phosphodiesterase gamma-2 is an enzyme that in humans is encoded by the PLCG2 gene. From OMIM as of March 24, 2020: Enzymes of the phospholipase C family...
12 KB (1,405 words) - 12:49, 23 December 2023
immune dysregulation, first described in 2012. The name is an acronym of "PLCG2-associated antibody deficiency and immune dysregulation". It is characterised...
6 KB (711 words) - 20:19, 17 May 2023
phospholipase C-gamma2 (PLCG2), an enzyme involved in the activation of immune cells. The investigators have named the condition PLCG2-associated antibody...
23 KB (2,547 words) - 18:38, 12 July 2024
has been shown to interact with: ARID3A BLNK (SLP-65), CAV1, GNAQ, GTF2I, PLCG2, PRKD1, and SH3BP5. GRCh38: Ensembl release 89: ENSG00000010671 – Ensembl...
22 KB (2,389 words) - 06:43, 22 April 2024
ITK; JAK2; LCK; LCP2; LYN MATK; NCK1; NCK2 PIK3R1; PIK3R2; PIK3R3; PLCG1; PLCG2; PTK6; PTPN11; PTPN6; RASA1 SH2B1; SH2B2; SH2B3; SH2D1A; SH2D1B; SH2D2A;...
13 KB (1,341 words) - 04:09, 6 March 2024
Q9BRC7 12286 PLCE1 HGNC:17175 Q9P212 12287 PLCG1 HGNC:9065 P19174 12288 PLCG2 HGNC:9066 P16885 12289 PLCH1 HGNC:29185 Q4KWH8 12290 PLCH2 HGNC:29037 O75038...
282 KB (17 words) - 07:55, 20 June 2024
activation of a tyrosine kinase cascade finally to the activation of PLC-gamma2 (PLCG2) and more calcium release.[citation needed] Tissue factor also binds to...
70 KB (8,509 words) - 01:01, 31 July 2024
have up to 30 PLC enzymes. beta: PLCB1, PLCB2, PLCB3, PLCB4 gamma: PLCG1, PLCG2 delta: PLCD1, PLCD3, PLCD4 epsilon: PLCE1 eta: PLCH1, PLCH2 zeta: PLCZ1...
25 KB (2,691 words) - 00:59, 17 April 2024
interactions between BLNK and the SH2 domain-containing proteins Grb2, PLCG2, Btk, the Vav protein family, and Nck. BLNK has also been shown to interact...
24 KB (2,759 words) - 14:46, 26 January 2024
OSBPL9, PHLDA2, PHLDA3, PHLDB1, PHLDB2, PHLPP, PIP3-E, PLCD1, PLCD4, PLCG1, PLCG2, PLCH1, PLCH2, PLCL1, PLCL2, PLD1, PLD2, PLEK, PLEK2, PLEKHA1, PLEKHA2,...
14 KB (1,434 words) - 15:11, 10 June 2024
Activation of the gamma isoforms of phospholipase C (PLCγ) (see PLCG1 and PLCG2 illustrates one mechanism by which FGFR1 activates cell stimulating pathways...
44 KB (5,003 words) - 08:59, 15 July 2024
T-cell receptor (TCR) (PLCG1[citation needed]) or B-cell receptor (BCR) (PLCG2[citation needed]). This activation leads to release of inositol-1,4,5-triphosphate...
23 KB (2,877 words) - 23:41, 26 April 2024
functioning. PLCB1; PLCB2; PLCB3; PLCB4; PLCD1; PLCD3; PLCD4; PLCE1; PLCG1; PLCG2; PLCH1; PLCH2; PLCL1; PLCL2; PLCZ1 Clostridium perfringens alpha toxin Lipid...
18 KB (2,216 words) - 15:24, 26 August 2023
BCAR1, CD117, CD22, Cdk1, DOK1, EPOR GPVI, INPP5D, IRS1, LCP2, MUC1, NEDD9, PLCG2, PPP1R15A, PTPRC, Syk, TRPV4, UNC119, Lyn-CD22-SHP-1 pathway GRCh38: Ensembl...
32 KB (3,807 words) - 13:31, 4 April 2024
PLA2G4F; PLCB1; PLCB2; PLCB3; PLCB4; PLCD1; PLCD3; PLCD4; PLCE1; PLCG1; PLCG2; PLCH1; PLCH2; PLCL1; PLCL2; PLCZ1; PRF1; PRKCA; PRKCB1; PRKCE; PRKCG; PRKCH;...
11 KB (1,059 words) - 16:49, 31 July 2024
N-myritstoyltransferase 1 NMT1 Used to maintain localization Phospholipase C gamme 1 PLCG2 Enable protein kinase activity Regulator of Telomere elongation helicase...
5 KB (375 words) - 09:10, 17 January 2024
IRS1, Janus kinase 1, Janus kinase 2, LAIR1, LRP1, PDGFRB, PI3K → Akt PLCG2, PTK2B, Ras SLAMF1, SOCS3, SOS1, STAT3, STAT5A, and STAT5B. CagA is a protein...
37 KB (4,304 words) - 05:41, 17 June 2024