• Palmitoyl-CoA is an acyl-CoA thioester. It is an "activated" form of palmitic acid and can be transported into the mitochondrial matrix by the carnitine...
    7 KB (612 words) - 20:33, 15 September 2024
  • Palmitoyl-CoA hydrolase (EC 3.1.2.2) is an enzyme in the family of hydrolases that specifically acts on thioester bonds. It catalyzes the hydrolysis of...
    7 KB (813 words) - 02:53, 24 May 2024
  • Thumbnail for Serine C-palmitoyltransferase
    enzyme that catalyzes the chemical reaction: palmitoyl-CoA + L-serine ⇌ {\displaystyle \rightleftharpoons } CoA + 3-dehydro-D-sphinganine + CO2 Thus, the...
    18 KB (1,755 words) - 20:13, 16 October 2024
  • Thumbnail for Stearoyl-CoA 9-desaturase
    acids (MUFAs), specifically oleate and palmitoleate from stearoyl-CoA and palmitoyl-CoA. Oleate and palmitoleate are major components of membrane phospholipids...
    27 KB (3,137 words) - 21:10, 29 June 2024
  • Thumbnail for Carnitine palmitoyltransferase I
    known as carnitine acyltransferase I, CPTI, CAT1, CoA:carnitine acyl transferase (CCAT), or palmitoylCoA transferase I, is a mitochondrial enzyme responsible...
    19 KB (2,464 words) - 00:31, 12 June 2024
  • Thumbnail for Carnitine palmitoyltransferase II deficiency
    mechanism in which the enzyme must bind CoA before palmitoylcarnitine, and then the resulting product palmitoyl-CoA is the last substrate to be released...
    26 KB (3,163 words) - 15:55, 16 October 2024
  • Thumbnail for Carnitine O-palmitoyltransferase
    palmitoylcarnitine into palmitoyl-CoA. A related transferase is carnitine acyltransferase. Palmitoylcarnitine Palmitoyl CoA There are four different...
    2 KB (151 words) - 07:15, 20 October 2022
  • Thumbnail for Palmitoyl(protein) hydrolase
    Palmitoyl protein hydrolase/thioesterases is an enzyme (EC 3.1.2.22) that removes thioester-linked fatty acyl groups such as palmitate from modified cysteine...
    5 KB (446 words) - 01:39, 9 January 2024
  • involved in diverse cellular processes. Sphingosine is synthesized from palmitoyl CoA and serine in a condensation required to yield dihydrosphingosine. Dehydrosphingosine...
    4 KB (220 words) - 20:12, 19 July 2024
  • Thumbnail for Acetyl-CoA carboxylase
    short chain fatty acyl-CoAs are negative feedback inhibitors of ACC. One such negative allosteric modulator is palmitoyl-CoA. Phosphorylation can result...
    27 KB (2,990 words) - 21:27, 4 July 2024
  • Thumbnail for Bombykol
    receptor. Bombykol is known to be derived from acetyl-CoA via the C-16 fatty acyl palmitoyl-CoA. Palmitoyl-CoA is converted to bombykol in steps that involve...
    8 KB (714 words) - 23:07, 8 May 2024
  • reaction palmitoyl-CoA + ecdysone ⇌ {\displaystyle \rightleftharpoons } CoA + ecdysone palmitate Thus, the two substrates of this enzyme are palmitoyl-CoA and...
    1 KB (128 words) - 13:56, 26 August 2023
  • Thumbnail for Palmitoylcarnitine
    Palmitoyl-CoA. Palmitoyl-CoA has the ability to freely pass the outer mitochondrial membrane, but the inner membrane is impermeable to the Acyl-CoA and...
    6 KB (599 words) - 05:24, 3 January 2024
  • Thumbnail for Long-chain-fatty-acid—CoA ligase
    this mechanism two products are released, AMP and acyl coa product. (Step 4, Figure 2) Acyl CoA is formed from long chain fatty acids through an acyl substitution...
    23 KB (2,740 words) - 19:59, 29 August 2024
  • Thumbnail for Fatty-acyl-CoA synthase
    mechanism consumes an acetyl coenzyme A (acetyl-CoA) and seven malonyl-CoA molecules to produce a palmitoyl-CoA. Synthesis of fatty acids is generally performed...
