LM22A-4 is a synthetic, selective small-molecule partial agonist of TrkB (EC50 for TrkB activation = 200–500 pM; IC50 for inhibition of BDNF binding to...
5 KB (300 words) - 03:40, 3 December 2023
Testosterone (redirect from 4-testosterone)
in relation to the stages of development. The first period occurs between 4 and 6 weeks of the gestation. Examples include genital virilisation such as...
149 KB (15,717 words) - 06:34, 13 August 2024
the Treatment of Alzheimer's Disease". Journal of Alzheimer's Disease. 45 (4): 985–1000. doi:10.3233/JAD-142814. PMID 25649658. Siller R, Greenhough S...
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8,2'-THF 4'-DMA-7,8-DHF 7,3'-DHF 7,8-DHF 7,8,2'-THF 7,8,3'-THF Amitriptyline BDNF BNN-20 Deoxygedunin Deprenyl Diosmetin DMAQ-B1 HIOC LM22A-4 N-Acetylserotonin...
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Dexamethasone (redirect from Dexacen-4)
"Dexamethasone 4.0 mg/ml injection – Summary of Product Characteristics (SPC)". electronic Medicines Compendium. Merck Sharp & Dohme Limited. 4 December 2013...
68 KB (5,999 words) - 20:41, 31 August 2024
Neurotrophin (section Neurotrophin-4)
brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). The term neurotrophic factor generally refers to these four neurotrophins...
27 KB (3,071 words) - 04:54, 3 June 2024
an octanol-water partition coefficient (pH 7.4) of 3.0, while the log P of the free base was reported as 4.92. Solubility of the free base amitriptyline...
92 KB (8,671 words) - 18:15, 17 August 2024
8,2'-THF 4'-DMA-7,8-DHF 7,3'-DHF 7,8-DHF 7,8,2'-THF 7,8,3'-THF Amitriptyline BDNF BNN-20 Deoxygedunin Deprenyl Diosmetin DMAQ-B1 HIOC LM22A-4 N-Acetylserotonin...
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pharmacological stimuli". Journal of Applied Physiology. 41 (4): 523–7. doi:10.1152/jappl.1976.41.4.523. PMID 985395. Gunnell D, Miller LL, Rogers I, Holly...
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Vol. 53. pp. 289–98. doi:10.1007/978-3-7091-6467-9_25. ISBN 978-3-211-83114-4. PMID 9700665. Ziganshina LE, Abakumova T, Nurkhametova D, Ivanchenko K, et al...
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levels of ALTO-100 are reached within 4 to 5 days. The elimination half-life of ALTO-100 has ranged from 17.4 to 20.5 hours in a few different clinical...
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sugar chains of human erythropoietins". Glycobiology. 1 (4): 337–46. doi:10.1093/glycob/1.4.337. PMID 1820196. Semba RD, Juul SE (August 2002). "Erythropoietin...
31 KB (3,430 words) - 05:24, 28 August 2024
Nintedanib (category 4-Methylpiperazin-1-yl compounds)
results in an oral bioavailability of about 4.7% with a 100 mg tablet. The drug reaches peak plasma levels in 2 to 4 hours after oral intake in the form of...
34 KB (3,021 words) - 12:39, 5 August 2024
Diosmetin DMAQ-B1 Eutropoflavin (4'-DMA-7,8-DHF) HIOC LM22A-4 N-Acetylserotonin (NAS) Neurotrophin-3 (NT-3) Neurotrophin-4 (NT-4) Norwogonin (5,7,8-THF) R7...
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fifth FGFR protein, FGFR5, has also been identified. In contrast to FGFRs 1-4, it lacks a cytoplasmic tyrosine kinase domain, and one isoform, FGFR5γ, only...
28 KB (3,078 words) - 07:46, 3 June 2024
Members FGF11, FGF12, FGF13, and FGF14, also known as FGF homologous factors 1-4 (FHF1-FHF4), have been shown to have distinct functions compared to the FGFs...
25 KB (3,124 words) - 21:38, 18 August 2024
lymphangiogenesis promotes tumour metastasis". The EMBO Journal. 20 (4): 672–682. doi:10.1093/emboj/20.4.672. PMC 145430. PMID 11179212. Retrieved 3 February 2022...
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2 and 3, as well as fibroblast growth factor receptors (FGFR) 1, 2, 3 and 4, platelet-derived growth factor receptor (PDGFR) alpha, c-Kit, and the RET...
11 KB (934 words) - 23:22, 24 August 2024
Eutropoflavin (redirect from 4'-dimethylamino-7,8-dihydroxyflavone)
Eutropoflavin (4'-Dimethylamino-7,8-dihydroxyflavone) is a synthetic flavone and selective small-molecule agonist of TrkB, the main receptor of brain-derived...
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glucose and d acids". review. The Journal of Nutrition. 136 (4): 873–76. doi:10.1093/jn/136.4.873. PMC 1853259. PMID 16549443. Vaulont S, Vasseur-Cognet...
121 KB (13,799 words) - 18:32, 22 August 2024
g/mol. The chemical name is N-(2-{2-dimethylaminoethyl-methylamino}-4-methoxy-5-{[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide mesylate...
17 KB (1,489 words) - 05:47, 7 April 2024
Neuregulin 4 (NRG4) Neurotrophins Brain-derived neurotrophic factor (BDNF) Nerve growth factor (NGF) Neurotrophin-3 (NT-3) Neurotrophin-4 (NT-4) Placental...
10 KB (1,131 words) - 19:14, 31 March 2024
8,2'-THF 4'-DMA-7,8-DHF 7,3'-DHF 7,8-DHF 7,8,2'-THF 7,8,3'-THF Amitriptyline BDNF BNN-20 Deoxygedunin Deprenyl Diosmetin DMAQ-B1 HIOC LM22A-4 N-Acetylserotonin...
21 KB (1,649 words) - 23:02, 17 April 2024
8,2'-THF 4'-DMA-7,8-DHF 7,3'-DHF 7,8-DHF 7,8,2'-THF 7,8,3'-THF Amitriptyline BDNF BNN-20 Deoxygedunin Deprenyl Diosmetin DMAQ-B1 HIOC LM22A-4 N-Acetylserotonin...
3 KB (374 words) - 18:45, 17 July 2023
treatment of advanced colorectal cancer". The Oncologist. 12 (4): 443–50. doi:10.1634/theoncologist.12-4-443. PMID 17470687. Karpinska A, Magiera G, Kwapiszewska...
73 KB (6,440 words) - 02:59, 3 September 2024
Teprotumumab in a Patient With Thyroid Eye Disease". AACE Clinical Case Reports. 8 (4): 148–149. doi:10.1016/j.aace.2022.01.004. PMC 9363510. PMID 35959086. "FDA...
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"Serum FGF-21 levels in type 2 diabetic patients". Endocrine Research. 36 (4): 142–8. doi:10.3109/07435800.2011.558550. PMID 21973233. S2CID 24454698....
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patients treated with chemotherapy alone before and after liver resection, to 55.4 months for those that also received cetuximab. A multicenter, single arm,...
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mutations. Affected individuals classically present with short stature between −4 and −10 standard deviations below median height, obesity, craniofacial abnormalities...
35 KB (4,573 words) - 09:59, 28 August 2024
Imatinib (category 4-Methylpiperazin-1-yl compounds)
hyperpigmentation of the gingiva. The median onset of hair color change is 4 weeks after initiation of therapy (but may occur over a year after initiation)...
71 KB (6,702 words) - 05:32, 9 August 2024