• Thumbnail for NOVA1
    RNA-binding protein Nova-1 is a protein that in humans is encoded by the NOVA1 gene. This gene encodes a neuron-specific RNA-binding protein, a member...
    7 KB (843 words) - 06:05, 3 January 2024
  • Thumbnail for Evolution of the brain
    created with stem cells into which they reintroduced the archaic gene variant NOVA1 present in Neanderthals and Denisovans via CRISPR-Cas9 shows that it has...
    71 KB (8,143 words) - 03:39, 18 November 2024
  • Thumbnail for KH domain
    revealed a beta-alpha-alpha-beta-beta-alpha structure. Autoantibodies to NOVA1, a KH domain protein, cause paraneoplastic opsoclonus ataxia. The KH domain...
    7 KB (650 words) - 16:40, 9 September 2024
  • Thumbnail for CRISPR gene editing
    Madrigal AA, et al. (February 2021). "Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment". Science. 371 (6530). doi:10...
    170 KB (19,890 words) - 19:36, 10 November 2024
  • Q99466 10695 NOTO HGNC:31839 A8MTQ0 10696 NOTUM HGNC:27106 Q6P988 10697 NOVA1 HGNC:7886 P51513 10698 NOVA2 HGNC:7887 Q9UNW9 10699 NOX1 HGNC:7889 Q9Y5S8...
    282 KB (17 words) - 08:00, 19 November 2024
  • than in anatomically-modern humans. When the neanderthal version of the NOVA1 gene is inserted into stem cells it creates neurons with fewer synapses...
    53 KB (6,157 words) - 05:54, 2 November 2024
  • interactions between the neuron-specific RNA-binding protein and splicing factors NOVA1 and NOVA2 in the mouse brain, identifying RNA binding sites that contained...
    50 KB (4,888 words) - 11:50, 22 February 2024
  • interaction maps for the neuron-specific RNA-binding protein and splicing factor NOVA1 and NOVA2; since then a number of other splicing factor maps have been generated...
    10 KB (1,160 words) - 12:13, 2 October 2024
  • created with stem cells into which they reintroduced the archaic gene variant NOVA1 present in Neanderthals and Denisovans via CRISPR-Cas9 shows that it has...
    139 KB (13,101 words) - 00:50, 25 September 2024
  • neuronal RBPs NOVA1/2 are translocated from the nucleus to the cytoplasm during pilocarpine-induced seizure in mice, and it was found that NOVA1/2 regulates...
    47 KB (4,698 words) - 21:10, 11 November 2024
  • binding proteins such as neuronal specific RNA-binding proteins, namely NOVA1, control the alternative splicing of a subset of hnRNA by recognizing and...
    39 KB (4,540 words) - 15:46, 4 November 2024
  • Thumbnail for HNRNPK
    IGF2BP3; KHDRBS1; KHDRBS2; KHDRBS3; KHSRP; KRR1; MEX3A; MEX3B; MEX3C; MEX3D; NOVA1; NOVA2; PCBP1; PCBP2; PCBP3; PCBP4; PNO1; PNPT1; QKI; SF1; TDRKH; GRCh38:...
    17 KB (2,012 words) - 15:40, 22 December 2023
  • Ibrahim EC (August 2016). "MicroRNA screening identifies a link between NOVA1 expression and a low level of IKAP in familial dysautonomia". Disease Models...
    21 KB (2,325 words) - 09:01, 28 October 2024