• Thumbnail for Pachyonychia congenita
    Pachyonychia congenita (often abbreviated as "PC") is a rare group of autosomal dominant skin disorders that are caused by a mutation in one of five different...
    13 KB (1,379 words) - 06:06, 11 April 2024
  • Thumbnail for Keratin 17
    protein lead to PC-K17 (previously known as Jackson-Lawler) type pachyonychia congenita and steatocystoma multiplex. Keratin 17 has been shown to interact...
    10 KB (1,197 words) - 17:43, 14 August 2024
  • Thumbnail for Keratin 16
    protein are associated with the genetic skin disorders including pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar...
    8 KB (1,088 words) - 17:41, 14 August 2024
  • Thumbnail for Keratoderma
    palmoplantar keratoderma Papillon–Lefèvre syndrome Pachyonychia congenita type I Pachyonychia congenita type II Focal palmoplantar keratoderma with oral...
    4 KB (241 words) - 21:28, 6 June 2024
  • Thumbnail for Genodermatosis
    syndrome. Almost 1 in 50,000 people has epidermolysis bullosa. Pachyonychia congenita is a rare type of genodermatosis, its clinical manifestations are...
    23 KB (2,533 words) - 22:50, 24 July 2024
  • Thumbnail for Keratin 6A
    expressing this protein is associated with the PC-K6A subtype of pachyonychia congenita, an inherited disorder of the epithelial tissues in which keratin...
    6 KB (868 words) - 16:41, 18 September 2021
  • Thumbnail for Steatocystoma multiplex
    et al. (1997). "Missense mutations in keratin 17 cause either pachyonychia congenita type 2 or a phenotype resembling steatocystoma multiplex". J. Invest...
    6 KB (633 words) - 07:32, 22 October 2023
  • Thumbnail for Ectodermal dysplasia
    syndrome/Dermatopathia pigmentosa reticulariss is associated with KRT14. Pachyonychia congenita is caused by multiple keratins. Focal dermal hypoplasia is associated...
    11 KB (1,167 words) - 10:46, 15 July 2024
  • Thumbnail for Pili torti
    keratoderma syndrome, oculo-dento-digital syndrome, pachyonychia congenita-2, Rapp-Hodgkin syndrome, Reeds syndrome, Salamon syndrome, Schöpf-Schulz-Passarge...
    48 KB (4,439 words) - 14:50, 2 October 2024
  • biomedical image processing Pubococcygeus muscle Parietal cell Pachyonychia congenita, a genetic skin disorder Pancreatic cancer Prostate cancer Palliative...
    8 KB (927 words) - 17:31, 14 November 2024
  • Thumbnail for Palmoplantar keratoderma
    dominant keratoderma that represents a clinical overlap syndrome with pachyonychia congenita type I but without the classic nail involvement.: 510  Punctate...
    20 KB (2,032 words) - 21:27, 12 August 2024
  • Thumbnail for RNA interference
    NCT00689065 TD101 K6a (N171K mutation) Naked siRNA Pachyonychia congenita I Completed Pachyonychia Congenita Project NCT00716014 AGN211745 VEGFR1 Naked siRNA...
    140 KB (15,409 words) - 05:20, 20 November 2024
  • Thumbnail for List of skin conditions
    Touraine) Pachyonychia congenita type I (Jadassohn–Lewandowsky syndrome) Pachyonychia congenita type II (Jackson–Lawler pachyonychia congenita, Jackson–Sertoli...
    198 KB (17,956 words) - 10:27, 2 November 2024
  • Thumbnail for Leukoplakia
    (see: Leukoplakia with tylosis and esophageal carcinoma). Dyskeratosis congenita may be associated with leukoplakia of the oral mucosa and of the anal...
    61 KB (6,922 words) - 16:48, 12 November 2024
  • subtype of pachyonychia congenita. McLean WH, Rugg EL, Lunny DP, et al. (March 1995). "Keratin 16 and keratin 17 mutations cause pachyonychia congenita". Nat...
