springs and hydrothermal vents, and Taq polymerase was identified as an enzyme able to withstand the protein-denaturing conditions (high temperature)...

bind the RNA polymerase responsible for transcription, either directly or through other mediator proteins; this locates the polymerase at the promoter...

The polymerase chain reaction (PCR) is a method widely used to make millions to billions of copies of a specific DNA sample rapidly, allowing scientists...

In molecular biology, RNA polymerase (abbreviated RNAP or RNApol), or more specifically DNA-directed/dependent RNA polymerase (DdRP), is an enzyme that...

Protein biosynthesis (or protein synthesis) is a core biological process, occurring inside cells, balancing the loss of cellular proteins (via degradation...

(October 1996). "Influenza virus polymerase basic protein 1 interacts with influenza virus polymerase basic protein 2 at multiple sites". J Virol. 70...

pairing can potentially result in dysfunctional proteins and could lead to cancer. Many DNA polymerases contain an exonuclease domain, which acts in detecting...

eukaryotic DNA polymerases and their accessory proteins". The Journal of Biological Chemistry. 266 (3): 1950–60. doi:10.1016/S0021-9258(18)52385-1. PMID 1671045...

heat-resistant enzyme Taq DNA polymerase, one of the most important enzymes in molecular biology because of its use in the polymerase chain reaction (PCR) DNA...

into structural proteins by host cell machinery. During replication of the negative-sense viral genome, RNA-dependent RNA polymerase synthesizes a positive-sense...

in the PR reading frame. The N protein is an antiterminator, and functions by engaging the transcribing RNA polymerase at specific sites of the nascently...

of proteins are associated with the replication fork to help in the initiation and continuation of DNA synthesis. Most prominently, DNA polymerase synthesizes...

terminators require a large protein called a Rho factor which exhibits RNA helicase activity to disrupt the mRNA-DNA-RNA polymerase transcriptional complex...

TFIIB recruits RNA polymerase II and TFIIF to the promoter. TFIIE joins the growing complex and recruits TFIIH which has protein kinase activity (phosphorylates...

secure initial binding site for RNA polymerase and for proteins called transcription factors that recruit RNA polymerase. These transcription factors have...

respectively. In the case of a repressor, the repressor protein physically obstructs the RNA polymerase from transcribing the genes. Structural genes – the...

real-time polymerase chain reaction (real-time PCR, or qPCR when used quantitatively) is a laboratory technique of molecular biology based on the polymerase chain...

Retrieved 2018-05-07. "PB2 - Polymerase basic protein 2 - Influenza A virus (strain A/Wilson-Smith/1933 H1N1) - PB2 gene & protein". www.uniprot.org. Retrieved...

primer may also be referred to as an oligo, short for oligonucleotide. DNA polymerase (responsible for DNA replication) enzymes are only capable of adding nucleotides...

recombinant protein under the control of the T7 promoter is 8x faster than protein expression under the control of E. coli RNA polymerase. Basal levels...

Protein phosphatase 1 (PP1) belongs to a certain class of phosphatases known as protein serine/threonine phosphatases. This type of phosphatase includes...

Basic helix-loop-helix ARNT-like protein 1 or aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL), or brain and muscle ARNT-like 1 is...

supported the sequencing of complex proteins. In 1999, Roger Kornberg sequenced the highly complex structure of RNA polymerase using high intensity X-rays from...

tertiary, and/or quaternary structures of proteins or nucleic acids resulting in a loss of bioactivity. Note 1: Modified from the definition given in ref...

RNA polymerase and other proteins for the successful initiation of transcription directly upstream of the gene. Operators recognize repressor proteins that...

factor 2 (FGF-2), also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by the FGF2 gene. It binds...

the terms and components used in the PCR process.) The history of the polymerase chain reaction (PCR) has variously been described as a classic "Eureka...

from DNA to messenger RNA. GTFs, RNA polymerase, and the mediator (a multi-protein complex) constitute the basic transcriptional apparatus that first...

H and N proteins in the viral envelope; for example, "H1N1" designates an IAV subtype that has a type-1 hemagglutinin (H) protein and a type-1 neuraminidase...

DNA-dependent DNA polymerases, RNA polymerase II, the enzyme that transcribes most of the genes in the human genome, operates as part of a large protein complex...