NF-kappa-B-activating protein is a protein that in humans is encoded by the NKAP gene. GRCh38: Ensembl release 89: ENSG00000101882 – Ensembl, May 2017...
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Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a family of transcription factor protein complexes that controls transcription...
89 KB (9,773 words) - 11:16, 4 October 2024
IKBKG (redirect from Inhibitor of kappa light polypeptide gene enhancer in B-cells)
NF-kappa-B essential modulator (NEMO) also known as inhibitor of nuclear factor kappa-B kinase subunit gamma (IKK-γ) is a protein that in humans is encoded...
26 KB (3,277 words) - 15:04, 23 July 2024
TMEM101 (section Activation of NF-κB Signaling Pathway)
to breast cancer. Known aliases of TMEM101 include Putative NF-Kappa-B-Activating Protein 130, FLJ23987, and MGC4251. TMEM101 is located on the minus...
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The IκB kinase enzyme complex is part of the upstream NF-κB signal transduction cascade. The IκBα (inhibitor of nuclear factor kappa B) protein inactivates...
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NKAPD1 (category Human proteins)
NKAPD1 (NF-kappa-B-activating protein domain containing 1) is a protein, which in humans, is encoded by the gene NKAPD1. This protein is also commonly...
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IκBα (redirect from I-kappa B protein)
function to inhibit the NF-κB transcription factor. IκBα inhibits NF-κB by masking the nuclear localization signals (NLS) of NF-κB proteins and keeping them...
13 KB (1,526 words) - 18:27, 5 February 2024
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B and CD257 among other names, is a protein that in humans...
25 KB (3,095 words) - 14:05, 12 March 2024
Transforming growth factor beta (redirect from Transforming growth factor-b)
1996). "TGF beta 1 inhibits NF-kappa B/Rel activity inducing apoptosis of B cells: transcriptional activation of I kappa B alpha". Immunity. 5 (1): 31–40...
67 KB (8,184 words) - 20:48, 31 October 2024
PMID 24886973. Hou, Shihe (November 14, 2003). "Phosphorylation of serine 337 of NF-kappaB p50 is critical for DNA binding". The Journal of Biological Chemistry...
67 KB (7,955 words) - 20:50, 29 July 2024
NF-kappa-B p65 subunit is a protein that in humans is encoded by the RELA gene. RELA, also known as p65, is a REL-associated protein involved in NF-κB...
56 KB (6,507 words) - 07:54, 19 July 2024
Nuclear factor NF-kappa-B p105 subunit is a protein that in humans is encoded by the NFKB1 gene. This gene encodes a 105 kD protein which can undergo cotranslational...
20 KB (2,363 words) - 03:00, 19 December 2023
AKT1 (category Protein kinases)
Schraven B, Baier G (Aug 2001). "Complex formation and cooperation of protein kinase C theta and Akt1/protein kinase B alpha in the NF-kappa B transactivation...
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with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase...
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deactivate the p53 protein, and may have a role in activating T helper 17 cells. Lamin A is a protein that had been identified as a direct activator of Sirtuin...
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inhibitor of NF-κB, allowing NF-κB to be activating. When MC160 binds heat shock protein 90, IKK is degraded and the inhibitor remains bound to NF-κB, thus making...
21 KB (2,676 words) - 10:59, 6 January 2024
Tumor necrosis factor (section Protein)
wasting by activating the NF-κB pathway, which activates the ubiquitin–proteasome pathway to degrade protein, and by inhibiting the activation of satellite...
49 KB (6,233 words) - 07:30, 6 November 2024
BCL10 (category Proteins)
(1999). "CIPER, a novel NF kappaB-activating protein containing a caspase recruitment domain with homology to Herpesvirus-2 protein E10". J. Biol. Chem....
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characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3". Cell. 122 (5): 669–682. doi:10.1016/j.cell.2005...
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RANKL (redirect from Receptor activator of nuclear factor kappa-B ligand)
osteoblasts' surface-bound RANKL activating the osteoclasts' surface-bound receptor activator of nuclear factor kappa-B (RANK). Recent studies suggest that...
28 KB (3,305 words) - 13:29, 8 November 2024
AP-1 transcription factor (redirect from Activation Protein 1)
2003). "Activation of mitogen-activated protein kinase and NF-kappaB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane protein". Journal...
41 KB (4,468 words) - 17:08, 21 September 2024
TNFAIP3 (redirect from Alpha-induced protein 3)
(TNF). The protein encoded by this gene is a zinc finger protein and a deubiquitinating enzyme, and has been shown to inhibit NF-kappa B activation as well...
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Kovalenko AV, Wallach D (February 1997). "MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1". Nature. 385 (6616): 540–544. doi:10...
22 KB (2,808 words) - 16:03, 28 October 2024
superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members,...
18 KB (1,937 words) - 21:50, 5 January 2024
MYD88 (category Human proteins)
interleukin-1beta -induced NF-kappa B activation by calcium/calmodulin-dependent protein kinase kinase occurs through Akt activation associated with interleukin-1...
20 KB (2,250 words) - 15:55, 30 July 2024
Nuclear factor NF-kappa-B p100 subunit is a protein that in humans is encoded by the NFKB2 gene. NF-κB has been detected in numerous cell types that express...
10 KB (1,276 words) - 00:06, 3 December 2023
Cheong J, Meltzer PS, Lee YC, Lee JW (June 2000). "Activating protein-1, nuclear factor-kappaB, and serum response factor as novel target molecules...
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calcineurin activation. Akt and calcineurin are both activators of NF-kappa-B (p65). Through their activation, PGC-1α seems to activate NF-kappa-B. Increased...
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Transcription factor (redirect from Transcription factor protein)
region) 4.1.1 Family: Rel/ankyrin; NF-kappaB 4.1.2 Family: ankyrin only 4.1.3 Family: NFAT (Nuclear Factor of Activated T-cells) (NFATC1, NFATC2, NFATC3)...
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kappa B proteins. This protein functions as a transcriptional coactivator that activates through its association with NF-kappa B homodimers. The expression...
23 KB (2,553 words) - 23:08, 3 August 2024