A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses...
46 KB (5,492 words) - 03:05, 21 June 2024
p38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines...
14 KB (1,385 words) - 10:32, 28 April 2024
Mitogen-activated protein kinase kinase (also known as MAP2K, MEK, MAPKK) is a dual-specificity kinase enzyme which phosphorylates mitogen-activated protein...
3 KB (296 words) - 17:06, 14 September 2023
5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular...
65 KB (7,147 words) - 05:41, 24 June 2024
biology, extracellular signal-regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that...
11 KB (1,128 words) - 19:03, 18 September 2023
Mitogen-activated protein kinase 9 is an enzyme that in humans is encoded by the MAPK9 gene. The protein encoded by this gene is a member of the MAP kinase...
7 KB (792 words) - 02:33, 19 October 2022
its transcriptional activation domain. They belong to the mitogen-activated protein kinase family, and are responsive to stress stimuli, such as cytokines...
14 KB (1,626 words) - 20:50, 30 May 2024
It should not be confused with 5'-AMP-activated protein kinase (AMP-activated protein kinase). Protein kinase A, more precisely known as adenosine 3'...
27 KB (2,665 words) - 17:03, 6 April 2024
ASK1 (redirect from Mitogen-activated protein kinase kinase kinase 5)
of mitogen-activated protein kinase pathway. It activates c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinases in a Raf-independent...
19 KB (2,219 words) - 06:02, 11 March 2024
Mitogen Activated Protein (MAP) kinase kinase kinase (MAPKKK, MKKK, M3K, or, MAP3K) is a serine/threonine-specific protein kinase which acts upon MAP...
11 KB (1,345 words) - 09:11, 2 January 2024
MAPK14 (redirect from Mitogen-activated protein kinase 14)
Mitogen-activated protein kinase 14, also called p38-α, is an enzyme that in humans is encoded by the MAPK14 gene. MAPK14 encodes p38α mitogen-activated...
44 KB (5,265 words) - 05:22, 10 July 2024
important group of protein kinases are the MAP kinases (acronym from: "mitogen-activated protein kinases"). Important subgroups are the kinases of the ERK subfamily...
15 KB (1,619 words) - 21:11, 21 June 2024
MAPK1 (redirect from Mitogen-activated protein kinase 1)
Mitogen-activated protein kinase 1 (MAPK 1), also known as ERK2, is an enzyme that in humans is encoded by the MAPK1 gene. The protein encoded by this...
20 KB (2,283 words) - 00:38, 15 June 2024
PKCs are activated through the same signal transduction pathway as phospholipase C. On the other hand, atypical (a)PKCs (including protein kinase Mζ and...
27 KB (2,716 words) - 18:23, 1 August 2024
P38 or P-38 may refer to: Multisynthetase complex auxiliary component p38 p38 mitogen-activated protein kinases RPP38, ribonuclease P protein subunit...
901 bytes (145 words) - 12:41, 27 January 2024
molecules, including integrin-linked kinase (ILK) and mitogen-activated protein kinase-activated protein kinase-2 (MAPKAPK2) can also serve as PDK2. Phosphorylation...
35 KB (3,831 words) - 00:20, 19 July 2024
MAPKAPK2 (redirect from Mitogen-activated protein kinase-activated protein kinase 2)
peptide N-formyl-met-leu-phe activation of p38 mitogen-activated protein kinase (MAPK) and MAPK-activated protein kinase-2 in human neutrophils". The...
16 KB (1,726 words) - 11:03, 11 April 2024
Philadelphia chromosome (redirect from Bcr-abl fusion protein)
2004). "Chlorogenic acid inhibits Bcr-Abl tyrosine kinase and triggers p38 mitogen-activated protein kinase-dependent apoptosis in chronic myelogenous leukemic...
29 KB (3,538 words) - 15:01, 5 December 2023
cGMP-dependent protein kinase or protein kinase G (PKG) is a serine/threonine-specific protein kinase that is activated by cGMP. It phosphorylates a number...
8 KB (825 words) - 21:37, 20 April 2023
Beta-adrenergic receptor kinase (βARK or βARK1), and is a member of the G protein-coupled receptor kinase subfamily of the Ser/Thr protein kinases that is most highly...
14 KB (1,637 words) - 11:17, 19 June 2022
"Stimulation of glucose transport by AMP-activated protein kinase via activation of p38 mitogen-activated protein kinase". J. Biol. Chem. 276 (44): 41029–34...
10 KB (1,255 words) - 06:02, 24 June 2024
350 of the 500+ human protein kinases are serine/threonine kinases (STK). In enzymology, the term serine/threonine protein kinase describes a class of...
14 KB (1,210 words) - 13:35, 14 June 2024
MAPK8 (redirect from Mitogen-activated protein kinase 8)
Mitogen-activated protein kinase 8 (also known as JNK1) is a ubiquitous enzyme that in humans is encoded by the MAPK8 gene. The protein encoded by this...
16 KB (1,781 words) - 00:37, 15 June 2024
as the mitogen-activated protein kinase (MAPK) cascade. Activation of RAF kinases requires interaction with RAS-GTPases. The three RAF kinase family members...
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gene. The DMPK gene product is a Ser/Thr protein kinase homologous to the MRCK p21-activated kinases and Rho kinase family. Data obtained by using antibodies...
19 KB (2,426 words) - 16:47, 30 March 2024
G protein-coupled receptor kinases (GPCRKs, GRKs) are a family of protein kinases within the AGC (protein kinase A, protein kinase G, protein kinase C)...
18 KB (2,053 words) - 11:08, 8 June 2024
MAP3K1 (category Mitogen-activated protein kinases)
(TGFβR). Mitogen-activated protein kinase kinases (MAP2Ks) are substrates for direct phosphorylation by the MAP3K1 protein kinase. The MAP3K1 kinase domain...
33 KB (3,167 words) - 18:40, 3 December 2023
Trigger a Ribotoxic Stress Response That Activates c-Jun N-terminal Kinase and p38 Mitogen-activated Protein Kinase and Induces Apoptosis". Journal of Biological...
11 KB (1,026 words) - 19:19, 25 April 2024
MAP2K4 (category Mitogen-activated protein kinases)
Dual-specificity mitogen-activated protein kinase kinase 4 is an enzyme that in humans is encoded by the MAP2K4 gene. MAP2K4 encodes a dual-specificity kinase that...
9 KB (1,031 words) - 06:03, 11 March 2024
MAP2K7 (category Mitogen-activated protein kinases)
Dual specificity mitogen-activated protein kinase kinase 7, also known as MAP kinase kinase 7 or MKK7, is an enzyme that in humans is encoded by the MAP2K7...
23 KB (2,694 words) - 17:22, 17 July 2024