• Thumbnail for Macrolide
    Macrolides are a class of mostly natural products with a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine...
    25 KB (2,795 words) - 02:37, 7 November 2024
  • Thumbnail for Azithromycin
    Azithromycin (category Macrolide antibiotics)
    confirmed, but it is likely safe. Azithromycin is an azalide, a type of macrolide antibiotic. It works by decreasing the production of protein, thereby...
    62 KB (5,600 words) - 19:30, 19 October 2024
  • Thumbnail for Mycoplasma genitalium
    increasingly common. Resistance to multiple antibiotics, including the macrolide azithromycin, which until recently was the most reliable treatment, is...
    45 KB (4,970 words) - 16:04, 9 October 2024
  • Thumbnail for Clindamycin
    phenotype known as iMLSB. This phenotype of bacteria are resistant to the macrolide-lincosamide-streptogramin B group of antibiotics, however, the resistance...
    44 KB (4,070 words) - 09:07, 18 October 2024
  • Thumbnail for Erythromycin
    Erythromycin (category Macrolide antibiotics)
    also applies if taken directly by the baby during this age. It is in the macrolide family of antibiotics and works by decreasing bacterial protein production...
    42 KB (3,900 words) - 21:05, 19 October 2024
  • Thumbnail for Macrocycle
    One important application are the many macrocyclic antibiotics, the macrolides, e.g. clarithromycin. Many metallocofactors are bound to macrocyclic ligands...
    27 KB (3,288 words) - 22:37, 24 August 2024
  • complexes, including macrolides, tetracycline, ketolides, and fluoroquinolone, many of which can be administered orally. Macrolides are capable of reducing...
    18 KB (1,990 words) - 17:15, 13 October 2024
  • Thumbnail for Clarithromycin
    Clarithromycin (category Macrolide antibiotics)
    been reported. It may cause harm if taken during pregnancy. It is in the macrolide class and works by slowing down bacterial protein synthesis. Clarithromycin...
    29 KB (2,711 words) - 14:43, 22 October 2024
  • Thumbnail for Altohyrtin A
    Altohyrtin A (category Macrolides)
    Altohyrtin A (spongistatin 1, cinachyrolide A) is a polyether macrolide originally isolated from the Okinawan marine sponge Hyrtios altum by Kobayashi...
    6 KB (406 words) - 18:44, 6 November 2024
  • fibrosis and COPD. Infections can be treated with oral antibiotics from the macrolide family, which work by inhibiting the Mycoplasma protein biosynthesis....
    40 KB (4,385 words) - 07:33, 2 November 2024
  • In enzymology, a macrolide 2'-kinase (EC 2.7.1.136) is an enzyme that catalyzes the chemical reaction ATP + oleandomycin ⇌ {\displaystyle \rightleftharpoons...
    1 KB (135 words) - 13:52, 11 January 2024
  • Thumbnail for Nystatin
    Rachel Fuller Brown and Elizabeth Lee Hazen. It was the first polyene macrolide antifungal. It is on the World Health Organization's List of Essential...
    29 KB (2,615 words) - 04:10, 30 September 2024
  • Thumbnail for Azalide
    Azalide (category Macrolide antibiotics)
    a class of macrolide antibiotics that were originally manufactured in response to the poor acid stability exhibited by original macrolides (erythromycin)...
    4 KB (366 words) - 08:32, 16 February 2024
  • Thumbnail for Nargenicin
    Nargenicin (category Macrolide antibiotics)
    Nargenicin (CP-47,444, CS-682) is a 28 carbon macrolide with a fused tricyclic core that has in addition a unique ether bridge. The polyketide antibiotic...
    5 KB (432 words) - 16:46, 8 March 2023
  • Thumbnail for Pneumonia
    but as an indicator it is not accurate enough to decide whether or not macrolide treatment should be used. The presence of chest pain in children with...
    120 KB (12,708 words) - 19:06, 31 October 2024
  • Thumbnail for Amoxicillin
    either alone (mild to moderate severity disease) or in combination with a macrolide. The World Health Organization (WHO) recommends amoxicillin as first-line...
