• Thumbnail for Morphine-3-glucuronide
    Morphine-3-glucuronide is a metabolite of morphine produced by UGT2B7. It is not active as an opioid agonist, but does have some action as a convulsant...
    4 KB (296 words) - 00:38, 5 May 2023
  • Thumbnail for Morphine-6-glucuronide
    Morphine-6-glucuronide (M6G) is a major active metabolite of morphine. M6G is formed from morphine by the enzyme UGT2B7. It has analgesic effects more...
    7 KB (567 words) - 17:41, 9 January 2024
  • Thumbnail for Buprenorphine-3-glucuronide
    norbuprenorphine-3-glucuronide), B3G is not a substrate for P-glycoprotein, and hence may cross the blood-brain-barrier significantly. Morphine-3-glucuronide Brown...
    4 KB (238 words) - 16:53, 28 April 2024
  • Thumbnail for Norbuprenorphine-3-glucuronide
    amounts. Morphine-3-glucuronide Brown SM, Holtzman M, Kim T, Kharasch ED (December 2011). "Buprenorphine metabolites, buprenorphine-3-glucuronide and...
    4 KB (228 words) - 16:13, 2 October 2024
  • Thumbnail for Morphine
    24-hour extended-release dosage. Morphine and its major metabolites, morphine-3-glucuronide and morphine-6-glucuronide, can be detected in blood, plasma...
    141 KB (13,802 words) - 17:11, 30 September 2024
  • Thumbnail for Glucuronide
    bond of a glucuronide are called glucuronidases. Miquelianin (Quercetin 3-O-glucuronide) Morphine-6-glucuronide Scutellarein-7-glucuronide The American...
    2 KB (173 words) - 21:50, 31 December 2020
  • Thumbnail for Heroin
    Heroin (redirect from Diacetyl morphine)
    activated by the morphine metabolite morphine-6β-glucuronide but not morphine itself. The third subtype of third opioid type is the mu-3 receptor, which...
    116 KB (11,944 words) - 23:10, 26 September 2024
  • Thumbnail for 6-Monoacetylmorphine
    M3G, morphine-3-glucuronide an inactive metabolite of morphine much as 3-MAM is the less active metabolite of heroin (notably here as morphine is an...
    8 KB (735 words) - 18:27, 24 June 2024
  • Thumbnail for Opiate
    Opiate (section Morphine)
    also derived from morphine. Morphine is metabolized in the liver to morphine-3-glucuronide (M3G) and morphine-6-glucuronide (M6G), and are excreted by...
    31 KB (3,724 words) - 19:07, 2 July 2024
  • Thumbnail for Toll-like receptor
    Sakurada T (2009). Mechanism of allodynia evoked by intrathecal morphine-3-glucuronide in mice. International Review of Neurobiology. Vol. 85. pp. 207–19...
    61 KB (6,771 words) - 07:38, 8 October 2024
  • Thumbnail for Hydromorphone
    to hydromorphone-3-glucuronide, which has no analgesic effects. As similarly seen with the morphine metabolite, morphine-3-glucuronide, a build-up in levels...
    44 KB (4,084 words) - 14:12, 18 October 2024
  • Thumbnail for Morphine-N-oxide
    Schedule I controlled substance in the US. Codeine-N-oxide Morphine-6-glucuronide Morphine-3-glucuronide Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias...
    4 KB (278 words) - 16:47, 11 January 2024
  • Thumbnail for Furosemide
    and Toxicology. 25 (3): 123–128. PMID 3557737. Brater DC (1991). "Clinical pharmacology of loop diuretics". Drugs. 41 (Supplement 3): 14–22. doi:10...
    37 KB (3,619 words) - 01:04, 1 September 2024
  • Thumbnail for Muscimol
    step reaction. 3-bromo-5-aminomethyl-isoxazole (1) was refluxed in a mixture of methanol and potassium hydroxide for 30 hours, resulting in 3...
    37 KB (3,825 words) - 21:25, 7 October 2024
  • Thumbnail for Glutamine
    subjects who received a placebo (median 3 vs. median 4), fewer hospitalizations for sickle cell pain (median 2 vs. median 3), and fewer days in the hospital...
    28 KB (2,559 words) - 01:39, 9 September 2024
  • Thumbnail for Baclofen
    placebo-controlled clinical trial [ISRCTN32121581]". BMC Psychiatry. 3: 16. doi:10.1186/1471-244X-3-16. PMC 293465. PMID 14624703. Allen Jr LV (17 November 2010)...
