• Thumbnail for Malonyl chloride
    Malonyl chloride is the organic compound with the formula CH2(COCl)2. It is the acyl chloride derivative of malonic acid. It is a colorless liquid although...
    2 KB (172 words) - 18:28, 19 August 2022
  • Thumbnail for Oxalyl chloride
    Oxalyl chloride is an organic chemical compound with the formula Cl−C(=O)−C(=O)−Cl. This colorless, sharp-smelling liquid, the diacyl chloride of oxalic...
    10 KB (904 words) - 13:23, 13 July 2024
  • Thumbnail for Malonic acid
    Malonic acid (redirect from Malonyl)
    anhydride, and chloride derivatives. Malonic anhydride can be used as an intermediate to mono-ester or amide derivatives, while malonyl chloride is most useful...
    20 KB (1,953 words) - 20:52, 17 April 2024
  • cyclobutanecarboxylic acid chloride 5006-22-4 C5H7ClO2 chloroacetic acid allyl ester 2916-14-5 C5H7ClO3 ethyl malonyl chloride 36239-09-5 C5H7ClO4 dimethyl...
    20 KB (28 words) - 18:31, 27 December 2023
  • Thumbnail for Zomebazam
    4-amino-1,3-dimethyl-5-methylaminopyrazole (2). Treatment with methyl malonyl chloride (3) gives 4-α-ethoxycarbonylacetylamino-1,3-dimethyl-5-methylaminopyrazole...
    3 KB (147 words) - 22:52, 6 March 2024
  • C4H5ClO cyclopropanecarboxylic acid chloride 4023-34-1 C4H5ClO methacryloyl chloride 920-46-7 C4H5ClO3 methyl malonyl chloride 37517-81-0 C4H5F5O ethyl pentafluoroethyl...
    22 KB (34 words) - 23:53, 21 April 2022
  • Thumbnail for Olivetol
    synthase (PKS)-type reaction from hexanoyl-CoA and three molecules of malonyl-CoA by an aldol condensation of a tetraketide intermediate. In 2009, Taura...
    9 KB (748 words) - 14:27, 24 March 2024
  • Thumbnail for Humulone
    of humulone in Humulus lupulus starts with an isovaleryl-CoA unit and 3 malonyl-CoA units catalyzed by phlorovalerophenone synthase. This conversion yields...
    7 KB (670 words) - 19:15, 12 February 2024
  • Thumbnail for Acridine
    reaction 3 malonyl-CoA + N-methylanthraniloyl-CoA ⇌ 4 CoA + 1,3-dihydroxy-N-methylacridone + 3 CO2 Thus, the two substrates of this enzyme are malonyl-CoA and...
    15 KB (1,349 words) - 11:38, 24 January 2024
  • Thumbnail for Curcumin
    5 malonyl-CoA molecules that eventually arylize into a curcuminoid. The second mechanism involves two cinnamate units coupled together by malonyl-CoA...
    27 KB (2,425 words) - 09:25, 2 May 2024
  • Thumbnail for Acetyl-CoA
    synthesize fatty acids through carboxylation by acetyl-CoA carboxylase into malonyl CoA, the first committed step in the synthesis of fatty acids. This conversion...
    22 KB (2,106 words) - 13:45, 19 July 2024
  • Thumbnail for Thioester
    of fatty acids and mevalonate, precursor to steroids. Examples include malonyl-CoA, acetoacetyl-CoA, propionyl-CoA, cinnamoyl-CoA, and acyl carrier protein...
    13 KB (1,388 words) - 12:26, 19 July 2024
  • Thumbnail for Apigenin
    synthase (CHS) uses consecutive condensations of three equivalents of malonyl CoA followed by aromatization to convert p-coumaroyl-CoA to chalcone. Chalcone...
    11 KB (967 words) - 16:32, 27 May 2024
  • Thumbnail for Glibenclamide
    Unger RH, Foster DW, McGarry JD (July 1994). "More direct evidence for a malonyl-CoA-carnitine palmitoyltransferase I interaction as a key event in pancreatic...
    15 KB (1,138 words) - 15:45, 7 June 2024
  • Thumbnail for Cannabigerol
    synthase assembly protein and subsequent condensation with three molecules of malonyl-CoA. This polyketide is cyclized to olivetolic acid via olivetolic acid...
