The liver X receptor (LXR) is a member of the nuclear receptor family of transcription factors and is closely related to nuclear receptors such as the...
26 KB (3,038 words) - 01:37, 11 December 2023
Liver X receptor beta (LXR-β) is a member of the nuclear receptor family of transcription factors. LXR-β is encoded by the NR1H2 gene (nuclear receptor...
10 KB (1,201 words) - 17:34, 13 June 2022
Liver X receptor alpha (LXR-alpha) is a nuclear receptor protein that in humans is encoded by the NR1H3 gene (nuclear receptor subfamily 1, group H, member...
14 KB (1,641 words) - 03:02, 20 June 2024
acid receptor (BAR), also known as farnesoid X receptor (FXR) or NR1H4 (nuclear receptor subfamily 1, group H, member 4), is a nuclear receptor that is...
17 KB (1,945 words) - 06:12, 13 July 2024
Y (18 February 2016). "Liver X receptor α is essential for the capillarization of liver sinusoidal endothelial cells in liver injury". Scientific Reports...
5 KB (543 words) - 15:38, 8 May 2024
The liver receptor homolog-1 (LRH-1) also known as totipotency pioneer factor NR5A2 (nuclear receptor subfamily 5, group A, member 2) is a protein that...
13 KB (1,418 words) - 23:09, 13 June 2024
Obeticholic acid (category Farnesoid X receptor agonists)
six weeks reduced markers of liver inflammation and fibrosis and increased insulin sensitivity. The Farnesoid X Receptor Ligand Obeticholic Acid in Nonalcoholic...
19 KB (1,825 words) - 22:02, 12 July 2024
Webb P, Gustafsson JA (March 2014). "Structure of the retinoid X receptor α-liver X receptor β (RXRα-LXRβ) heterodimer on DNA". Nature Structural & Molecular...
74 KB (6,675 words) - 18:09, 20 June 2024
NR1I receptors: constitutive androstane receptor, pregnene X receptor, farnesoid X receptor alpha, farnesoid X receptor beta, liver X receptor alpha...
22 KB (2,646 words) - 05:40, 13 July 2024
Bile acid (category Farnesoid X receptor agonists)
"Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine". Journal of Lipid Research. 48 (12): 2664–72. doi:10...
36 KB (4,587 words) - 11:12, 7 July 2024
estrogen receptor modulator (SERM) (a mixed, tissue-specific agonist-antagonist of the estrogen receptor (ER)) and as an agonist of the liver X receptor (LXR)...
3 KB (244 words) - 04:27, 19 December 2023
dysfunction–associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), is a type of chronic liver disease. This condition...
132 KB (14,752 words) - 20:35, 22 July 2024
"Interleukin-1 family cytokines in liver diseases." Mediators of inflammation 2015 (2015). Fowler, Ashley J., et al. "Liver X receptor activators display anti-inflammatory...
13 KB (1,788 words) - 20:46, 9 June 2020
Cirrhosis (redirect from Liver cirrhosis)
Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, and end-stage liver disease, is a condition of the liver in which the normal functioning...
112 KB (11,527 words) - 13:18, 22 July 2024
(SREBP-1c) in response to feeding/insulin in living animals. Although liver X receptors (LXRs) modulate the expression of sterol regulatory element binding...
35 KB (4,020 words) - 10:13, 27 March 2024
acid receptor, both of which are activated by bile acids. Adopted orphan receptors in the nuclear receptor group include FXR, liver X receptor (LXR)...
7 KB (737 words) - 08:12, 21 March 2024
the precursor to the steroid hormones. It is an agonist of the liver X receptor. 20α,22R-Dihydroxycholesterol 27-Hydroxycholesterol CHAUDHURI AC, HARADA...
3 KB (186 words) - 16:33, 26 April 2023
Chenodeoxycholic acid (category Farnesoid X receptor agonists)
potent natural bile acid at stimulating the nuclear bile acid receptor, farnesoid X receptor (FXR). The transcription of many genes is activated by FXR,...
10 KB (836 words) - 19:53, 29 June 2024
transport of fatty acids from adipose tissue to the liver is increased. Impairment or inhibition of receptor molecules (PPAR-α, PPAR-γ and SREBP1) that control...
38 KB (3,896 words) - 13:25, 18 May 2024
Retinoid X receptor alpha (RXR-alpha), also known as NR2B1 (nuclear receptor subfamily 2, group B, member 1) is a nuclear receptor that in humans is encoded...
25 KB (2,892 words) - 21:07, 15 November 2023
biology, the pregnane X receptor (PXR), also known as the steroid and xenobiotic sensing nuclear receptor (SXR) or nuclear receptor subfamily 1, group I...
17 KB (1,978 words) - 10:10, 15 May 2024
Ivermectin (category GABAA receptor positive allosteric modulators)
(December 2016). "Bile Acid Nuclear Receptor Farnesoid X Receptor: Therapeutic Target for Nonalcoholic Fatty Liver Disease". Endocrinology and Metabolism...
79 KB (7,768 words) - 04:56, 3 July 2024
inhibitors, have been shown to effectively kill cancer cells. Activated liver X receptor (LXR) forms a complex with corepressors to suppress the inflammatory...
24 KB (2,462 words) - 05:39, 27 May 2024
MYLIP (redirect from Increased Degradation of LDL Receptor Protein)
sterol-activated liver X receptor. Increased Degradation of LDL Receptor Protein (IDOL) is a ubiquitin ligase that ubiquinates LDL receptors in endosomes...
6 KB (744 words) - 06:10, 27 May 2024
"Liver X receptors (LXR) as therapeutic targets in dyslipidemia". Cardiovascular Therapeutics. 26 (4): 297–316. doi:10.1111/j.1755-5922.2008.00062.x....
71 KB (7,373 words) - 05:37, 2 July 2024
Authority - statutory authority in Victoria, Australia Liver X receptor alpha - a nuclear receptor protein in humans This disambiguation page lists articles...
189 bytes (54 words) - 01:25, 25 January 2016
Blackstone Group. Air Luxor (ICAO code), a former airline Liver X receptor, a member of the nuclear receptor family of transcription factors Luxor International...
400 bytes (83 words) - 11:50, 3 September 2021
In liver FGF21 expression is regulated by PPARα and levels rise substantially with both fasting and consumption of ketogenic diets. Liver X receptor (LXR)...
24 KB (3,038 words) - 18:36, 14 July 2024
(2008). "p75 Neurotrophin receptor is a marker for precursors of stellate cells and portal fibroblasts in mouse fetal liver". Gastroenterology. 135 (1):...
86 KB (10,225 words) - 20:51, 15 July 2024
phosphorylation-dephosphorylation. CYP7A1 is upregulated by the nuclear receptor LXR (liver X receptor) when cholesterol (to be specific, oxysterol) levels are high...
22 KB (2,695 words) - 03:33, 10 March 2024