• Leukotriene B4 (LTB4) is a leukotriene involved in inflammation. It has been shown to promote insulin resistance in obese mice. LTB4 is a leukotriene...
    4 KB (238 words) - 21:22, 13 April 2024
  • of vehicle armour Leukotriene B4 receptor and Leukotriene B4 receptor 2, two human genes Lipoxin B4, a lipoxin Proanthocyanidin B4, a B type proanthocyanidin...
    4 KB (511 words) - 17:27, 1 December 2024
  • Thumbnail for Leukotriene
    Leukotrienes are a family of eicosanoid inflammatory mediators produced in leukocytes by the oxidation of arachidonic acid (AA) and the essential fatty...
    18 KB (1,957 words) - 18:25, 30 March 2024
  • Thumbnail for Leukotriene B4 receptor 2
    Leukotriene B4 receptor 2, also known as BLT2, BLT2 receptor, and BLTR2, is an Integral membrane protein that is encoded by the LTB4R2 gene in humans and...
    51 KB (6,698 words) - 08:55, 29 September 2024
  • The leukotriene B4 receptors (BLTRs) include the following two receptors: Leukotriene B4 receptor 1 (BLTR1) Leukotriene B4 receptor 2 (BLTR2) Eicosanoid...
    464 bytes (27 words) - 16:40, 3 May 2022
  • Thumbnail for Leukotriene B4 receptor 1
    Leukotriene B4 receptor 1, also known as BLT1 or BLT1 receptor, is a protein that in humans is encoded by the LTB4R gene. Eicosanoid receptor Etalocib...
    7 KB (912 words) - 09:00, 29 September 2024
  • In enzymology, a leukotriene-B4 20-monooxygenase (EC 1.14.13.30) is an enzyme that catalyzes the chemical reaction (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6...
    3 KB (318 words) - 19:52, 26 August 2023
  • Thumbnail for Leukotriene A4
    Leukotriene A4 (LTA4) is a leukotriene, and is the precursor for the productions of leukotriene B4 (LTB4) and leukotriene C4 (LTC4). Following the biosynthesis...
    7 KB (449 words) - 17:04, 30 March 2024
  • proteins: Leukotriene B4 receptors (BLTRs) – bind to and are activated by LTB4: BLT1 (Leukotriene B4 receptor 1) – LTB4R BLT2 (Leukotriene B4 receptor...
    2 KB (156 words) - 16:40, 3 May 2022
  • Thumbnail for CYP4F3
    Both variants localize on the endoplasmic reticulum and metabolize leukotriene B4 and very likely 5-hydroxyeicosatetraenoic acid, 5-oxo-eicosatetraenoic...
    11 KB (1,316 words) - 23:53, 23 May 2024
  • ligand that each binds: Leukotrienes: BLT1 (Leukotriene B4 receptor) – LTB4R; BLT1 is the primary receptor for leukotriene B4. Relative potencies in binding...
    24 KB (2,893 words) - 07:17, 15 May 2024
  • Thumbnail for CYP4F2
    enzyme, its primary substrate (molecule upon which an enzyme acts) is leukotriene B4 (LTB4), an eicosanoid, which is an inflammatory mediator. By hydroxylating...
    80 KB (8,986 words) - 23:34, 29 December 2024
  • Thumbnail for Arachidonic acid 5-hydroperoxide
    a) leukotriene A4 which is then metabolized to the chemotactic factor for leukocytes, leukotriene B4, or to contractors of lung airways, leukotriene C4...
    3 KB (160 words) - 21:43, 1 April 2024
  • Thumbnail for Leukotriene-A4 hydrolase
    Leukotriene-A4 hydrolase is an enzyme that catalyzes the reaction which converts Leukotriene A4 to Leukotriene B4. It is a bifunctional zinc enzyme (EC...
    6 KB (595 words) - 08:01, 19 April 2024
  • Thumbnail for Neutrophil
    following chemical signals such as interleukin-8 (IL-8), C5a, fMLP, leukotriene B4, and hydrogen peroxide (H2O2) in a process called chemotaxis. They are...
    55 KB (5,864 words) - 19:36, 25 December 2024
  • Thumbnail for Type I hypersensitivity
    mediators from arachidonic acid; some of these mediators include histamine, leukotriene (LTC4 and LTD4 and LTB4), and prostaglandin, which act on proteins (e...
