• Thumbnail for Mad1
    Mad1 is a non-essential protein which in yeast has a function in the spindle assembly checkpoint (SAC). This checkpoint monitors chromosome attachment...
    10 KB (1,197 words) - 15:41, 12 April 2024
  • Thumbnail for Kinetochore
    Mad1, Mad2 and dynein on kinetochores (<10-15% in relation to unattached kinetochores). However, if both Ndc80/Hec1 and Nuf2 levels are reduced, Mad1...
    65 KB (7,839 words) - 18:06, 1 July 2024
  • Thumbnail for Spindle checkpoint
    kinetochores first bind to a MAD1-C-MAD2-p31comet complex and releases the p31comet through unknown mechanisms. The resulting MAD1-C-MAD2 complex recruits...
    73 KB (9,145 words) - 07:11, 31 August 2024
  • is activated, Mad2 binds Mad1 to form Closed-Mad2-Mad1 complexes. Given that Mad1:Mad2 is a stable complex and Cdc20 and Mad1 bind Mad 2 in the very same...
    10 KB (1,150 words) - 15:42, 12 April 2024
  • Thumbnail for Lucca Allen
    1 BUR1 3 3 BUR1 4 1 BUR2 1 1 BUR2 2 Ret BUR2 3 9 BUR2 4 1 MAD1 1 3 MAD1 2 6 MAD1 3 4 MAD1 4 2 MAD2 1 7 MAD2 2 5 MAD2 3 1 MAD2 4 1 SEP3 1 4 SEP3 2 3 SEP3...
    27 KB (558 words) - 16:50, 2 September 2024
  • Thumbnail for HORMA domain
    HORMA domain crystal structure of mad1-mad2 reveals a conserved mad2 binding motif in mad1 and cdc20. Identifiers Symbol HORMA Pfam PF02301 InterPro IPR003511...
    2 KB (202 words) - 14:31, 7 June 2023
  • MAD Symposium (section MAD1)
    27th and 28th of August, 2011. The theme of the symposium was "vegetation." MAD1 Speakers: Alex Atala — Chef, Brazil Tør Norretranders — Writer, Denmark Miles...
    9 KB (962 words) - 11:44, 27 December 2023
  • Thumbnail for MLX (gene)
    association with a subset of the Mad family of transcriptional repressors, namely Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms...
    8 KB (974 words) - 07:48, 29 December 2023
  • Pos Driver MAD1 CHE MAD2 KAR TBC Pts R1 R2 R3 R1 R2 R1 R2 R3 R4 R1 R2 R3 R1 R2 R3 1 Aqil Alibhai 2 6 2 DNS 1 2 84 2 Hugh Barter Ret 1 1 1 5 81 3 Jaden...
    21 KB (1,054 words) - 12:32, 14 September 2024
  • beijingdou (Josh Ong), JerseyBorn (Sean Semola), tropoFarmer, ElectionDayMad1 and KingKhah (AJ Khah) Kingpins     Jamal Anderson, SPOTTIE WIFI, Dr. Leo...
    27 KB (2,508 words) - 05:49, 3 September 2024
  • Thumbnail for MAD1L1
    Mitotic spindle assembly checkpoint protein MAD1 is a protein that in humans is encoded by the MAD1L1 gene. MAD1L1 is also known as Human Accelerated Region...
    8 KB (644 words) - 00:00, 3 December 2023
  • Thumbnail for Duane Eddy
    Eddy & The Rebels - - Capitol ST-12567 2011 Road Trip - 116 Mad Monkey/EMI MAD1 "—" denotes a recording that did not chart or was not released in that territory...
    55 KB (3,651 words) - 18:36, 2 September 2024
  • Thumbnail for Andrea Musacchio
    views on protein functions in living cells. He is best known for his work on Mad1/Mad2 complexes, which led to the formulation of the template model, and for...
    12 KB (1,151 words) - 03:41, 4 July 2024
  • Thumbnail for SIN3A
    Cowley SM, Laherty CD, Eisenman RN, Radhakrishnan I (August 2004). "HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations"...
    28 KB (3,124 words) - 14:11, 22 December 2023
  • Thumbnail for Elias Seppänen
    2 3 BUR1 3 2 BUR1 4 2 BUR2 1 4 BUR2 2 3 BUR2 3 3 BUR2 4 3 MAD1 1 1 MAD1 2 5 MAD1 3 1 MAD1 4 1 MAD2 1 2 MAD2 2 1 MAD2 3 4 MAD2 4 3 SEP3 1 3 SEP3 2 5 SEP3...
