Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. When LIF levels drop, the...
13 KB (1,583 words) - 04:50, 17 August 2024
Differentiation 118), is a subunit of a receptor for leukemia inhibitory factor. The leukemia inhibitory factor (LIF) is a polyfunctional cytokine that affects...
11 KB (1,325 words) - 16:37, 6 April 2024
motility factor Bone morphogenetic proteins (BMPs) Ciliary neurotrophic factor family Ciliary neurotrophic factor (CNTF) Leukemia inhibitory factor (LIF)...
10 KB (1,131 words) - 19:14, 31 March 2024
unknown. The CNTF family of neurotrophic factors includes ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), interleukin-6 (IL-6), prolactin...
16 KB (1,784 words) - 04:08, 6 January 2024
group of cytokines. Of these cytokines it most closely resembles leukemia inhibitory factor (LIF) in both structure and function. As yet poorly defined, it...
32 KB (4,332 words) - 11:35, 29 July 2024
Implantation (embryology) (section Other factors)
there is no evidence to support their involvement in hatching. Leukemia inhibitory factor (LIF) is a pro-inflammatory cytokine expressed in the endometrium...
51 KB (5,914 words) - 21:10, 16 August 2024
with gp130, such as cardiotrophin 1 (CT-1), leukemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), oncostatin M (OSM), and IL-11. There...
18 KB (2,202 words) - 01:16, 14 June 2024
growth factors and is frequently added to growth media used for eukaryotic cell culture. A combination of FBS and the cytokine leukemia inhibitory factor was...
7 KB (736 words) - 11:54, 31 July 2024
negative regulating factors are known (such as dopamine, leukemia inhibitory factor, some prostaglandins) but few stimulating factor. Its secretion is mediated...
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of clinical outcome and prognosis in pediatric core binding factor-acute myeloid leukemia]". Zhonghua Xue Ye Xue Za Zhi = Zhonghua Xueyexue Zazhi (in...
24 KB (2,872 words) - 06:27, 22 July 2024
Brain-derived neurotrophic factor (BDNF), or abrineurin, is a protein that, in humans, is encoded by the BDNF gene. BDNF is a member of the neurotrophin...
46 KB (5,344 words) - 17:28, 12 October 2024
RANKL (redirect from Osteoclast differentiation factor)
Receptor activator of nuclear factor kappa-Β ligand (RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), TNF-related activation-induced...
28 KB (3,309 words) - 05:21, 5 August 2024
F, et al. (2003). "Vascular endothelial growth factor and its receptors in multiple myeloma". Leukemia. 17 (10): 1961–6. doi:10.1038/sj.leu.2403076. PMID 14513045...
40 KB (4,578 words) - 12:30, 10 September 2024
Shew JY, Ho HN, Hsu WL, Yang YS (October 1999). "Expression of leukemia inhibitory factor and its receptor in preimplantation embryos". Fertil. Steril....
35 KB (3,965 words) - 16:19, 27 September 2024
album A Natural Death "Líf", a song by Hildur Vala Einarsdóttir Leukemia inhibitory factor, a cytokine that affects cell growth and development Laser-induced...
1 KB (189 words) - 22:31, 11 May 2024
Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
17 KB (1,708 words) - 22:30, 15 October 2024
Fibroblast growth factor 2 (FGF-2), also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by...
22 KB (2,698 words) - 17:05, 16 July 2024
Coupey L, et al. (1996). "Binding interactions of leukemia inhibitory factor and ciliary neurotrophic factor with the different subunits of their high affinity...
15 KB (1,748 words) - 16:47, 2 October 2024
Fibroblast growth factor 21 (FGF-21) is a protein that in mammals is encoded by the FGF21 gene. The protein encoded by this gene is a member of the fibroblast...
24 KB (3,038 words) - 18:36, 14 July 2024
Tyrosine kinase (section Chronic myeloid leukemia)
growth factor receptor (EGFR) mutation BCR-ABL is a constitutively activated tyrosine kinase that is associated with chronic myeloid leukemia. It is formed...
43 KB (5,251 words) - 10:44, 24 June 2024
neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF), and ciliary neurotrophic factor (CNTF). Although...
13 KB (1,177 words) - 02:19, 4 September 2024
of acidic amino acids located between the D1 and D2 domains has auto-inhibitory functions. This 'acid box' motif interacts with the heparan sulfate binding...
25 KB (3,124 words) - 21:38, 18 August 2024
lab with media containing serum and leukemia inhibitory factor or serum-free media supplements with two inhibitory drugs ("2i"), the MEK inhibitor PD03259010...
73 KB (8,675 words) - 11:53, 10 October 2024
Transforming growth factor ([attribution needed], or TGF) is used to describe two classes of polypeptide growth factors, TGFα and TGFβ. The name "Transforming...
6 KB (596 words) - 05:15, 1 January 2024
growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family...
60 KB (6,879 words) - 14:26, 16 July 2024
Imatinib (section Chronic myelogenous leukemia)
acute lymphoblastic leukemia (Ph+ ALL), myelodysplastic/myeloproliferative diseases associated with platelet-derived growth factor receptor gene rearrangements...
71 KB (6,702 words) - 05:32, 9 August 2024
used to treat certain cases of chronic myelogenous leukemia (CML) and acute lymphoblastic leukemia (ALL). Specifically it is used to treat cases that...
22 KB (1,994 words) - 04:41, 3 January 2024
Interleukin 6 (category Neurotrophic factors)
signal transducer for several cytokines including leukemia inhibitory factor (LIF), ciliary neurotropic factor, oncostatin M, IL-11 and cardiotrophin-1, and...
63 KB (7,473 words) - 05:58, 16 October 2024
Heinrich PC, Schaper F (2000). "Signal transduction of IL-6, leukemia-inhibitory factor, and oncostatin M: structural receptor requirements for signal...
16 KB (1,922 words) - 21:02, 8 November 2023
Filgrastim (category Growth factors)
are available. Filgrastim is used to treat neutropenia; acute myeloid leukemia; nonmyeloid malignancies; leukapheresis; congenital neutropenia‚ cyclic...
24 KB (1,710 words) - 19:18, 30 August 2024