    9 KB (840 words) - 13:07, 15 March 2024
  • Thumbnail for Monooxygenase
    activate signaling molecules for example by hydroxylating leukotriene B4 to 20-hydroxy-leukotriene B5, 5-hydroxyeicosatetraenoic acid to 5,20-dihydroxyeicosatetraenoic...
    3 KB (285 words) - 09:23, 18 August 2023
  • Thumbnail for Ketoprofen
    2 mg/kg/day. Studies have shown that it does not inhibit 5-lipoxygenase and leukotriene B4, as originally claimed. It is therefore not considered superior to phenylbutazone...
    18 KB (1,852 words) - 01:55, 20 September 2024
  • Thumbnail for Depside
    anti-proliferative activity in vitro. As inhibitors of prostaglandin synthesis and leukotriene B4 biosynthesis, some depsides have in vitro anti-inflammatory activity...
    6 KB (686 words) - 11:03, 23 February 2023
  • Thumbnail for Inflammation
    and serotonin, as well as eicosanoids such as prostaglandin E2 and leukotriene B4 to remodel the local vasculature. Macrophages and endothelial cells...
    96 KB (9,751 words) - 20:07, 29 December 2024
  • Thumbnail for Eosinophil
    5-hydroxyicosatetraenoic acid and 5-oxo-eicosatetraenoic acid, and certain leukotrienes like leukotriene B4 (LTB4) and MCP1/4. Interleukin-13, another TH2 cytokine, primes...
    29 KB (3,166 words) - 00:19, 9 September 2024
  • Thumbnail for Eicosanoid
    eicosanoids, including most prominently the prostaglandins, thromboxanes, leukotrienes, lipoxins, resolvins, and eoxins. For each subfamily, there is the potential...
    86 KB (9,651 words) - 06:41, 2 November 2024
  • Thumbnail for ALOX15
    along with 12(S)-HETE, activates the leukotriene B4 receptor, leukotriene B4 receptor 2 (BLT2) but not its leukotriene B4 receptor 1 (BLT1). This allows the...
    44 KB (5,708 words) - 18:03, 29 November 2024
  • Thumbnail for Ibuprofen
    Elafibranor Etomoxir Fenofibrate Genistein Gemfibrozil GW-7647 Lanifibranor Leukotriene B4 LG-101506 LG-100754 Lobeglitazone Muraglitazar Oleylethanolamide Palmitoylethanolamide...
    63 KB (5,978 words) - 18:04, 4 December 2024
  • Thumbnail for Chemotaxis
    5-lipoxygenase). Their most prominent member with chemotactic factor activity is leukotriene B4, which elicits adhesion, chemotaxis, and aggregation of leukocytes....
    66 KB (7,443 words) - 22:25, 29 September 2024
  • Thumbnail for Chamazulene
    ER; Ammon, HP (1994). "Chamazulene: An antioxidant-type inhibitor of leukotriene B4 formation". Planta Medica. 60 (5): 410–3. doi:10.1055/s-2006-959520...
    2 KB (97 words) - 20:37, 1 August 2021
  • Thumbnail for Fenofibrate
    Elafibranor Etomoxir Fenofibrate Genistein Gemfibrozil GW-7647 Lanifibranor Leukotriene B4 LG-101506 LG-100754 Lobeglitazone Muraglitazar Oleylethanolamide Palmitoylethanolamide...
    26 KB (2,514 words) - 06:51, 30 December 2024
  • Thumbnail for Berberine
    Elafibranor Etomoxir Fenofibrate Genistein Gemfibrozil GW-7647 Lanifibranor Leukotriene B4 LG-101506 LG-100754 Lobeglitazone Muraglitazar Oleylethanolamide Palmitoylethanolamide...
    11 KB (877 words) - 23:53, 27 December 2024
  • Thumbnail for Monocyte
    chemotactic protein-3 (CCL7); certain arachidonic acid metabolites such as leukotriene B4 and members of the 5-hydroxyicosatetraenoic acid and 5-oxo-eicosatetraenoic...
    31 KB (3,227 words) - 02:17, 22 December 2024
  • metabolism of certain bioactive arachidonic acid metabolites such as leukotriene B4 and 5-hydroxyicosatetraenoic acid produces 20-hydroxylated products...
    11 KB (758 words) - 22:34, 18 October 2024