    34 KB (3,276 words) - 18:27, 30 September 2024
  • Thumbnail for Ciprofloxacin
    Ciprofloxacin (category 1,4-di-hydro-7-(1-piperazinyl)-4-oxo-3-quinolinecarboxylic acids)
    bronchitis". The Journal of Antimicrobial Chemotherapy. 18 (3): 407–413. doi:10.1093/jac/18.3.407. PMID 3490468. Vardakas KZ, Siempos II, Grammatikos A...
    66 KB (6,680 words) - 22:22, 15 August 2024
  • Thumbnail for Clarithromycin
    most common side effects are gastrointestinal: diarrhea (3%), nausea (3%), abdominal pain (3%), and vomiting (6%). It also can cause headaches, insomnia...
    29 KB (2,711 words) - 12:25, 26 September 2024
  • Thumbnail for Forensic chemistry
    "Interpretation of the Presence of 6-monoacetylmorphine in the Absence of Morphine-3-glucuronide in Urine Samples: Evidence of Heroin Abuse". Therapeutic Drug Monitoring...
    43 KB (4,484 words) - 10:33, 21 August 2024
  • Thumbnail for Lemon balm
    Asia, but now naturalised elsewhere. It grows to a maximum height of 1 m (3 ft 3 in). The leaves have a mild lemon scent. During summer, small white flowers...
    17 KB (1,695 words) - 10:49, 20 August 2024
  • Thumbnail for GABA
    GABA (redirect from 3-Carboxypropylamine)
    central nervous system development". Neurosci Bull. 24 (3): 195–200. doi:10.1007/s12264-008-0109-3. PMC 5552538. PMID 18500393. Ben-Ari Y, Gaiarsa JL, Tyzio...
    53 KB (5,776 words) - 11:10, 19 October 2024
  • Thumbnail for GABA analogue
    acid/3-methylbutanoic acid) – constituent of valerian; has anticonvulsant effects; PAM of the GABAA receptor Derivatives: isovalerate (isopentanoate/3-methylbutanoate)...
    8 KB (754 words) - 04:40, 27 January 2024
  • Thumbnail for Phenibut
    dose in healthy volunteers, its elimination half-life was approximately 5.3 hours and the drug was largely (63%) excreted in the urine unchanged. Some...
    36 KB (2,964 words) - 16:40, 10 October 2024
  • Thumbnail for Fipronil
    6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl)pyrazole-3-carbonitrile) is a white, solid powder with a moldy odor. It is degraded slightly...
    33 KB (3,184 words) - 14:34, 8 June 2024
  • Thumbnail for 1,4-Butanediol
    Encyclopedia of Industrial Chemistry, doi:10.1002/14356007.a13_487, ISBN 3-527-30673-0 "1,4-Butanediol Production And Uses", 30 July 2023, retrieved...
    18 KB (1,828 words) - 10:39, 19 October 2024
  • Thumbnail for Β-Carboline
    Β-Carboline (redirect from 244-63-3)
    position 3 reduce the effect of benzodiazepine on GABA-A receptors and can therefore have convulsive, anxiogenic and memory enhancing effects. Moreover, 3...
    27 KB (2,634 words) - 01:33, 12 October 2024
  • Thumbnail for Toll-like receptor 4
    Sakurada T (2009). Mechanism of allodynia evoked by intrathecal morphine-3-glucuronide in mice. International Review of Neurobiology. Vol. 85. pp. 207–19...
    75 KB (9,082 words) - 22:17, 25 September 2024
  • Thumbnail for GABA receptor agonist
    cells and rodent central neurones". British Journal of Pharmacology. 104 (3): 619–628. doi:10.1111/j.1476-5381.1991.tb12479.x. PMC 1908220. PMID 1665745...
    8 KB (740 words) - 14:44, 20 August 2024
  • Thumbnail for Flumazenil
    is 200 μg every 1–2 minutes until the effect is seen, up to a maximum of 3 mg per hour. It is available as a clear, colourless solution for intravenous...
    23 KB (2,420 words) - 20:16, 30 September 2024
  • Thumbnail for Γ-Hydroxybutyric acid
    May 2012. Weil A, Winifred R (1993). "Depressants". From Chocolate to Morphine (2nd ed.). Boston/New York: Houghton Mifflin Company. p. 77. ISBN 978-0-395-66079-9...
    89 KB (9,448 words) - 10:19, 5 October 2024