Platelet membrane glycoproteins are surface glycoproteins found on platelets (thrombocytes) which play a key role in hemostasis. When the blood vessel...
8 KB (1,110 words) - 10:45, 29 August 2021
GP1BA (category Membrane protein stubs)
in humans is encoded by the GP1BA gene. Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein receptor composed of a heterodimer, an alpha...
13 KB (1,545 words) - 06:16, 8 November 2023
GPVI is a 58-kD platelet membrane glycoprotein that plays a crucial role in the collagen-induced activation and aggregation of platelets. Upon injury to...
12 KB (1,419 words) - 11:02, 11 May 2024
biochemistry and medicine, glycoprotein IIb/IIIa (GPIIb/IIIa, also known as integrin αIIbβ3) is an integrin complex found on platelets. It is a transmembrane...
5 KB (500 words) - 06:24, 21 December 2023
small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib (GP Ib), a platelet surface...
8 KB (1,082 words) - 00:11, 14 May 2024
collagen receptors. Platelet membrane glycoproteins, mainly GPIa/IIa, GPVI and probably GPIV as well, function as receptors engaged in platelet adhesion to collagen...
8 KB (1,090 words) - 21:55, 30 September 2023
Membrane glycoproteins are membrane proteins which help in cell recognition, including fibronectin, laminin and osteonectin. Glycocalyx, a glycoprotein...
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complex is a profuse membrane receptor complex originating in megakaryocytes and exclusively functional on the surface of platelets. It primarily functions...
14 KB (1,648 words) - 22:47, 2 December 2023
or factors which lead to the adhesion of platelets to other platelets. Platelet membrane glycoprotein Platelet+adhesiveness at the U.S. National Library...
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protein on the surface of the platelet membrane that binds to vWF. When vWF is bound to glycoprotein lb, it helps the platelet interact with other surfaces...
9 KB (1,278 words) - 22:10, 30 October 2023
Glycoprotein Ib (platelet), beta polypeptide (GP1BB) also known as CD42c (Cluster of Differentiation 42c), is a protein that in humans is encoded by the...
11 KB (1,402 words) - 15:13, 3 December 2023
extracellular segments are also often glycosylated. Glycoproteins are also often important integral membrane proteins, where they play a role in cell–cell interactions...
28 KB (2,653 words) - 04:14, 23 July 2024
GP5 (gene) (category Membrane protein stubs)
Glycoprotein V (platelet) (GP5) also known as CD42d (Cluster of Differentiation 42d), is a human gene. Human platelet glycoprotein V (GP5) is a part of...
8 KB (1,000 words) - 17:40, 3 December 2023
platelet can be divided into four zones, from peripheral to innermost:[citation needed] Peripheral zone — rich in glycoproteins required for platelet...
71 KB (8,533 words) - 03:43, 8 September 2024
CD36 (category Membrane proteins)
also known as platelet glycoprotein 4, fatty acid translocase (FAT), scavenger receptor class B member 3 (SCARB3), and glycoproteins 88 (GP88), IIIb...
44 KB (5,085 words) - 19:02, 7 June 2024
In the membrane, they can be covalently bound to lipids to form glycolipids or covalently bound to proteins to form glycoproteins. Membranes contain...
19 KB (2,213 words) - 08:24, 22 August 2024
Coagulation (redirect from Platelet activation)
thromboxane A2, activate platelets in the bloodstream, leading to attachment of platelets' membrane receptors (e.g. glycoprotein IIb/IIIa) to extracellular...
67 KB (6,817 words) - 22:55, 7 August 2024
cases, antibodies against platelets can be detected. Most often these antibodies are against platelet membrane glycoproteins IIb-IIIa or Ib-IX, and are...
51 KB (5,807 words) - 16:34, 18 August 2024
Abciximab (category Glycoprotein IIb/IIIa inhibitors)
fragments of an immunoglobulin that targets the glycoprotein IIb/IIIa receptor on the platelet membrane. Abciximab is indicated for use in individuals...
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Red blood cell (redirect from Erythrocyte membrane)
– a glycoprotein that defines the Lutheran blood group and also known as Lu or laminin-binding protein. Structural role – The following membrane proteins...
64 KB (7,851 words) - 19:31, 4 September 2024
LAMP1 (redirect from Lysosomal-associated membrane protein 1)
Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a)...
19 KB (2,161 words) - 23:08, 4 September 2024
Chang, Mei-Chi (1998). "Antithormbotic Effect of Crotalin, a Platelet Membrane Glycoprotein Ib Antagonist From Venom of Crotalus atrox". Blood. 91 (5):...
36 KB (2,404 words) - 13:27, 5 September 2024
P-selectin glycoprotein ligand-1 (PSGL-1) is a glycoprotein found on white blood cells and endothelial cells that binds to P-selectin (P stands for platelet),...
11 KB (1,456 words) - 10:43, 5 January 2024
Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4) . This...
14 KB (1,641 words) - 23:08, 5 September 2024
P-selectin include CD62P, Granule Membrane Protein 140 (GMP-140), and Platelet Activation-Dependent Granule to External Membrane Protein (PADGEM). It was first...
20 KB (2,584 words) - 05:42, 5 September 2024
Von Willebrand factor (category Glycoproteins)
(VWF) (German: [fɔn ˈvɪləbʁant]) is a blood glycoprotein that promotes hemostasis, specifically, platelet adhesion. It is deficient and/or defective in...
17 KB (2,121 words) - 09:32, 20 August 2024
LAMP2 (redirect from Lysosomal-associated membrane protein 2)
lysosome-associated membrane glycoproteins. The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins...
16 KB (2,103 words) - 22:07, 22 December 2023
Ginsberg, M. H.; Plow, E. F.; Ruoslahti, E. (1986-03-28). "Platelet membrane glycoprotein IIb/IIIa: member of a family of Arg-Gly-Asp--specific adhesion...
36 KB (3,744 words) - 15:44, 15 March 2024
Apolipoprotein H (redirect from Beta-2 glycoprotein I)
J, Wurm H, Kostner GM (1985). "Interaction of beta 2-glycoprotein-I with human blood platelets: influence upon the ADP-induced aggregation". Thromb....
12 KB (1,419 words) - 19:08, 13 August 2023
and enlarged platelets, Bernard–Soulier syndrome is associated with quantitative or qualitative defects of the platelet glycoprotein complex GPIb/V/IX...
9 KB (867 words) - 16:56, 16 July 2024