• Thumbnail for Mitochondrial apoptosis-induced channel
    mitochondrial apoptosis-induced channel (or MAC), is an early marker of the onset of apoptosis. This ion channel is formed on the outer mitochondrial...
    5 KB (498 words) - 23:13, 3 January 2024
  • Thumbnail for Bcl-2 family
    consists of members that either promote or inhibit apoptosis, and control apoptosis by governing mitochondrial outer membrane permeabilization (MOMP), which...
    16 KB (2,160 words) - 15:15, 1 October 2024
  • Thumbnail for Apoptosis-inducing factor
    Apoptosis inducing factor is involved in initiating a caspase-independent pathway of apoptosis (positive intrinsic regulator of apoptosis) by causing...
    9 KB (1,121 words) - 00:24, 2 December 2023
  • Thumbnail for Apoptosis regulator BAX
    Apoptosis Apoptosome Bcl-2 BH3 interacting domain death agonist (BID) Caspases Cytochrome c Noxa Mitochondrion p53 upregulated modulator of apoptosis...
    18 KB (2,092 words) - 06:47, 29 September 2024
  • Thumbnail for Mitochondrion
    et al. (2006). "Mitochondrial calcium signalling and cell death: approaches for assessing the role of mitochondrial Ca2+ uptake in apoptosis". Cell Calcium...
    167 KB (18,361 words) - 14:53, 3 November 2024
  • Thumbnail for Apoptosis
    Apoptosis (from Ancient Greek: ἀπόπτωσις, romanized: apóptōsis, lit. 'falling off') is a form of programmed cell death that occurs in multicellular organisms...
    91 KB (10,639 words) - 09:36, 29 October 2024
  • permeability transition (mPT or MPT), can lead to mitochondrial swelling and cell death through apoptosis or necrosis depending on the particular biological...
    32 KB (3,440 words) - 20:29, 23 March 2024
  • measure used to compare the strengths of anesthetic vapors Mitochondrial apoptosis-induced channel, the cytochrome c release pore of apoptotic mitochondria...
    10 KB (1,229 words) - 23:23, 3 November 2024
  • Thumbnail for Excitotoxicity
    Nicotera P (October 1995). "Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function". Neuron. 15 (4): 961–973...
    25 KB (2,792 words) - 21:57, 3 September 2024
  • channels may also trigger apoptosis through insertion in mitochondrial membranes. Aβ injection in rats has been shown to damage mitochondrial structure...
    22 KB (2,645 words) - 22:46, 16 July 2024
  • Thumbnail for Ceramide
    Ceramide (section Apoptosis)
    mitochondria in inducing apoptosis. However, owing to the conflicting and variable nature of studies into the role of ceramide in apoptosis, the mechanism...
    30 KB (3,360 words) - 02:17, 7 November 2024
  • Thumbnail for Phospholipid scramblase
    mitochondria during apoptosis. hPLSCR1 and its mitochondrial counterpart hPLSCR3 are phosphorylated by PKCδ during PKC-δ-induced apoptosis. While the consequence...
    16 KB (1,688 words) - 00:01, 8 June 2024
  • Thumbnail for Bcl-2-like protein 1
    Mcl-1 by caspase-3 in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Jurkat leukemia T cells". The Journal of Biological...
    19 KB (2,223 words) - 05:29, 3 January 2024
  • Thumbnail for TP53-inducible glycolysis and apoptosis regulator
    also protects glioma cells against hypoxia-induced apoptosis by decreasing ROS (conferring evasion of apoptosis). TIGAR is also overexpressed in some breast...
    28 KB (3,453 words) - 14:43, 21 June 2024
  • Thumbnail for Translocator protein
    have been shown to induce apoptosis in human colorectal cancer cells.[citation needed] In lymphatic tissues, TSPO modulates apoptosis of thymocytes via...
    28 KB (3,182 words) - 10:30, 15 July 2024
  • A, O'Rourke B, Marbán E (June 2001). "Mitochondrial ATP-sensitive potassium channels inhibit apoptosis induced by oxidative stress in cardiac cells"....