    15 KB (1,675 words) - 08:43, 10 July 2024
  • converted into acetyl-CoA. The overall net reaction, using palmitoyl-CoA (16:0) as a model substrate is: 7 FAD + 7 NAD+ + 7 CoASH + 7 H2O + H(CH2CH2)7CH2CO-SCoA...
    23 KB (2,461 words) - 05:56, 15 October 2024
  • occurs as feedback inhibition by palmitoyl-CoA and activation by citrate. When there are high levels of palmitoyl-CoA, the final product of saturated fatty...
    50 KB (5,561 words) - 07:03, 13 August 2024
  • catalyzes the chemical reaction palmitoyl-CoA + [myelin proteolipid] ⇌ {\displaystyle \rightleftharpoons } CoA + O-palmitoyl-[myelin proteolipid] Thus, the...
    2 KB (134 words) - 12:18, 26 August 2023
  • Thumbnail for Glutamate dehydrogenase
    inhibitors: Guanosine triphosphate (GTP) Adenosine triphosphate (ATP) Palmitoyl-CoA Zn2+ Activators: Adenosine diphosphate (ADP) Leucine l-isoleucine l-valine...
    15 KB (1,654 words) - 16:29, 28 July 2024
  • Thumbnail for Stearic acid
    In terms of its biosynthesis, stearic acid is produced from palmitoyl-CoA, with malonyl-CoA a two-carbon building block (after decarboxylation). Stearic...
    17 KB (1,568 words) - 08:03, 31 May 2024
  • enzyme that catalyzes the chemical reaction palmitoyl-CoA + glycoprotein ⇌ {\displaystyle \rightleftharpoons } CoA + N-palmitoylglycoprotein Thus, the two...
    2 KB (141 words) - 14:23, 26 August 2023
  • Thumbnail for Sphingomyelin
    of sphingomyelin synthesis involves the condensation of L-serine and palmitoyl-CoA. This reaction is catalyzed by serine palmitoyltransferase. The product...
    17 KB (1,972 words) - 21:12, 19 May 2024
  • Long-chain acyl-CoA dehydrogenase (EC 1.3.8.8, palmitoyl-CoA dehydrogenase, palmitoyl-coenzyme A dehydrogenase, long-chain acyl-coenzyme A dehydrogenase...
    4 KB (403 words) - 14:47, 26 August 2023
  • Thumbnail for Sphingolipid
    palmitoyltransferase. The preferred substrates for this reaction are palmitoyl-CoA and serine. However, studies have demonstrated that serine palmitoyltransferase...
    25 KB (2,774 words) - 16:47, 24 September 2024
  • Thumbnail for ACSL1
    for palmitoyl-CoA ligase (FACL1)". Cytogenetics and Cell Genetics. 59 (1): 17–9. doi:10.1159/000133189. PMID 1531127. "Entrez Gene: ACSL1 acyl-CoA synthetase...
    10 KB (1,256 words) - 16:24, 31 July 2024
  • reaction palmitoyl-CoA + dolichol ⇌ {\displaystyle \rightleftharpoons } CoA + dolichyl palmitate Thus, the two substrates of this enzyme are palmitoyl-CoA and...
    1 KB (116 words) - 13:54, 26 August 2023
  • Thumbnail for Ceramide
    3-keto-dihydrosphingosine. This reaction is catalyzed by the enzyme serine palmitoyl transferase and is the rate-limiting step of the pathway. In turn,...
    29 KB (3,310 words) - 03:20, 2 February 2024
  • Thumbnail for ACOT1
    acyl-CoA hydrolases, acyl-CoA thioester hydrolases, and palmitoyl-CoA hydrolases. The reaction carried out by these enzymes is as follows: CoA ester...
    9 KB (1,183 words) - 05:02, 8 March 2024
  • that catalyzes the chemical reaction palmitoyl-CoA + mucus glycoprotein ⇌ {\displaystyle \rightleftharpoons } CoA + O-palmitoylglycoprotein Thus, the two...
    1 KB (127 words) - 14:23, 26 August 2023
  • 3-oxoacyl-CoA + NADPH + H+ This microsomal complex extends palmitoyl-CoA and stearoyl-CoA (and their modified forms) to very-long-chain acyl CoAs. Beaudoin...
    2 KB (249 words) - 10:35, 5 January 2024