Pregnenolone (P5), or pregn-5-en-3β-ol-20-one, is an endogenous steroid and precursor/metabolic intermediate in the biosynthesis of most of the steroid...
21 KB (2,059 words) - 07:45, 3 June 2024
Pregnenolone, sold under the brand name Enelone among others, is a medication and supplement as well as a naturally occurring and endogenous steroid. It...
19 KB (1,579 words) - 16:06, 29 December 2023
Pregnenolone sulfate (PS, PREGS) is an endogenous excitatory neurosteroid that is synthesized from pregnenolone. It is known to have cognitive and memory-enhancing...
6 KB (370 words) - 18:49, 6 May 2023
Pregnenolone may refer to: Pregnenolone (pregn-5-en-3β-ol-20-one) Pregnenolone (medication) 3β-Dihydroprogesterone (pregn-4-en-3β-ol-20-one) 3α-Dihydroprogesterone...
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Pregnenolone acetate (brand names Antofin, Previsone, Pregno-Pan), also known as pregn-5-en-3β-ol-20-one 3β-acetate, is a synthetic pregnane steroid and...
4 KB (261 words) - 01:18, 12 November 2022
cholesterol with pregnenolone as a metabolic intermediate. In the first step in the steroidogenic pathway, cholesterol is converted into pregnenolone, which serves...
16 KB (1,567 words) - 13:48, 19 June 2024
3β-Methoxypregnenolone (redirect from Pregnenolone 3β-methyl ether)
MAP-4343), or pregnenolone 3β-methyl ether, also known as 3β-methoxypregn-5-en-20-one, is a synthetic neuroactive steroid and derivative of pregnenolone. It interacts...
4 KB (198 words) - 22:20, 3 December 2023
Pregnenolone succinate (USANTooltip United States Adopted Name; brand names Panzalone, Formula 405; also known as pregnenolone hemisuccinate or pregn-5-en-3β-ol-20-one...
6 KB (448 words) - 09:18, 28 December 2023
Pregnenolone 16α-carbonitrile (PCN) is a synthetic, steroidal antiglucocorticoid and pregnane X receptor agonist. Pregnenolone Mifepristone Ketoconazole...
3 KB (109 words) - 18:49, 6 May 2023
neuroprotective, and neurogenic effects. Major examples include the pregnanes pregnenolone sulfate (PS), epipregnanolone, and isopregnanolone (sepranolone), the...
41 KB (4,347 words) - 18:35, 7 April 2024
17α-Hydroxypregnenolone (redirect from 17-hydroxy-pregnenolone)
17α-Hydroxypregnenolone is a pregnane (C21) steroid that is obtained by hydroxylation of pregnenolone at the C17α position. This step is performed by the mitochondrial cytochrome...
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22-desmolase; converts cholesterol to pregnenolone. 17,20-Desmolase, also called CYP17A1 or 17α-hydroxylase; converts pregnenolone to 17α-hydroxypregnenolone, progesterone...
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Allopregnanolone is an endogenous inhibitory pregnane neurosteroid. It is made from pregnenolone, and is a positive allosteric modulator of the action of γ-aminobutyric...
50 KB (4,804 words) - 11:18, 26 January 2024
3β-Dihydroprogesterone (redirect from 4-pregnenolone)
known as 3β-hydroxyprogesterone, or pregn-4-en-3β-ol-20-one (4-pregnenolone, δ4-pregnenolone), is an endogenous steroid. It is biosynthesized by 3β-hydroxysteroid...
4 KB (334 words) - 01:24, 27 April 2023
steroidogenic enzyme P450scc that converts cholesterol to pregnenolone in the mitochondria. Pregnenolone is then converted to progesterone that is secreted out...
17 KB (1,684 words) - 21:14, 23 March 2024
in each sex at different levels. Sex hormones include: Progestogens Pregnenolone → Progesterone → Allopregnanedione → Allopregnanolone 17α-Hydroxypregnenolone...
7 KB (617 words) - 08:54, 11 June 2024
levels with age and age-related neurodegenerative diseases. Similarly to pregnenolone, its synthetic derivative 3β-methoxypregnenolone (MAP-4343), and progesterone...
42 KB (3,935 words) - 04:01, 30 April 2024
Opipramol Pentazocine Pentoxyverine (carbetapentane) PRE-084 Pregnenolone Pregnenolone sulfate Pridopidine Racemethorphan (methorphan) Racemorphan (morphanol)...
118 KB (11,401 words) - 16:22, 15 June 2024
Opipramol Pentazocine Pentoxyverine (carbetapentane) PRE-084 Pregnenolone Pregnenolone sulfate Pridopidine Racemethorphan (methorphan) Racemorphan (morphanol)...
165 KB (15,793 words) - 11:39, 10 June 2024
(3β-(4-methoxybenzyloxy)pregn-5-en-20-one) is a compound derived from pregnenolone by Aelis Farma, which acts as a biased allosteric modulator of the cannabinoid...
4 KB (297 words) - 21:39, 8 February 2024
acid GSK417651A GSK2293017A Meclofenamic acid N-(p-Amylcinnamoyl)anthranilic acid Niflumic acid Pregnenolone sulfate Progesterone Pyr3 Tolfenamic acid...
47 KB (5,224 words) - 06:34, 27 May 2024
finally the bond between carbons 20 and 22 is cleaved by P450scc to form pregnenolone ((3β)-3-hydroxypregn-5-en-20-one), the precursor to the steroid hormones...
3 KB (186 words) - 16:33, 26 April 2023
acid GSK417651A GSK2293017A Meclofenamic acid N-(p-Amylcinnamoyl)anthranilic acid Niflumic acid Pregnenolone sulfate Progesterone Pyr3 Tolfenamic acid...
18 KB (1,436 words) - 20:32, 26 June 2024
are 8 to 13 ng/dL. The placenta produces pregnenolone and progesterone from circulating cholesterol. Pregnenolone is taken up by the fetal adrenal glands...
22 KB (2,085 words) - 20:44, 16 March 2024
blue GYKI-52466 GYKI-53655 Halothane Irampanel Isoflurane Perampanel Pregnenolone sulfate Sevoflurane Talampanel; Unknown/unsorted antagonists: Minocycline...
143 KB (16,187 words) - 06:57, 23 June 2024
Opipramol Pentazocine Pentoxyverine (carbetapentane) PRE-084 Pregnenolone Pregnenolone sulfate Pridopidine Racemethorphan (methorphan) Racemorphan (morphanol)...
163 KB (17,896 words) - 23:54, 25 June 2024
androstenedione (A4), and neurosteroids like DHEA and DHEA-S, as well as pregnenolone and pregnenolone sulfate (P5-S). Adrenal steroids are specifically produced in...
11 KB (1,238 words) - 12:22, 24 January 2024
at position C22 to produce pregnenolone. This reaction is catalyzed by cytochrome P450scc. The conversion of pregnenolone to progesterone takes place...
123 KB (11,590 words) - 09:25, 11 May 2024
Pregnanediol Pregnanedione (5β-dihydroprogesterone) Pregnanolone Pregnenolone Pregnenolone 16α-carbonitrile Proadifen Progesterone Quingestrone Reserpine...
173 KB (16,053 words) - 02:28, 23 June 2024
Prednisolone esters Prednisone Prednisone esters Pregnenolone Pregnenolone acetate Pregnenolone succinate (pregnenolone hemisuccinate) Resocortol Tipredane Tixocortol...
41 KB (3,282 words) - 05:55, 27 May 2024