    2 KB (246 words) - 07:49, 18 August 2023
  • also Health Exercise Nutrition Pachydermoperiostosis Pachygyria Pachyonychia congenita Jackson–Lawler type Pacman dysplasia Paes–Whelan–Modi syndrome Paget...
    24 KB (1,908 words) - 03:34, 11 January 2024
  • include:[citation needed] Palmoplantar ectodermal dysplasia type 1 or Pachyonychia congenita type I Palmoplantar ectodermal dysplasia type 3 or Acrokeratoelastoidosis...
    2 KB (102 words) - 03:28, 22 April 2024
  • Thumbnail for Keratin 6C
    Schwartz ME, Rittié L (2014). "Pachyonychia congenita cornered: report on the 11th Annual International Pachyonychia Congenita Consortium Meeting". Br. J...
    5 KB (658 words) - 19:49, 13 August 2023
  • skin disorders, including psoriasis, epidermolysis bullosa, and pachyonychia congenita. Type I keratin Schweizer, Jürgen; Bowden, Paul E.; Coulombe, Pierre...
    8 KB (922 words) - 17:09, 27 September 2023
  • palmoplantar verrucous nevus is a cutaneous condition that has features of pachyonychia congenita. Unilateral nevoid telangiectasia List of cutaneous conditions Rapini...
    1 KB (51 words) - 04:46, 5 May 2024
  • Thumbnail for Josef Jadassohn
    onychogryposis, hyperkeratosis, leukoplakia, hyperhidrosis and pachyonychia congenita. Nevus Sebaceous of Jadassohn: yellow-orange flat plaque, occurring...
    4 KB (367 words) - 00:10, 29 December 2023
  • EIF2B5 Pachyonychia congenita Jackson Lawler type; 167210; KRT17 Pachyonychia congenita Jackson Lawler type; 167210; KRT6B Pachyonychia congenita, Jadassohn-Lewandowsky...
    234 KB (18,877 words) - 06:16, 6 November 2024
  • domain Drug Indication Target Ocular and retinal disorders TD101 Pachyonychia congenita Keratin 6A N171K mutant Ocular and retinal disorders QPI-1007 Non-arteritic...
    47 KB (5,449 words) - 12:35, 27 October 2024
  • Papillon–Lefèvre syndrome Haim–Munk syndrome Premature dentition (Natal teeth) Pachyonychia congenita type II Grey–green discoloration of the mid-portion of permanent...
    3 KB (160 words) - 11:27, 1 September 2024
  • hydroxychloroquine. Pachyonychia Congenita. The Pachyonychia Congenita Quality of Life (PCQoL) was developed in 2012 to determine the effect Pachyonychia Congenita has...
    72 KB (8,434 words) - 06:04, 1 January 2024
  • Thumbnail for Keratin disease
    Siemens skin KRT2A Palmoplantar keratoderma skin KRT1, KRT9, KRT16 Pachyonychia congenita skin KRT6A, KRT6B, KRT16, KRT17 White sponge nevus skin KRT4, KRT13...
    3 KB (141 words) - 02:14, 7 May 2024
  • simplex Dowling–Degos' disease Olmsted syndrome 6a Pachyonychia congenita type I 6b Pachyonychia congenita type II 7 8 9 Diffuse epidermolytic palmoplantar...
    3 KB (161 words) - 16:22, 28 March 2023
  • Dowling–Degos' disease Olmsted syndrome KRT6A Pachyonychia congenita type I KRT6B Pachyonychia congenita type II KRT9 Diffuse epidermolytic palmoplantar...
    12 KB (108 words) - 02:46, 17 September 2022
  • Thumbnail for Gerodermia osteodysplastica
    gingival keratosis Howel–Evans syndrome Pachyonychia congenita Pachyonychia congenita type I Pachyonychia congenita type II Striate palmoplantar keratoderma...
    14 KB (1,449 words) - 16:00, 10 October 2024
  • Thumbnail for Irwin McLean
    epidermis, its appendages and other epithelial tissues, including pachyonychia congenita, muscular dystrophy with epidermolysis bullosa simplex and Meesmann...
    14 KB (1,060 words) - 12:24, 7 October 2024