Plakophilin-2 is a protein that in humans is encoded by the PKP2 gene. Plakophilin 2 is expressed in skin and cardiac muscle, where it functions to link...
34 KB (4,002 words) - 22:48, 25 April 2024
Plakophilin-1 is a protein that in humans is encoded by the PKP1 gene. This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families...
8 KB (1,028 words) - 20:40, 3 March 2023
McDermott DA, et al. (November 2004). "Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy". Nature...
50 KB (5,441 words) - 04:00, 19 August 2024
van Roy F (April 2003). "Defining desmosomal plakophilin-3 interactions". The Journal of Cell Biology. 161 (2): 403–16. doi:10.1083/jcb.200303036. PMC 2172904...
13 KB (1,598 words) - 16:13, 15 August 2023
2007). "A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac...
42 KB (5,130 words) - 05:03, 14 August 2024
p120-catenin, plakoglobin (γ-catenin), and plakophilins 1-3. In desmosomes, plakoglobin and plakophilin help to anchor desmoplakin and keratin filaments...
10 KB (1,221 words) - 14:10, 30 August 2024
Plakophilin are proteins of the cytoskeleton. They are involved in regulating the adhesive activity of cadherin. The three types of plakophilin proteins...
2 KB (214 words) - 12:31, 23 October 2020
therapy for arrhythmogenic cardiomyopathy caused by mutations to the plakophilin-2 gene. It is delivered via adeno-associated virus and was developed by...
2 KB (196 words) - 11:34, 18 July 2024
junctional plaque protein plakophilin 3 in cytoplasmic particles containing RNA-binding proteins and the recruitment of plakophilins 1 and 3 to stress granules"...
183 KB (12,460 words) - 13:46, 23 September 2024
desmosomal cadherins bind to plakoglobin and plakophilins, which bind desmoplakin. In cardiac muscle, desmoglein-2 localizes to the intercalated disc, responsible...
20 KB (2,282 words) - 04:46, 19 August 2024
Plakophilin-4 is a protein that in humans is encoded by the PKP4 gene. Armadillo-like proteins are characterized by a series of armadillo repeats, first...
11 KB (1,333 words) - 21:17, 3 March 2023
Plakophilin-3 is a protein that in humans is encoded by the PKP3 gene. This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families...
6 KB (755 words) - 00:45, 4 March 2023
localization to the desmosome and interaction with the N-terminal region of plakophilin 1 and plakoglobin as well as desmocollin and desmoglein. This is further...
28 KB (3,242 words) - 15:17, 21 December 2023
proteins, such as calmodulin, calmodulin kinase II δc, ankyrin-G and plakophilin-2, are known to interact and modulate function of NaV1.5. Some of these...
25 KB (2,761 words) - 09:47, 21 September 2024
altered expression of proteins, including Neural Cadherin (CDH2) and Plakophilin-2 (PKP2), which naturally promote gap junction expression. Decreased CDH2...
22 KB (2,694 words) - 21:36, 13 July 2024
Striate palmoplantar keratoderma ARVD Plakophilin 1 Ectodermal dysplasia–skin fragility syndrome Plakophilin 2 ARVD Corneodesmosin Hypertrichosis simplex...
3 KB (170 words) - 01:59, 16 September 2024
"Arrhythmogenic right ventricular cardiomyopathy caused by deletions in plakophilin-2 and plakoglobin (Naxos disease) in families from Greece and Cyprus:...
40 KB (4,698 words) - 03:26, 19 August 2024
the first mutation responsible for sinus node disease and identified plakophilin-2 as the most common mutation underlying arrhythmogenic right ventricular...
31 KB (3,562 words) - 16:36, 2 July 2024
DSC2 (redirect from Desmocollin 2)
KJ (March 2002). "Protein binding and functional characterization of plakophilin 2. Evidence for its diverse roles in desmosomes and beta -catenin signaling"...
24 KB (2,560 words) - 03:18, 19 August 2024
"Super-resolution fluorescence microscopy of the cardiac connexome reveals plakophilin-2 inside the connexin43 plaque", Cardiovasc Res. 100 (2013) 231-240. doi:10...
7 KB (933 words) - 20:04, 18 April 2024
2017). "Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction". Nature Communications. 8: 13876. Bibcode:2017NatCo...
26 KB (2,146 words) - 02:36, 28 March 2024
et al. (2002). "Protein binding and functional characterization of plakophilin 2. Evidence for its diverse roles in desmosomes and beta -catenin signaling"...
7 KB (910 words) - 10:51, 24 December 2023
Skin fragility syndrome (redirect from Plakophilin 1 deficiency)
Skin fragility syndrome (also known as "plakophilin 1 deficiency") is a cutaneous condition characterized by trauma-induced blisters and erosions. It...
2 KB (114 words) - 21:54, 6 May 2024
Inagaki M (February 2002). "Densin-180 interacts with delta-catenin/neural plakophilin-related armadillo repeat protein at synapses". The Journal of Biological...
29 KB (3,399 words) - 17:34, 10 July 2024
Fibrillin (redirect from Fibrillin-2)
human body. Fibrillin-2 was isolated in 1994 by Zhang and is thought to play a role in early elastogenesis. Mutations in the fibrillin-2 gene have been linked...
7 KB (779 words) - 09:37, 10 March 2024
Microtubule-associated protein (section MAP2 (Type 2))
the MAP by the MARK causes the MAP to detach from any bound microtubules.[2] This detachment is usually associated with a destabilization of the microtubule...
12 KB (1,558 words) - 17:50, 6 July 2024
Alpha-actinin-2 is a protein which in humans is encoded by the ACTN2 gene. This gene encodes an alpha-actinin isoform that is expressed in both skeletal...
21 KB (2,601 words) - 17:21, 3 December 2023
Keratin 2A (redirect from Keratin 2)
Keratin 2A also known as keratin 2E or keratin 2 is a protein that in humans is encoded by the KRT2A gene. Keratin 2A is a type II cytokeratin. It is...
8 KB (1,107 words) - 06:13, 25 April 2024
Keratin (section Type 1 and 2 Keratins)
genes, 28 are in the Keratin type 1 family, and 26 are in the Keratin type 2 family. Fibrous keratin molecules supercoil to form a very stable, left-handed...
39 KB (3,017 words) - 13:44, 1 September 2024
A novel multiple PSD-95/Dlg-A/ZO-1 protein interacting with neural plakophilin-related armadillo repeat protein/delta-catenin and p0071". J. Biol. Chem...
5 KB (690 words) - 10:42, 23 July 2024