• A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses...
    46 KB (5,492 words) - 03:05, 21 June 2024
  • p38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines...
    14 KB (1,385 words) - 10:32, 28 April 2024
  • Mitogen-activated protein kinase kinase (also known as MAP2K, MEK, MAPKK) is a dual-specificity kinase enzyme which phosphorylates mitogen-activated protein...
    3 KB (296 words) - 17:06, 14 September 2023
  • Thumbnail for AMP-activated protein kinase
    5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular...
    65 KB (7,147 words) - 05:41, 24 June 2024
  • biology, extracellular signal-regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that...
    11 KB (1,128 words) - 19:03, 18 September 2023
  • Thumbnail for Mitogen-activated protein kinase 9
    Mitogen-activated protein kinase 9 is an enzyme that in humans is encoded by the MAPK9 gene. The protein encoded by this gene is a member of the MAP kinase...
    7 KB (792 words) - 02:33, 19 October 2022
  • Thumbnail for C-Jun N-terminal kinases
    its transcriptional activation domain. They belong to the mitogen-activated protein kinase family, and are responsive to stress stimuli, such as cytokines...
    14 KB (1,626 words) - 20:50, 30 May 2024
  • Thumbnail for Protein kinase A
    It should not be confused with 5'-AMP-activated protein kinase (AMP-activated protein kinase). Protein kinase A, more precisely known as adenosine 3'...
    27 KB (2,665 words) - 17:03, 6 April 2024
  • Thumbnail for ASK1
    of mitogen-activated protein kinase pathway. It activates c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinases in a Raf-independent...
    19 KB (2,219 words) - 06:02, 11 March 2024
  • Mitogen Activated Protein (MAP) kinase kinase kinase (MAPKKK, MKKK, M3K, or, MAP3K) is a serine/threonine-specific protein kinase which acts upon MAP...
    11 KB (1,345 words) - 09:11, 2 January 2024
  • Thumbnail for MAPK14
    Mitogen-activated protein kinase 14, also called p38-α, is an enzyme that in humans is encoded by the MAPK14 gene. MAPK14 encodes p38α mitogen-activated...
    44 KB (5,265 words) - 05:22, 10 July 2024
  • Thumbnail for Protein kinase
    important group of protein kinases are the MAP kinases (acronym from: "mitogen-activated protein kinases"). Important subgroups are the kinases of the ERK subfamily...
    15 KB (1,619 words) - 21:11, 21 June 2024
  • Thumbnail for MAPK1
    Mitogen-activated protein kinase 1 (MAPK 1), also known as ERK2, is an enzyme that in humans is encoded by the MAPK1 gene. The protein encoded by this...
    20 KB (2,283 words) - 00:38, 15 June 2024
  • PKCs are activated through the same signal transduction pathway as phospholipase C. On the other hand, atypical (a)PKCs (including protein kinase Mζ and...
    27 KB (2,716 words) - 18:23, 1 August 2024
  • P38 or P-38 may refer to: Multisynthetase complex auxiliary component p38 p38 mitogen-activated protein kinases RPP38, ribonuclease P protein subunit...
    901 bytes (145 words) - 12:41, 27 January 2024
  • Thumbnail for Protein kinase B
    molecules, including integrin-linked kinase (ILK) and mitogen-activated protein kinase-activated protein kinase-2 (MAPKAPK2) can also serve as PDK2. Phosphorylation...
    35 KB (3,831 words) - 00:20, 19 July 2024
  • Thumbnail for MAPKAPK2
    peptide N-formyl-met-leu-phe activation of p38 mitogen-activated protein kinase (MAPK) and MAPK-activated protein kinase-2 in human neutrophils". The...
    16 KB (1,726 words) - 11:03, 11 April 2024
  • Thumbnail for Philadelphia chromosome
    2004). "Chlorogenic acid inhibits Bcr-Abl tyrosine kinase and triggers p38 mitogen-activated protein kinase-dependent apoptosis in chronic myelogenous leukemic...
    29 KB (3,538 words) - 15:01, 5 December 2023
  • Thumbnail for CGMP-dependent protein kinase
    cGMP-dependent protein kinase or protein kinase G (PKG) is a serine/threonine-specific protein kinase that is activated by cGMP. It phosphorylates a number...
    8 KB (825 words) - 21:37, 20 April 2023
  • Thumbnail for G protein-coupled receptor kinase 2
    Beta-adrenergic receptor kinase (βARK or βARK1), and is a member of the G protein-coupled receptor kinase subfamily of the Ser/Thr protein kinases that is most highly...
    14 KB (1,637 words) - 11:17, 19 June 2022
  • Thumbnail for Protein kinase, AMP-activated, alpha 1
    "Stimulation of glucose transport by AMP-activated protein kinase via activation of p38 mitogen-activated protein kinase". J. Biol. Chem. 276 (44): 41029–34...
    10 KB (1,255 words) - 06:02, 24 June 2024
  • Thumbnail for Serine/threonine-specific protein kinase
    350 of the 500+ human protein kinases are serine/threonine kinases (STK). In enzymology, the term serine/threonine protein kinase describes a class of...
    14 KB (1,210 words) - 13:35, 14 June 2024
  • Thumbnail for MAPK8
    Mitogen-activated protein kinase 8 (also known as JNK1) is a ubiquitous enzyme that in humans is encoded by the MAPK8 gene. The protein encoded by this...
    16 KB (1,781 words) - 00:37, 15 June 2024
  • Thumbnail for RAF kinase
    as the mitogen-activated protein kinase (MAPK) cascade. Activation of RAF kinases requires interaction with RAS-GTPases. The three RAF kinase family members...
    5 KB (556 words) - 08:06, 3 June 2024
  • Thumbnail for Myotonin-protein kinase
    gene. The DMPK gene product is a Ser/Thr protein kinase homologous to the MRCK p21-activated kinases and Rho kinase family. Data obtained by using antibodies...
    19 KB (2,426 words) - 16:47, 30 March 2024
  • Thumbnail for G protein-coupled receptor kinase
    G protein-coupled receptor kinases (GPCRKs, GRKs) are a family of protein kinases within the AGC (protein kinase A, protein kinase G, protein kinase C)...
    18 KB (2,053 words) - 11:08, 8 June 2024
  • Thumbnail for MAP3K1
    MAP3K1 (category Mitogen-activated protein kinases)
    (TGFβR). Mitogen-activated protein kinase kinases (MAP2Ks) are substrates for direct phosphorylation by the MAP3K1 protein kinase. The MAP3K1 kinase domain...
    33 KB (3,167 words) - 18:40, 3 December 2023
  • Thumbnail for Protein synthesis inhibitor
    Trigger a Ribotoxic Stress Response That Activates c-Jun N-terminal Kinase and p38 Mitogen-activated Protein Kinase and Induces Apoptosis". Journal of Biological...
    11 KB (1,026 words) - 19:19, 25 April 2024
  • Thumbnail for MAP2K4
    MAP2K4 (category Mitogen-activated protein kinases)
    Dual-specificity mitogen-activated protein kinase kinase 4 is an enzyme that in humans is encoded by the MAP2K4 gene. MAP2K4 encodes a dual-specificity kinase that...
    9 KB (1,031 words) - 06:03, 11 March 2024
  • Thumbnail for MAP2K7
    MAP2K7 (category Mitogen-activated protein kinases)
    Dual specificity mitogen-activated protein kinase kinase 7, also known as MAP kinase kinase 7 or MKK7, is an enzyme that in humans is encoded by the MAP2K7...
    23 KB (2,694 words) - 17:22, 17 July 2024