• Peptidoglycan or murein is a unique large macromolecule, a polysaccharide, consisting of sugars and amino acids that forms a mesh-like layer (sacculus)...
    36 KB (4,018 words) - 09:29, 10 June 2024
  • Thumbnail for Gram-positive bacteria
    bacteria have a thick layer of peptidoglycan within the cell wall, and Gram-negative bacteria have a thin layer of peptidoglycan. Gram-positive bacteria take...
    24 KB (2,655 words) - 23:06, 30 May 2024
  • Thumbnail for Lysozyme
    1.17, muramidase, N-acetylmuramide glycanhydrolase; systematic name peptidoglycan N-acetylmuramoylhydrolase) is an antimicrobial enzyme produced by animals...
    37 KB (4,285 words) - 13:40, 4 April 2024
  • Peptidoglycan glycosyltransferase (EC 2.4.1.129) is an enzyme used in the biosynthesis of peptidoglycan. It transfers a disaccharide-peptide from a donor...
    4 KB (402 words) - 18:17, 23 January 2024
  • Thumbnail for Gram stain
    thick layer of peptidoglycan in the cell wall that retains the primary stain, crystal violet. Gram-negative cells have a thinner peptidoglycan layer that...
    27 KB (2,795 words) - 20:47, 30 June 2024
  • Thumbnail for Cell wall
    agar, distinct from those in land plants. Bacterial cell walls contain peptidoglycan, while archaeal cell walls vary in composition, potentially consisting...
    43 KB (4,781 words) - 15:39, 10 June 2024
  • Thumbnail for Gram-negative bacteria
    defining characteristic is their cell envelope, which consists of a thin peptidoglycan cell wall sandwiched between an inner (cytoplasmic) membrane and an...
    24 KB (2,444 words) - 16:21, 29 May 2024
  • of peptidoglycan (poly-N-acetylglucosamine and N-acetylmuramic acid), which is located immediately outside of the cytoplasmic membrane. Peptidoglycan is...
    9 KB (1,169 words) - 03:12, 12 May 2024
  • Thumbnail for Peptidoglycan recognition protein
    Peptidoglycan recognition proteins (PGRPs) are a group of highly conserved pattern recognition receptors with at least one peptidoglycan recognition domain...
    110 KB (11,846 words) - 05:41, 6 May 2024
  • peptidoglycan GlcNAc deacetylase, peptidoglycan N-acetylglucosamine deacetylase, PG N-deacetylase) is an enzyme with systematic name peptidoglycan-N-acetylglucosamine...
    4 KB (380 words) - 15:19, 26 August 2023
  • Peptidoglycan β-N-acetylmuramidase (EC 3.2.1.92, exo-β-N-acetylmuramidase, exo-β-acetylmuramidase, β-2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-D-glucoside...
    1 KB (109 words) - 15:19, 26 August 2023
  • Thumbnail for Bacteria
    of peptidoglycan and teichoic acids. In contrast, Gram-negative bacteria have a relatively thin cell wall consisting of a few layers of peptidoglycan surrounded...
    143 KB (15,529 words) - 14:55, 10 July 2024
  • other organisms by the presence of peptidoglycan which is located immediately outside of the cell membrane. Peptidoglycan is made up of a polysaccharide backbone...
    36 KB (4,605 words) - 03:18, 12 May 2024
  • Thumbnail for Lipid II
    precursor molecule in the synthesis of the cell wall of bacteria. It is a peptidoglycan, which is amphipathic and named for its bactoprenol hydrocarbon chain...
    13 KB (1,324 words) - 22:06, 2 December 2023
  • Thumbnail for Beta-lactam antibiotics
    peptidoglycan precursors, which triggers the digestion of existing peptidoglycan by autolytic hydrolases without the production of new peptidoglycan....
    34 KB (3,702 words) - 00:59, 10 July 2024
  • Thumbnail for Peptidoglycan recognition protein 4
    Peptidoglycan recognition protein 4 (PGLYRP4, formerly PGRP-Iβ) is an antibacterial and anti-inflammatory innate immunity protein that in humans is encoded...
    27 KB (3,078 words) - 16:18, 23 March 2024
  • Thumbnail for Cefalexin
    the peptidoglycan layer of the bacterial cell wall. As cefalexin closely resembles d-alanyl-d-alanine, an amino acid ending on the peptidoglycan layer...
    25 KB (2,033 words) - 07:29, 1 July 2024
  • Thumbnail for Cephalosporin
    antibiotics, disrupt the synthesis of the peptidoglycan layer forming the bacterial cell wall. The peptidoglycan layer is important for cell wall structural...
    36 KB (2,500 words) - 21:09, 2 July 2024
  • Thumbnail for Glycopeptide antibiotic
    inhibit the synthesis of cell walls in susceptible microbes by inhibiting peptidoglycan synthesis. The core class (including vancomycin) binds to acyl-D-alanyl-D-alanine...
    9 KB (1,031 words) - 08:46, 22 May 2024
  • Thumbnail for N-acetylmuramoyl-L-alanine amidase
    bonds in linear amides. The systematic name of this enzyme class is peptidoglycan amidohydrolase. Other names in common use include acetylmuramyl-L-alanine...
    4 KB (291 words) - 15:03, 26 August 2023
  • Autolysins are endogenous lytic enzymes that break down the peptidoglycan components of biological cells which enables the separation of daughter cells...
    12 KB (1,393 words) - 23:33, 13 August 2023
  • Thumbnail for Peptidoglycan recognition protein 3
    Peptidoglycan recognition protein 3 (PGLYRP3, formerly PGRP-Iα) is an antibacterial and anti-inflammatory innate immunity protein that in humans is encoded...
    27 KB (3,087 words) - 16:19, 23 March 2024
  • Thumbnail for Pseudopeptidoglycan
    some Archaea that differs from bacterial peptidoglycan in chemical structure, but resembles bacterial peptidoglycan in function and physical structure. Pseudopeptidoglycan...
    9 KB (1,039 words) - 20:31, 1 February 2024
  • a peptidoglycan layer so do not retain crystal violet or safranin, resulting in no color. The Chlamydiaceae contain an extremely thin peptidoglycan layer...
    4 KB (427 words) - 20:16, 11 February 2023
  • (i.e. monoderm); they generally contain a thick layer (20-80 nm) of peptidoglycan responsible for retaining the Gram-stain. A number of other bacteria...
    20 KB (2,287 words) - 03:21, 23 March 2024
  • agglutinin disease. M. pneumoniae is characterized by the absence of a peptidoglycan cell wall and resulting resistance to many antibacterial agents. The...
    37 KB (4,014 words) - 21:20, 16 May 2024
  • Thumbnail for Cefpodoxime
    are no longer necessary for continued treatment. Cefpodoxime inhibits peptidoglycan synthesis in bacterial cell walls. It has an oral bioavailability of...
    6 KB (399 words) - 01:26, 14 May 2024
  • Thumbnail for Methicillin
    bacterial cell walls. It inhibits cross-linkage between the linear peptidoglycan polymer chains that make up a major component of the cell wall of gram-positive...
    8 KB (698 words) - 00:47, 29 April 2024
  • lipoproteins, it is linked covalently to the peptidoglycan. Lpp connects the outer membrane to the peptidoglycan. Lpp is anchored to the outer membrane by...
    5 KB (572 words) - 20:15, 15 December 2020
  • Thumbnail for Flucloxacillin
    bacterial cell walls. It inhibits cross-linkage between the linear peptidoglycan polymer chains that make up a major component of the cell wall of Gram-positive...
    23 KB (2,058 words) - 11:30, 1 July 2024