humans is encoded by the PDCD1LG2 gene. PDCD1LG2 has also been designated as CD273 (cluster of differentiation 273). PDCD1LG2 is an immune checkpoint receptor...
19 KB (2,040 words) - 16:36, 5 January 2024
names Binds to B7-1 CD80 CD28, CTLA-4, PD-L1 B7-2 CD86 CD28, CTLA-4 B7-DC PDCD1LG2, PD-L2, CD273 PD-1 B7-H1 PD-L1, CD274 PD-1 B7-H2 ICOSLG, B7RP1, CD275 ICOS...
5 KB (637 words) - 09:45, 14 March 2022
activation inhibits the function of CD8+ cancer-specific T cells. CD273 PDL2 or PDCD1LG2 (Programmed Cell Death 1 Ligand 2); on Dendritic cells, Macrophages etc...
96 KB (467 words) - 19:33, 6 August 2024
HGNC:14634 Q13442 11841 PDC HGNC:8759 P20941 11842 PDCD1 HGNC:8760 Q15116 11843 PDCD1LG2 HGNC:18731 Q9BQ51 11844 PDCD2 HGNC:8762 Q16342 11845 PDCD2L HGNC:28194...
282 KB (17 words) - 18:42, 6 October 2024
CD8A, CMKLR1, CXCL9, CXCR6, HLA-DQA1, HLA-DRB1, HLA-E, IDO1, LAG3, NKG7, PDCD1LG2 (PDL2), PSMB10, STAT1, and TIGIT. A simple 2 gene mean expression score...
19 KB (2,430 words) - 23:03, 18 February 2024
mutations in KRAS, ARID1A, and PTEN genes; amplification of CD274 and PDCD1LG2 immune checkpoint genes; alterations to genes including MED1, ERBB3, CASP8...
82 KB (7,468 words) - 19:06, 19 April 2024
neoplastic B cells in PT-DLBCL also show gains and amplifications of CD274 and PDCD1LG2, which are the genes for the pro-death ligands, PDL1 and PDL2, respectfully...
22 KB (2,625 words) - 15:15, 29 December 2023