    24 KB (781 words) - 16:40, 20 June 2024
  • Thumbnail for MAD2L1
    interact with: ADAM17, BUB1B, CDC20, CDC27 and Estrogen receptor beta, MAD2L2, Mad1, and UBD. GRCh38: Ensembl release 89: ENSG00000164109 – Ensembl, May 2017...
    16 KB (1,975 words) - 22:35, 3 March 2023
  • Thumbnail for NDC80
    "Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2". Science. 297 (5590): 2267–70. Bibcode:2002Sci...297.2267M. doi:10...
    10 KB (1,178 words) - 15:32, 6 April 2024
  • beijingdou (Josh Ong), JerseyBorn (Sean Semola), tropoFarmer, ElectionDayMad1 and KingKhah (AJ Khah) Kingpins     Jamal Anderson, SPOTTIE WIFI, Dr. Leo...
    13 KB (684 words) - 18:29, 11 August 2023
  • shares and Renault SAS. In addition to an initial investment in 2008-2009 of MAD1 billion of loans contracted from Moroccan banks, the factory was financed...
    9 KB (737 words) - 16:25, 16 August 2024
  • Thumbnail for BUB1
    recruitment of BubR1, Mad1 and Mad2. Upon spindle damage Bub1 is also triggered to phosphorylate Mad1 leading to dissociation of the Mad1-Mad2 complex and...
    18 KB (2,228 words) - 10:55, 10 May 2023
  • P2004, 1981) Live in a Room! EP (Press Records, 1982) Little Figures 2 x LP (MAD1 - Armageddon Records, 1981) Little Figures 1 x LP (Press Records, 1982) Luxury...
    2 KB (191 words) - 20:00, 5 February 2024
  • Thumbnail for Schmidtea mediterranea
    genes, including genes responsible for the synthesis of fatty acids and the MAD1 and MAD2 genes, which were thought to be essential components of the spindle...
    6 KB (600 words) - 19:31, 20 December 2023
  • Thumbnail for SIN3B
    AM, Jansen JF, Vermeulen M, Stunnenberg HG, Vuister GW (Dec 2000). "The Mad1-Sin3B interaction involves a novel helical fold". Nature Structural Biology...
    9 KB (1,106 words) - 02:57, 19 February 2024
  • Pos Driver SEP1 SEP2 MAD1 MAD2 CHA1 CHA2 SEP3 SEP4 Pts 1 Alessandro Ghiretti 1 6 2 2 1 Ret 1 1 3 1 2 2 1 1 1 1 1 4 1 1 1 1 2 2 446 2 Kane Shepherd 3 1...
    20 KB (221 words) - 20:28, 7 December 2023
  • Thumbnail for EIF4EBP1
    PMID 10022874. Seeley TW, Wang L, Zhen JY (1999). "Phosphorylation of human MAD1 by the BUB1 kinase in vitro". Biochem. Biophys. Res. Commun. 257 (2): 589–595...
    22 KB (2,696 words) - 01:25, 29 March 2024
  • Thumbnail for BUB3
    proteins which regulate the cell arrest are BUB1, BUB2, BUB3 (this protein), Mad1, Mad2, Mad3 and MPS1. At unattached kinetochores, a complex consisting of...
    17 KB (2,197 words) - 00:05, 3 January 2024
  • Pos Driver SEP1 SEP2 BUR1 BUR2 MAD1 MAD2 SEP3 SEP4 SEP5 SEP6 Pts R1 R2 R3 R4 R1 R2 R3 R4 R1 R2 R3 R4 R1 R2 R3 R4 R1 R2 R3 R4 R1 R2 R3 R4 R1 R2 R3 R4 R1...
    36 KB (354 words) - 00:04, 17 July 2024
  • Thumbnail for NEK2
    Dou Z, Ahmed K, Wang H, Hu J, Wang Y, Yao X (2004). "NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signaling"...
    9 KB (1,182 words) - 23:52, 12 September 2024
  • Thumbnail for PINX1
    with lymph node metastasis Suppression of telomerase activity mediated by Mad1/c-Myc pathway Esophageal Over-expression of PINX1 inhibited cell growth,...
    23 KB (2,576 words) - 03:38, 17 June 2024
  • symbols of u, ü, and å are put in different places: ç& ru, è& rü, [null ä{"] [MAD1] då, ô$ hå. The viräma ( ,) is a small oblique stroke, placed at the foot...
    47 KB (4,864 words) - 14:23, 3 April 2024