protein 8 (mLST8) or TORC subunit LST8 or G protein beta subunit-like (GβL or Gable), is a protein that in humans is encoded by the MLST8 (MTOR associated...

the S1859 site downstream of mTORC1 signaling. CAD is also regulated by mLST8, an mTORC1/2 component. Congenital disorder of glycosylation, Type Iz is...

regulatory-associated protein of mTOR (Raptor), mammalian lethal with SEC13 protein 8 (mLST8) and the non-core components PRAS40 and DEPTOR. This complex functions as...

HGNC:7141 P12872 9639 MLNR HGNC:4495 O43193 9640 MLPH HGNC:29643 Q9BV36 9641 MLST8 HGNC:24825 Q9BVC4 9642 MLX HGNC:11645 Q9UH92 9643 MLXIP HGNC:17055 Q9HAP2...

mTOR-interacting protein (DEPTOR), mammalian lethal with sec-13 protein 8 (mLST8, also known as GβL), and TTI1/TEL2 complex are shared by both mTORC2 and...

mammalian LST8 (mLST8), and two negative regulators, proline-rich AKT substrate 40 (PRAS40) and DEPTOR. mTORC2 consists of mTOR, mLST8, mSin1, protor,...

as raptor), mammalian lethal[clarification needed] with SEC13 protein 8 (MLST8), PRAS40 and DEPTOR. This complex embodies the classic functions of mTOR...

12325. PMC 4406678. PMID 25678027. Lu, A (2016). "Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum". Nature Communications...

Crimmins EM, Lunnon K, et al. (February 2016). "Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum". Nature Communications...

binds rapamycin. In addition to mTOR, the TORC2 complex contains RICTOR, mLST8, and SIN1 and regulates insulin action and Akt phosphorylation. Thus, mTOR...

mammalian target of rapamycin complex 1 (mTORC1). This complex contains mTOR, MLST8, RPTOR, AKT1S1/PRAS40, and DEPTOR. mTORC1 both binds to and is inhibited...