long and winding road from electrocortin to KCNJ5, GPER, and beyond". Hypertension. 63 (1): 19–21. doi:10.1161/HYPERTENSIONAHA...
84 KB (8,932 words) - 21:51, 31 August 2024
Mutations in this gene may increase the late sodium current INa. LQT13 600734 KCNJ5 Also known as GIRK4, encodes G protein-sensitive inwardly rectifying potassium...
28 KB (2,823 words) - 11:02, 11 August 2024
crucial role in aldosterone production. Somatic mutations in genes like KCNJ5 and CACNA1D can lead to an overexpression of CYP11B2 and increased production...
6 KB (565 words) - 13:51, 22 August 2024
potassium inwardly rectifying channel, subfamily J, member 5 Identifiers Symbol KCNJ5 Alt. symbols Kir3.4, CIR, KATP1, GIRK4 IUPHAR 437 NCBI gene 3762 HGNC 6266...
9 KB (804 words) - 23:15, 23 May 2023
heteromeric channel KCNJ9 Kir3.3 GIRK3 Kir3.1, Kir3.2 to form heteromeric channel KCNJ5 Kir3.4 GIRK4 Kir3.1, Kir3.2, Kir3.3 KCNJ10 Kir4.1 Kir1.2 Kir4.2, Kir5.1...
22 KB (2,007 words) - 01:49, 26 March 2024
found in the genes of K+ channels, including mutations in KCNE1-5, KCNH2, KCNJ5 or ABCC9 among others. Six variations in genes of Na+ channels that include...
164 KB (18,159 words) - 13:21, 13 September 2024
KCNH8 KCNIP1 KCNIP4 KCNJ10 KCNJ12 KCNJ13 KCNJ14 KCNJ15 KCNJ16 KCNJ3 KCNJ4 KCNJ5 KCNJ6 KCNJ8 KCNJ9 KCNK1 KCNK10 KCNK12 KCNK13 KCNK15 KCNK16 KCNK17 KCNK18...
15 KB (1,545 words) - 18:32, 17 August 2024
hetero-tetrameric pore-forming complex. KCNJ3 has been shown to interact with KCNJ5. G protein-coupled inwardly-rectifying potassium channel Inward-rectifier...
9 KB (1,129 words) - 23:38, 16 July 2024
610380; TGFBR2 Long QT syndrome 12; 612955; SNT1 Long QT syndrome 13; 613485; KCNJ5 Long QT syndrome-1; 192500; KCNQ1 Long QT syndrome-10; 611819; SCN4B Long...
234 KB (18,877 words) - 15:43, 9 May 2024