    11 KB (985 words) - 16:21, 25 June 2024
  • Thumbnail for Coniine
    derived from two malonyl and a butyryl CoA, which are derived in the usual way from acetyl-CoA. Further elongation of butyryl-CoA using 2 malonyl-CoA forms 5-ketooctanal...
    29 KB (3,358 words) - 16:48, 23 June 2024
  • Thumbnail for Hyperforin
    condensation of one molecule of isobutyryl-CoA and three molecules of malonyl-CoA, both catalyzed by Isobutyrophenone synthase. Type III PKS enzymes...
    18 KB (1,728 words) - 03:49, 23 September 2023
  • Thumbnail for Phloroglucinol
    polyketide synthase. The synthesis begins with the condensation of three malonyl-CoAs. Then decarboxylation followed by the cyclization of the activated...
    20 KB (1,959 words) - 13:12, 7 February 2024
  • enflurane 13838-16-9 C3H2ClNO2 chloroacetyl isocyanate 4461-30-7 C3H2Cl2O2 malonyl dichloride 1663-67-8 C3H2F5NO pentafluoropropionamide 354-76-7 C3H2N2 malononitrile...
    17 KB (28 words) - 15:50, 20 March 2022
  • Thumbnail for Daptomycin
    are an acyltransferase (AT) and a ketosynthase (KS). The AT acts upon a malonyl-CoA substrate and transfers an acyl group to the thiol of the ACP domain...
    38 KB (3,770 words) - 05:43, 1 July 2024
  • Thumbnail for Cyanidin
    group. The compound reacts with naringenin-chalcone synthase and three malonyl CoA molecules to add six carbon atoms and three more keto groups ring through...
    9 KB (817 words) - 10:13, 9 April 2024
  • Thumbnail for Lipid
    molecules synthesized by chain-elongation of an acetyl-CoA primer with malonyl-CoA or methylmalonyl-CoA groups in a process called fatty acid synthesis...
    71 KB (7,373 words) - 05:37, 2 July 2024
  • Thumbnail for Hexobarbital
    is referred to by Hercule Poirot as both N-methyl-cyclo-hexenyl-methyl-malonyl urea and Evipan. Lexikon der Neurowissenschaft: Hexobarbital (in German)...
    24 KB (2,273 words) - 13:47, 8 March 2024
  • acid is subjected to ω-oxidation and then tob-oxidation, this generates malonyl-CoA which is further used in saturated fatty acid synthesis. The determination...
    35 KB (3,136 words) - 21:41, 23 June 2024
  • the Acyl Carrier Protein (ACP) by a KS domain, followed by transfer to malonyl-ACP via decarboxylative Claisen condensation. This fragment is then able...
    33 KB (3,142 words) - 17:38, 21 February 2024
  • Thumbnail for Naringenin
    hydrolytic action of the liver enzyme naringinase. Naringenin is derived from malonyl-CoA and 4-coumaroyl-CoA. The latter is derived from phenylalanine. The...
    13 KB (1,229 words) - 04:36, 10 May 2024
  • Thumbnail for Prodigiosin
    protein (ACP) by a keto-synthase (KS) domain, followed by transfer to malonyl-ACP via decarboxylative Claisen condensation catalysed by the enzyme pigJ...
    14 KB (1,405 words) - 14:27, 24 March 2024
  • Thumbnail for Active site
    broken down when strychnine is added. It inhibits glycine receptors(a chloride channel) and a much lower level of neurotransmitter concentration can trigger...
    41 KB (4,859 words) - 20:41, 22 July 2024
  • Thumbnail for Leptospermone
    grandiflorone). Phloroglucinol is biosynthesized in a single step from malonyl-CoA and could be the intermediate, but other routes of biosynthesis may...
    6 KB (631 words) - 22:05, 21 January 2022
  • Thumbnail for Yangonin
    glutathione levels. Yangonin is biosynthesized from coumaroyl-CoA and malonyl-CoA. Malani, Joji (2002-12-03). "Evaluation of the effects of Kava on the...
    4 KB (295 words) - 03:54, 27 December 2022