    24 KB (2,579 words) - 19:20, 2 October 2024
  • Thumbnail for Bcl-2 homologous antagonist killer
    and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a...
    21 KB (2,597 words) - 09:19, 7 July 2024
  • Thumbnail for Neurotoxin
    remodeling appears to be mediated through ammonia-induced mitochondrial permeability transition. This mitochondrial transition is a direct result of glutamine...
    89 KB (9,714 words) - 15:22, 18 September 2024
  • Thumbnail for Cytochrome c
    Andreau K, Roumier T, Piacentini M, Kroemer G (December 2003). "Mitochondrial apoptosis induced by the HIV-1 envelope". Annals of the New York Academy of Sciences...
    33 KB (3,819 words) - 07:18, 8 October 2024
  • Thumbnail for VDAC1
    VDAC1 (category Ion channels)
    cell metabolism, mitochondrial apoptosis, and spermatogenesis. Over expression and misregulation of this pore could lead to apoptosis in the cell leading...
    34 KB (4,087 words) - 22:19, 16 July 2024
  • Thumbnail for Mitochondria associated membranes
    mitochondria and in regulation of calcium homeostasis, mitochondrial function, autophagy and apoptosis. They also play a role in development of neurodegenerative...
    12 KB (1,416 words) - 15:35, 24 October 2024
  • Thumbnail for VDAC2
    VDAC2 (category Ion channels)
    VDACs are generally involved in the regulation of cell metabolism, mitochondrial apoptosis, and spermatogenesis. Additionally, VDAC2 participates in cardiac...
    21 KB (2,675 words) - 23:22, 16 July 2024
  • Thumbnail for Medical use of arsenic trioxide
    forms, which activates further processes leading to apoptosis. Regardless of whether apoptosis is induced externally or internally, it always involves caspases...
    64 KB (6,684 words) - 21:05, 6 November 2024
  • Thumbnail for Bcl-2
    Bcl-2 (category Apoptosis)
    programmed cell death (apoptosis) while other BCL2 family members can either inhibit or induce it. It was the first apoptosis regulator identified in...
    41 KB (4,564 words) - 10:38, 29 September 2024
  • Thumbnail for Rottlerin
    Rottlerin (category Potassium channel openers)
    there is a decrease in apoptosis compared to no stimulation of BKCa++ channels. Rottlerin also enhances the cardioplegia-induced phosphorylation of Akt...
    17 KB (1,665 words) - 23:42, 20 September 2023
  • Thumbnail for SOD2
    this term was replaced by apoptosis to emphasize its role opposite mitosis in tissue kinetics. In later stages of apoptosis the entire cell becomes fragmented...
    26 KB (3,223 words) - 21:03, 2 December 2023
  • translational elongation factor mitochondrial AARS NM_001605 alanyl-tRNA synthetase AARS2 NM_020745 alanyl-tRNA synthetase 2, mitochondrial AARSD1 NM_001261434 alanyl-tRNA...
    48 KB (4,612 words) - 23:41, 12 December 2023
  • Pseudoapoptosis (category Apoptosis)
    when describing an accelerated, drug induced apoptotic pathway by bleomycin. Cell death occurs as it would in apoptosis, but certain apoptotic mechanisms...
    7 KB (845 words) - 00:58, 24 April 2018
  • Thumbnail for Parkin (protein)
    suppressing both mitochondria-dependent and -independent apoptosis. Mutations are associated with mitochondrial dysfunction, leading to neuronal death in Parkinson's...
    47 KB (5,731 words) - 11:29, 22 June 2024
  • Thumbnail for Brain mitochondrial carrier protein 1
    increasing ATP synthesis, mitochondrial polarization, and the prevention of apoptosis. It also maintains the potential of the mitochondrial membrane and lessens...
    13 KB (1,733 words) - 16:04, 23 March 2024