• Thumbnail for PRMT1
    arginine N-methyltransferase 1 is an enzyme that in humans is encoded by the PRMT1 gene. The HRMT1L2 gene encodes a protein arginine methyltransferase that...
    15 KB (1,751 words) - 14:47, 10 April 2024
  • Thumbnail for HBx
    methyltransferase 1 (PRMT1) was found to be associated with changes in transcription due to the methyltransferase function of PRMT1. Overexpression causes...
    14 KB (1,563 words) - 14:36, 3 December 2023
  • Thumbnail for Chromatin target of prmt1
    Chromatin target of PRMT1 is a protein that in humans is encoded by the CHTOP gene. This gene encodes a small nuclear protein that is characterized by...
    3 KB (363 words) - 01:22, 8 April 2022
  • Thumbnail for Histone H4
    H4 by PRMT1 was sufficient to permit subsequent acetylation on the N-terminal tail. However, acetylation of H4 inhibits its methylation by PRMT1. Acetylation...
    14 KB (1,585 words) - 23:41, 31 March 2024
  • Thumbnail for PRMT3
    "PRMT 3, a type I protein arginine N-methyltransferase that differs from PRMT1 in its oligomerization, subcellular localization, substrate specificity...
    3 KB (340 words) - 06:49, 18 December 2023
  • Thumbnail for P53
    An W, Kim J, Roeder RG (June 2004). "Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53". Cell. 117 (6): 735–48...
    124 KB (13,220 words) - 11:01, 30 August 2024
  • HGNC:9447 P04553 12845 PRM2 HGNC:9448 P04554 12846 PRM3 HGNC:13732 Q9NNZ6 12847 PRMT1 HGNC:5187 Q99873 12848 PRMT2 HGNC:5186 P55345 12849 PRMT3 HGNC:30163 O60678...
    282 KB (17 words) - 07:55, 20 June 2024
  • Thumbnail for Chromosome 1
    like CENPL: Centromere protein L CENPF (1q41) CHTOP: Chromatin target of prmt1 CNIH4: cornichon homolog 4 CNST: Consortin CREG1: Cellular repressor of...
    46 KB (3,290 words) - 20:16, 17 August 2024
  • Thumbnail for Histone methyltransferase
    can occur at arginine residues on histone tails. The first type of PRMTs (PRMT1, PRMT3, CARM1⧸PRMT4, and Rmt1⧸Hmt1) produce monomethylarginine and asymmetric...
    19 KB (2,214 words) - 12:18, 4 April 2024
  • Thumbnail for Protein detoxification
    methylated arginine derivatives Protein arginine N-methyltransferase 1 (PRMT1) Dimethylarginine dimethylaminohydrolase (DDAH) Asymmetric dimethylarginine...
    12 KB (1,233 words) - 20:06, 7 May 2021
  • Thumbnail for Stress granule
    Xie M, Zhang H, et al. (January 2020). "UBAP2L arginine methylation by PRMT1 modulates stress granule assembly". Cell Death and Differentiation. 27 (1):...
    183 KB (12,458 words) - 20:40, 1 July 2024
  • different classes of protein arginine methyltransferases (PRMTs): Type I PRMTs (PRMT1, PRMT2, PRMT3, PRMT4, PRMT6, and PRMT8) attach two methyl groups to a single...
    17 KB (2,016 words) - 16:32, 21 April 2024
  • Thumbnail for RNA-binding protein FUS
    symptoms. FUS has been shown to interact with: FUSIP1/SRSF10 HDAC1 ILF3, PRMT1, RELA, RNA polymerase II (C-terminal domain) SPI1, and TNPO1. GRCh38: Ensembl...
    32 KB (3,968 words) - 12:51, 13 May 2024
  • Thumbnail for Coronavirus nucleocapsid protein
    protein is arginine methylated by protein arginine methyltransferase 1 (PRMT1) at residues R95 and R177. Type I PRMT inhibitor (MS023) or substitution...
    25 KB (2,547 words) - 15:01, 22 August 2024
  • number of regulators in epidermal homeostasis, including ZNF750, MAF, MAFB, PRMT1, CSNK1A1, EHF, MPZL3, FDXR, TINCR, and ACTL6A. It uncovered new regulators...
    19 KB (1,802 words) - 14:54, 15 July 2024
  • Thumbnail for Protein BTG1
    proliferation. BTG1 has been shown to interact with: CNOT7, CNOT8, HOXB9, and PRMT1. Recurrent mutations in this gene have been associated to cases of diffuse...
