A plexin is a protein which acts as a receptor for semaphorin family signaling proteins. It is classically known for its expression on the surface of axon...

Plexin-A1 is a protein that in humans is encoded by the PLXNA1 gene. Plexin A1 has been shown to interact with AKT1. GRCh38: Ensembl release 89: ENSG00000114554...

Plexin B1 is a protein of the plexin family that in humans is encoded by the PLXNB1 gene. Within neural tissues, the plexin family serves as transmembrane...

Plexin-A4 is a protein that in humans is encoded by the PLXNA4 gene. Plexin A4 binds to neuropilin 1 (Nrp1) and neuropilin 2 (Nrp2) and transduces signals...

(Sema6D) expressed at the midline, which form a complex that signals to Nr-CAM/Plexin-A1 receptors on crossing RGC axons. Since all vertebrates, even the earliest...

in mice that have a Plexin-A3 defect. Specifically, axons that are connected to a transient target will retract once the Plexin-A3 receptors are activated...

induces growth cone collapse in the central nervous system. By binding plexin B1 receptor it functions as an R-Ras GTPase-activating protein (GAP) and...

tyrosine kinase receptors, BMP7, Wnt/dishevelled, EPHB 1–3, Semaphorin/plexin-neuropilin, slit-robo, netrin-frazzled, reelin. Rac, CDC42 and RhoA serve...

Plexin-D1 is a protein that in humans is encoded by the PLXND1 gene. GRCh38: Ensembl release 89: ENSG00000004399 – Ensembl, May 2017 GRCm38: Ensembl release...

Plexin-B2 is a protein that in humans is encoded by the PLXNB2 gene. Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that...

Nakamura F, Wang LH, Murakami Y, Kalb RG, Fujisawa H, Strittmatter SM (1999). "Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors". Cell. 99...

Plexin-B3 is a protein that in humans is encoded by the PLXNB3 gene. PLXNB3 has been shown to interact with ARHGEF11. GRCh38: Ensembl release 89: ENSG00000198753...

the association of L1CAM with neuropilin-1. Neuropilin-1 interacts with Plexin-A proteins to form the Semaphorin-3A receptor complex. Semaphorin-a3A is...

also occur in the hepatocyte growth factor receptor (Uniprot: P08581), Plexin-A3 (Uniprot: P51805) and in viral proteins. CD100 (also called SEMA4D) is...

Plexin domain-containing protein 2 is a protein that in humans is encoded by the PLXDC2 gene. GRCh38: Ensembl release 89: ENSG00000120594 – Ensembl, May...

(Jul 2003). "Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells"...

Plexin-A3 is a protein that in humans is encoded by the PLXNA3 gene. GRCh38: Ensembl release 89: ENSG00000130827 – Ensembl, May 2017 GRCm38: Ensembl release...

PMID 15520858. Gu C, Yoshida Y, Livet J, et al. (2005). "Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins". Science. 307...

H (Mar 2003). "Identification and characterization of a novel mouse plexin, plexin-A4". Mechanisms of Development. 120 (3): 385–96. doi:10.1016/S0925-4773(02)00421-5...

Plexin domain-containing protein 1 is a protein that in humans is encoded by the PLXDC1 gene. Plexin PLXDC2 Protein domain GRCh38: Ensembl release 89:...

RGCs and the midline glia and acts along with Sema6D, mediated via the plexin-A1 receptor. VEGF-A is released from the midline directs RGCs to take a...

protein ORMDL sphingolipid biosynthesis regulator 3 PLXDC1: encoding protein Plexin domain-containing protein 1 PNPO: encoding enzyme Pyridoxine-5'-phosphate...

proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based...

Fournier A, Nakamura F, Wang LH, Murakami Y, Kalb RG, et al. (October 1999). "Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors". Cell. 99...

as Huntington's chorea, fragile X syndrome and myotonic dystrophy. CD232 Plexin-C1 (PLXNC1 gene); also called Virus-encoded semaphorin protein receptor...

embryonic organ development chemoattraction of axon commissural neuron axon guidance regulation of semaphorin-plexin signaling pathway Sources:Amigo / QuickGO...

Blondelle J, Singh MK, Flaherty KM, Means PC, et al. (August 2011). "Semaphorin-PlexinD1 signaling limits angiogenic potential via the VEGF decoy receptor sFlt1"...

(Jul 2003). "Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells"...

explored the role of the plexin receptor and the Rho family GTPases in central nervous system development in Drosophila. Plexins are receptors involved...

Plexin-A2 is a protein that in humans is coded by the PLXNA2 gene. This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins...