Macrolides are a class of mostly natural products with a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine...
25 KB (2,795 words) - 02:37, 7 November 2024
Azithromycin (category Macrolide antibiotics)
confirmed, but it is likely safe. Azithromycin is an azalide, a type of macrolide antibiotic. It works by decreasing the production of protein, thereby...
62 KB (5,600 words) - 19:30, 19 October 2024
increasingly common. Resistance to multiple antibiotics, including the macrolide azithromycin, which until recently was the most reliable treatment, is...
45 KB (4,970 words) - 16:04, 9 October 2024
phenotype known as iMLSB. This phenotype of bacteria are resistant to the macrolide-lincosamide-streptogramin B group of antibiotics, however, the resistance...
44 KB (4,070 words) - 09:07, 18 October 2024
Erythromycin (category Macrolide antibiotics)
also applies if taken directly by the baby during this age. It is in the macrolide family of antibiotics and works by decreasing bacterial protein production...
42 KB (3,900 words) - 21:05, 19 October 2024
One important application are the many macrocyclic antibiotics, the macrolides, e.g. clarithromycin. Many metallocofactors are bound to macrocyclic ligands...
27 KB (3,288 words) - 22:37, 24 August 2024
complexes, including macrolides, tetracycline, ketolides, and fluoroquinolone, many of which can be administered orally. Macrolides are capable of reducing...
18 KB (1,990 words) - 17:15, 13 October 2024
Clarithromycin (category Macrolide antibiotics)
been reported. It may cause harm if taken during pregnancy. It is in the macrolide class and works by slowing down bacterial protein synthesis. Clarithromycin...
29 KB (2,711 words) - 14:43, 22 October 2024
Altohyrtin A (category Macrolides)
Altohyrtin A (spongistatin 1, cinachyrolide A) is a polyether macrolide originally isolated from the Okinawan marine sponge Hyrtios altum by Kobayashi...
6 KB (406 words) - 18:44, 6 November 2024
fibrosis and COPD. Infections can be treated with oral antibiotics from the macrolide family, which work by inhibiting the Mycoplasma protein biosynthesis....
40 KB (4,385 words) - 07:33, 2 November 2024
In enzymology, a macrolide 2'-kinase (EC 2.7.1.136) is an enzyme that catalyzes the chemical reaction ATP + oleandomycin ⇌ {\displaystyle \rightleftharpoons...
1 KB (135 words) - 13:52, 11 January 2024
Rachel Fuller Brown and Elizabeth Lee Hazen. It was the first polyene macrolide antifungal. It is on the World Health Organization's List of Essential...
29 KB (2,615 words) - 04:10, 30 September 2024
Azalide (category Macrolide antibiotics)
a class of macrolide antibiotics that were originally manufactured in response to the poor acid stability exhibited by original macrolides (erythromycin)...
4 KB (366 words) - 08:32, 16 February 2024
Nargenicin (category Macrolide antibiotics)
Nargenicin (CP-47,444, CS-682) is a 28 carbon macrolide with a fused tricyclic core that has in addition a unique ether bridge. The polyketide antibiotic...
5 KB (432 words) - 16:46, 8 March 2023
but as an indicator it is not accurate enough to decide whether or not macrolide treatment should be used. The presence of chest pain in children with...
120 KB (12,708 words) - 19:06, 31 October 2024
either alone (mild to moderate severity disease) or in combination with a macrolide. The World Health Organization (WHO) recommends amoxicillin as first-line...
49 KB (4,490 words) - 02:36, 6 November 2024
Surotomycin (category Macrolides)
Surotomycin was an investigational oral antibiotic. This macrolide antibiotic was under investigation by Merck & Co (who acquired Cubist Pharmaceuticals)...
5 KB (153 words) - 18:55, 20 October 2024
their tonsils. A drug-resistant strain of scarlet fever, resistant to macrolide antibiotics such as erythromycin, but retaining drug-sensitivity to beta-lactam...
62 KB (6,699 words) - 01:23, 22 October 2024
the genus Saccharopolyspora. Saccharopolyspora erythraea produces the macrolide antibiotic erythromycin. Cytochrome P450 eryF (CYP107A1) originally from...
3 KB (297 words) - 11:54, 13 May 2024
formula C20H38O2. It is a cyclic ester or lactone, more specifically a macrolide. Eicosanolide is used by several species of bees (such as some of genera...
2 KB (183 words) - 20:49, 2 November 2024
cephalosporins, monobactams (aztreonam), aminoglycosides, quinolones, macrolides, chloramphenicol, folate antagonists, and carbapenems. The adjectives...
24 KB (2,445 words) - 22:33, 4 September 2024
to macrolide treatment have been isolated and found to possess mutations at the transferase binding pocket in the 23S ribosomal subunit. Macrolide-resistant...
20 KB (2,133 words) - 12:14, 20 November 2023
clarithromycin, or azithromycin are typically the recommended treatment. Newer macrolides are frequently recommended due to lower rates of side effects....
50 KB (4,848 words) - 04:11, 7 November 2024
minimal relief provided for asthma symptoms. Macrolide antibiotics, particularly the azalide macrolide azithromycin, are a recently added Global Initiative...
167 KB (18,029 words) - 17:59, 27 October 2024
such as certain anti-arrhythmics, anti-depressants, and quinolone or macrolide antibiotics. Another condition that promotes arrhythmias is Wolff-Parkinson-White...
125 KB (13,739 words) - 04:56, 2 November 2024
recommended. In those who are allergic to penicillin, cephalosporins or macrolides may be used. In children with frequent episodes of tonsillitis, tonsillectomy...
33 KB (3,336 words) - 13:13, 2 August 2024
Tacrolimus (category Macrolides)
the body's learned (or adaptive) immune response. Chemically, it is a macrolide lactone that was first discovered in 1987, from the fermentation broth...
43 KB (4,357 words) - 08:39, 29 October 2024
Ivermectin (category Macrolides)
Ivermectin is an antiparasitic drug. After its discovery in 1975, its first uses were in veterinary medicine to prevent and treat heartworm and acariasis...
79 KB (7,699 words) - 17:51, 9 October 2024
lead to asthma. Macrolide antibiotic treatment can improve asthma in a subgroup of patients that remains to be clearly defined. Macrolide benefits were...
23 KB (2,610 words) - 01:54, 15 October 2024
Amino-penicillin Anti-pseudomonal BL−BLI Carbapenems Fluoro-quinolones Macrolide MDR & XDR Meticillin Mono INH Mono RIF Penicillin TMP-SMX Vancomycin Total...
42 KB (4,195 words) - 03:15, 3 October 2024