    16 KB (1,792 words) - 09:04, 9 October 2023
  • Thumbnail for Protein BTG2
    target for medulloblastoma therapy. BTG2 has been shown to interact with PRMT1, HOXB9, CNOT8 and HDAC1 HDAC4 and HDAC9. It has also been studied with Pax6...
    26 KB (3,182 words) - 08:36, 6 May 2024
  • Thumbnail for HNRNPK
    HNRPK has been shown to interact with: CSK, DDX1, HNRNPL, KHDRBS1, PCBP2, PRMT1, and PTBP1. AKAP1; ANKHD1; ANKRD17; ASCC1; BICC1; DDX43; DDX53; DPPA5; FMR1;...
    17 KB (2,012 words) - 15:40, 22 December 2023
  • Thumbnail for EP300
    An W, Kim J, Roeder RG (June 2004). "Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53". Cell. 117 (6): 735–48...
    37 KB (4,263 words) - 08:33, 20 June 2024
  • Thumbnail for PABPN1
    protein II and in vitro methylation by protein arginine methyltransferases PRMT1 and PRMT3". J. Biol. Chem. 274 (19): 13229–34. doi:10.1074/jbc.274.19.13229...
    10 KB (1,214 words) - 02:06, 8 April 2024
  • Thumbnail for SERBP1
    Passos DO; Bressan GC; Nery FC; Kobarg J (2006). "Ki-1/57 interacts with PRMT1 and is a substrate for arginine methylation". FEBS J. 273 (17): 3946–61...
    8 KB (1,034 words) - 20:03, 8 April 2022
  • Thumbnail for DNA demethylation
    Y, Ponder BA, Nakamura Y, Hamamoto R (February 2011). "Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types...
    42 KB (5,154 words) - 13:37, 14 February 2024
  • Thumbnail for SUPT5H
    interact with: CDK9, Cyclin-dependent kinase 7, HTATSF1, PIN1, POLR2A, PRMT1 and Protein arginine methyltransferase 5. GRCh38: Ensembl release 89: ENSG00000196235...
    10 KB (1,231 words) - 02:49, 19 December 2023
  • and lysine 36 of histone H3 (Set2/SETD2) and arginine 3 of histone H4 (PRMT1). Strahl also helped to develop the first antibodies for methylated histones...
    19 KB (1,913 words) - 01:32, 28 July 2024
  • Thumbnail for HNRNPR
    PC4 and Mediator cofactors. HNRNPR has been shown to interact with SMN1, PRMT1, TDP-43, and FUS/TLS. ENSG00000125944 GRCh38: Ensembl release 89: ENSG00000282958...
    11 KB (1,425 words) - 03:34, 29 November 2023
  • Thumbnail for RNA Helicase A
    interact with: AKAP8L, BRCA1, DDX17 (p72) DDX5 (p68), KHDRBS1, MIZF, NXF1, PRMT1, RELA, and SMN1. GRCh38: Ensembl release 89: ENSG00000135829 – Ensembl,...
    14 KB (1,658 words) - 17:06, 27 August 2024
  • Thumbnail for CNOT7
    MC, Corbo L, Le Romancer M (February 2007). "hCAF1, a new regulator of PRMT1-dependent arginine methylation". J. Cell Sci. 120 (Pt 4): 638–47. doi:10...
    10 KB (1,308 words) - 08:33, 10 February 2024
  • Thumbnail for SHLD1
    citing yeast two-hybrid screenings have found C20orf196 to interact with PRMT1, QARS, MAD2L2, and CUL3. C20orf196 functionally interacts with REV7, SHLD2...
    14 KB (1,446 words) - 01:25, 3 December 2023
  • Thumbnail for Yi Zhang (biochemist)
    characterize six histone methyltransferases, including the H4R3 methyltransferase PRMT1, the H3K79 methyltransferase Dot1L, and the H3K27me3 methyltransferase EZH2/PRC2...
    26 KB (2,626 words) - 03:58, 4 September 2024
  • Thumbnail for ILF3
    found for this gene. ILF3 has been shown to interact with: DNA-PKcs, FUS, PRMT1 Protein kinase R, and XPO5. C5orf36 Small NF90/ILF3-associated RNAs (snaR)...
    16 KB (1,995 words) - 19:12, 22 August 2024