• Thumbnail for MCM4
    DNA replication licensing factor MCM4 is a protein that in humans is encoded by the MCM4 gene. The protein encoded by this gene is one of the highly conserved...
    11 KB (1,256 words) - 16:47, 14 August 2023
  • Thumbnail for MCM6
    Hanaoka F (November 2002). "Roles of Mcm7 and Mcm4 subunits in the DNA helicase activity of the mouse Mcm4/6/7 complex". J. Biol. Chem. 277 (45): 42471–9...
    14 KB (1,681 words) - 07:37, 31 August 2023
  • Thumbnail for DNA replication
    ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand...
    60 KB (7,286 words) - 08:26, 2 July 2024
  • Thumbnail for PABCO Transit
    Route Terminal A Major streets Terminal B History MCM4 Morristown, or Morris Township Honeywell (to AM, from PM) Routes 510 and 513, via Chester Chester...
    9 KB (301 words) - 21:09, 18 June 2023
  • Thumbnail for MCM2
    other DNA replication-related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex...
    13 KB (1,600 words) - 02:11, 3 December 2023
  • Thumbnail for Eukaryotic DNA replication
    DNA-bound MCM-DH, contacting Mcm2 of one hexamer and Mcm4/6 of the opposite hexamer. Mcm2, Mcm4 and Mcm6 are all substrates of phosphorylation by DDK...
    119 KB (14,646 words) - 22:02, 3 July 2024
  • Thumbnail for Origin of replication
    ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand...
    113 KB (12,561 words) - 17:02, 14 May 2024
  • GATA-binding factor 2 (a transcription factor), and MCM4 encoding the DNA replication licensing factor, MCM4. 4) Inflammatory/autoimmune diseases such as chronic...
    140 KB (16,977 words) - 09:07, 9 September 2024
  • HGNC:6944 P49736 9355 MCM3 HGNC:6945 P25205 9356 MCM3AP HGNC:6946 O60318 9357 MCM4 HGNC:6947 P33991 9358 MCM5 HGNC:6948 P33992 9359 MCM6 HGNC:6949 Q14566 9360...
    277 KB (17 words) - 15:46, 9 May 2024
  • Cdt1/RLF-B Mcm2 Mcm2/Cdc19/Nda1 Mcm2 Mcm2 Mcm3 Mcm3 Mcm3 Mcm3 Cdc54/Mcm4 Cdc21 DPA Mcm4 Cdc46/Mcm5 Mcm5/Nda4 Mcm5 Mcm5 Mcm6 Mcm6/Mis5 Mcm6 Mcm6 Cdc47/Mcm7...
    21 KB (2,335 words) - 13:22, 16 August 2023
  • ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand...
    6 KB (634 words) - 22:52, 2 December 2023
  • Thumbnail for Minichromosome maintenance
    mutants were mcm1, mcm2, mcm3, mcm5 and mcm10. Later on, others identified Mcm4, Mcm6 and Mcm7 in yeasts and other eukaryotes based on homology to Mcm2p...
    24 KB (3,042 words) - 22:16, 29 October 2022
  • Thumbnail for Morristown, New Jersey
    routes, replacing service that had been offered on the MCM1, MCM2, MCM3, MCM4, MCM8 and MCM10 routes until 2010, when subsidies to the local provider were...
    165 KB (18,026 words) - 14:54, 30 August 2024
  • assembled on DNA. Finally, his laboratory was also the first to identify MCM4 as a cellular licensing factor, a replication step that is potentially altered...
    3 KB (357 words) - 11:39, 26 April 2024
  • Thumbnail for Stress granule
    MBNL2 MBNL2 Muscleblind Like Splicing Regulator 2 MCM4 MCM4 DNA replication licensing factor MCM4 MCM5 MCM5 DNA replication licensing factor MCM5 MCM7...
    183 KB (12,458 words) - 20:40, 1 July 2024
  • ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand...
    3 KB (336 words) - 09:50, 4 November 2023
  • Thumbnail for MCM7
    protein CDC6, Cell division cycle 7-related protein kinase, DBF4, MCM2, MCM3, MCM4, MCM5, MCM6, MNAT1, ORC1L, ORC2L, ORC3L, ORC5L, Replication protein A1, Retinoblastoma...
    14 KB (1,647 words) - 21:46, 18 August 2023
  • Thumbnail for Chester Borough, New Jersey
    S. Route 206 intersect. NJ Transit local bus service was provided on the MCM4 and MCM5 routes until June 2010, when NJ Transit pulled the subsidy. Chester...
    50 KB (5,641 words) - 23:45, 22 May 2024
  • Thumbnail for Bik Kwoon Tye
    R. J., Hartford, S. A., Tye, B. K. & Schimenti, J. C. A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice. Nat Genet...
    17 KB (2,058 words) - 16:31, 19 May 2024
  • Thumbnail for Mendham Township, New Jersey
    Interstate 78, are all accessible nearby. NJ Transit offered service on the MCM4 and MCM5 routes until 2010, when subsidies to the local provider were eliminated...
    66 KB (7,062 words) - 01:10, 8 August 2024
  • Thumbnail for Chester Township, New Jersey
    Interstate 78 in Bedminster. NJ Transit local bus service was provided on the MCM4 and MCM5 routes until June 2010, when NJ Transit pulled the subsidy. People...
    63 KB (6,898 words) - 23:47, 22 May 2024
  • Thumbnail for MCM8
    the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and...
    8 KB (911 words) - 02:11, 3 December 2023
  • (ICF1, 2, 3, and 4) PMS2 deficiency RIDDLE syndrome (RNF168 deficiency) MCM4 deficiency FILS syndrome (POLE deficiency) POLE2 deficiency LIG1 deficiency...
    19 KB (1,836 words) - 09:52, 5 July 2024
  • Thumbnail for Morris Township, New Jersey
    routes, replacing service that had been offered on the MCM1, MCM2, MCM3, MCM4, MCM8 and MCM10 routes until 2010, when subsidies to the local provider were...
    66 KB (7,228 words) - 06:11, 28 July 2024
  • Thumbnail for POLD3
    ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand...
    6 KB (740 words) - 17:22, 3 December 2023
  • Thumbnail for CDC45-related protein
    Tanaka T, Kobayashi T, Tamai K, Ohtani K, Arai K (2006). "Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin"....
    9 KB (1,112 words) - 07:03, 8 November 2023
  • Thumbnail for Mendham Borough, New Jersey
    County Route 510 and County Route 525. NJ Transit offered service on the MCM4 and MCM5 routes until 2010, when subsidies to the local provider were eliminated...
    64 KB (7,040 words) - 22:28, 13 September 2024
  • Thumbnail for DNA polymerase alpha catalytic subunit
    DNA dependent polymerase alpha (Pol α) has been shown to interact with MCM4 and GINS1, Retinoblastoma protein, PARP1 and RBMS1. DNA Polymerase DNA polymerase...
    15 KB (1,768 words) - 11:44, 18 August 2023
  • Thumbnail for Replication protein A1
    Replication protein A1 has been shown to interact with: BRCA2, BLM, MCM2, MCM4, MCM6, MCM7, MUTYH, ORC2L, ORC6L, P53, RPA2, RPA3, TIPIN, TP53BP1, and XPA...
    13 KB (1,549 words) - 16:10, 4 January 2024
  • Thumbnail for ORC1
    division cycle 7-related protein kinase, Cyclin-dependent kinase 2, MCM2, MCM4, MCM6, MCM7, MYST2, ORC2, ORC4, ORC5, and SKP2. GRCh38: Ensembl release 89:...
    12 KB (1,433 words) - 06:31, 27 December 2023