    49 KB (4,490 words) - 02:36, 6 November 2024
  • Thumbnail for Surotomycin
    Surotomycin (category Macrolides)
    Surotomycin was an investigational oral antibiotic. This macrolide antibiotic was under investigation by Merck & Co (who acquired Cubist Pharmaceuticals)...
    5 KB (153 words) - 18:55, 20 October 2024
  • Thumbnail for Scarlet fever
    their tonsils. A drug-resistant strain of scarlet fever, resistant to macrolide antibiotics such as erythromycin, but retaining drug-sensitivity to beta-lactam...
    62 KB (6,699 words) - 01:23, 22 October 2024
  • Thumbnail for Saccharopolyspora erythraea
    the genus Saccharopolyspora. Saccharopolyspora erythraea produces the macrolide antibiotic erythromycin. Cytochrome P450 eryF (CYP107A1) originally from...
    3 KB (297 words) - 11:54, 13 May 2024
  • Thumbnail for Eicosanolide
    formula C20H38O2. It is a cyclic ester or lactone, more specifically a macrolide. Eicosanolide is used by several species of bees (such as some of genera...
    2 KB (183 words) - 20:49, 2 November 2024
  • Thumbnail for Gram-negative bacteria
    cephalosporins, monobactams (aztreonam), aminoglycosides, quinolones, macrolides, chloramphenicol, folate antagonists, and carbapenems. The adjectives...
    24 KB (2,445 words) - 22:33, 4 September 2024
  • Thumbnail for Lincosamides
    to macrolide treatment have been isolated and found to possess mutations at the transferase binding pocket in the 23S ribosomal subunit. Macrolide-resistant...
    20 KB (2,133 words) - 12:14, 20 November 2023
  • Thumbnail for Whooping cough
    clarithromycin, or azithromycin are typically the recommended treatment. Newer macrolides are frequently recommended due to lower rates of side effects....
    50 KB (4,848 words) - 04:11, 7 November 2024
  • Thumbnail for Asthma
    minimal relief provided for asthma symptoms. Macrolide antibiotics, particularly the azalide macrolide azithromycin, are a recently added Global Initiative...
    167 KB (18,029 words) - 17:59, 27 October 2024
  • Thumbnail for Cardiac arrest
    such as certain anti-arrhythmics, anti-depressants, and quinolone or macrolide antibiotics. Another condition that promotes arrhythmias is Wolff-Parkinson-White...
    125 KB (13,739 words) - 04:56, 2 November 2024
  • Thumbnail for Tonsillitis
    recommended. In those who are allergic to penicillin, cephalosporins or macrolides may be used. In children with frequent episodes of tonsillitis, tonsillectomy...
    33 KB (3,336 words) - 13:13, 2 August 2024
  • Thumbnail for Tacrolimus
    Tacrolimus (category Macrolides)
    the body's learned (or adaptive) immune response. Chemically, it is a macrolide lactone that was first discovered in 1987, from the fermentation broth...
    43 KB (4,357 words) - 08:39, 29 October 2024
  • Thumbnail for Ivermectin
    Ivermectin (category Macrolides)
    Ivermectin is an antiparasitic drug. After its discovery in 1975, its first uses were in veterinary medicine to prevent and treat heartworm and acariasis...
    79 KB (7,699 words) - 17:51, 9 October 2024
  • Thumbnail for Chlamydia pneumoniae
    lead to asthma. Macrolide antibiotic treatment can improve asthma in a subgroup of patients that remains to be clearly defined. Macrolide benefits were...
    23 KB (2,610 words) - 01:54, 15 October 2024
  • Thumbnail for Klebsiella pneumoniae
    Amino-penicillin Anti-pseudomonal BL−BLI Carbapenems Fluoro-quinolones Macrolide MDR & XDR Meticillin Mono INH Mono RIF Penicillin TMP-SMX Vancomycin Total...
    42 KB (4,195 words) - 03:15, 3 October 2024