Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that exists in all eukaryotes. Its main function is to reduce errors in gene expression by...

lower species, such as yeast—employ a nonsense-mediated mRNA decay pathway, which degrades mRNAs containing nonsense mutations before they are able to be...

recognition in translation, termination of translation, and nonsense mediated mRNA decay via the SURF complex. All cells need to make proteins through...

nonsense-mediated mRNA decay pathway (NMD); the nonstop mediated mRNA decay pathways (NSD); and the no-go mediated mRNA decay pathway (NGD). Nonsense-mediated...

in general mRNA decay, nonsense-mediated mRNA decay, adenylate-uridylate-rich element mediated mRNA decay, and microRNA (miRNA) induced mRNA silencing...

spliced beta-globin mRNAs: a single point mutation generates transcripts sensitive and insensitive to nonsense-mediated mRNA decay". Blood. 99 (5): 1811–1816...

play a major role in mRNA surveillance. More specifically, they are found in the nonsense mediated decay pathway (NMD), wherein mRNA transcripts with premature...

alternative pre-mRNA splicing, mRNA export, genome stabilization, nonsense-mediated decay, and translation. SR proteins alternatively splice pre-mRNA by preferentially...

(PEs); also called premature termination codon (PTC) exons or nonsense-mediated decay (NMD) exons] are a class of cassette exons that contain PTCs. Inclusion...

spliced beta-globin mRNAs: a single point mutation generates transcripts sensitive and insensitive to nonsense-mediated mRNA decay". Blood. 99 (5): 1811–6...

initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature...

In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is...

single-stranded DNA in telomere maintenance and single-stranded RNA in nonsense-mediated mRNA decay (NMD). The SMG6 gene also contains one of 27 SNPs associated...

nonsense-mediated mRNA decay (NMD). PABPC1 binds to the poly(A) tail and interact with eIF4G, which stabilizes the circularization of mRNAs. This structure...

cytosol composed of proteins and RNA that assemble into 0.1–2 μm membraneless organelles when the cell is under stress. The mRNA molecules found in stress granules...

mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream...

Lykke-Andersen, Søren; Jensen, Torben Heick (2015-09-23). "Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes". Nature Reviews...

mRNA quality control than it does in actual protein synthesis. One of the ways that it does this quality control is through nonsense-mediated decay....

mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream...

family. This gene encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity...

focused on mRNA decay and the molecular basis of human disease. Her research Specifically, she was the first to describe nonsense-mediated mRNA decay, work...

this problem through the promotion of mRNA degradation or by changing pre-mRNA splicing, nonsense-mediated mRNA decay, or translation, thus increasing CFTR...

the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay". Genes & Development. 20 (3): 355–67. doi:10.1101/gad.1389006...

(2004). "An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay". Nature. 427 (6976): 753–7. Bibcode:2004Natur.427...

in proteins involved in nonsense mediated mRNA decay, in proteins such as SMG5 and SMG6, and in processing of 18S ribosomal RNA. The majority of PIN-domain...

export of mature mRNA from the nucleus. An increase in cellular ASF/SF2 also will increase the efficiency of nonsense-mediated mRNA decay (NMD), favoring...

nonsense mediated mRNA decay factor (C. elegans)". Yang L, Kraft VA, Pfeiffer S, Merl-Pham J, Bao X, An Y, et al. (June 2020). "Nonsense-mediated decay...

PMID 12699629. S2CID 6685276. "Entrez Gene: SMG5 Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)". Glavan F, Behm-Ansmant I, Izaurralde E...

Reimer R, Hohenberg H, Schwartz K, Vernet M, Eschenhagen T, Carrier L (Jul 2009). "Nonsense-mediated mRNA decay and ubiquitin-proteasome system regulate...

SMCP: Sperm mitochondrial-associated cysteine-rich protein SMG7: nonsense mediated mRNA decay factor SMYD3 (1q44) SPG23 SPRR1A: Cornifin-A SPRR1B: Cornifin-B...