• In enzymology, a prolinetRNA ligase (EC 6.1.1.15) is an enzyme that catalyzes the chemical reaction ATP + L-proline + tRNAPro ⇌ {\displaystyle \rightleftharpoons...
    2 KB (212 words) - 15:32, 26 August 2023
  • EC 6.1.1.15: prolinetRNA ligase EC 6.1.1.16: cysteine—tRNA ligase EC 6.1.1.17: glutamate—tRNA ligase EC 6.1.1.18: glutamine—tRNA ligase EC 6.1.1.19:...
    25 KB (2,811 words) - 23:21, 22 July 2023
  • Thumbnail for Arginine—tRNA ligase
    in arginine and proline metabolism and aminoacyl-trna biosynthesis. It contains a conserved domain at the N terminus called arginyl tRNA synthetase N terminal...
    4 KB (348 words) - 16:28, 22 September 2024
  • Thumbnail for Ubiquitin ligase
    A ubiquitin ligase (also called an E3 ubiquitin ligase) is a protein that recruits an E2 ubiquitin-conjugating enzyme that has been loaded with ubiquitin...
    24 KB (2,755 words) - 04:56, 29 September 2024
  • Thumbnail for EPRS
    gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species. Phosphorylation of EPRS...
    10 KB (1,158 words) - 17:10, 27 December 2023
  • L-firefly luciferin-CoA ligase EC 6.2.1.53: L-proline-L-prolyl-carrier protein ligase EC 6.2.1.54: D-alanine-D-alanyl-carrier protein ligase EC 6.2.1.55: E1 SAMP-activating...
    33 KB (3,650 words) - 18:48, 10 September 2024
  • or advancement of the tRNA-mRNA complex by three nucleotides Translocation "kicks off" the tRNA at the E site and shifts the tRNA from the A site into...
    61 KB (6,770 words) - 15:11, 20 August 2024
  • C12H17ClN4OS·HCl Threonine Thrombopoietin Thromboxane Thymidine Thymine Transfer RNA (tRNA) Triacsin C Thyroid-stimulating hormone (TSH) Thyrotropin-releasing hormone...
    12 KB (933 words) - 20:02, 10 May 2023
  • Thumbnail for Chromosome 12
    enzyme tRNA (guanine-N(7)-)-methyltransferase MFAP5: encoding protein Microfibrillar-associated protein 5 MIR196A2: encoding microRNA MicroRNA 196a-2...
    27 KB (1,735 words) - 22:13, 28 March 2024
  • Thumbnail for C8orf58
    C8orf58 (section mRNA)
    (Methionine—tRNA ligase) is required for elongation of protein synthesis and the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation...
    7 KB (609 words) - 12:25, 14 February 2023
  • Thumbnail for Chromosome 1
    protein SMG7: nonsense mediated mRNA decay factor SMYD3 (1q44) SPG23 SPRR1A: Cornifin-A SPRR1B: Cornifin-B SPRR2A: Small proline rich protein 2A SPRTN: Spartan...
    46 KB (3,290 words) - 20:16, 17 August 2024
  • Thumbnail for Histone-modifying enzymes
    ADP-ribosylation, citrullination and proline isomerization. For a detailed example of histone modifications in transcription regulation see RNA polymerase control by...
    33 KB (3,157 words) - 04:31, 13 August 2024
  • Thumbnail for Post-translational modification
    C-terminal Gly residue. amide bond formation amino acid addition arginylation, a tRNA-mediation addition polyglutamylation, covalent linkage of glutamic acid residues...
    33 KB (3,189 words) - 03:12, 28 March 2024
  • Thumbnail for Stress granule
    Takeuchi O, Pandey S, Satoh T, Iwasaki H, Akira S, et al. (April 2014). "Pivotal role of RNA-binding E3 ubiquitin ligase MEX3C in RIG-I-mediated antiviral...
    183 KB (12,460 words) - 13:46, 23 September 2024
  • Thumbnail for Phosphoribosylamine—glycine ligase
    Phosphoribosylamine—glycine ligase, also known as glycinamide ribonucleotide synthetase (GARS), (EC 6.3.4.13) is an enzyme that catalyzes the chemical...
    12 KB (1,201 words) - 14:15, 22 September 2024
  • Thumbnail for Chromosome 19
    viral integration site ACSBG2: encoding enzyme Long-chain-fatty-acid—CoA ligase ANKRD24: encoding protein Ankyrin repeat domain-containing protein 24 ARMC6:...
    30 KB (2,547 words) - 01:46, 3 December 2023
  • Thumbnail for Chromosome 3
    phosphoinositide-3-kinase, catalytic, alpha polypeptide PISRT1: long non-coding RNA PROSER1: Proline and serine rich protein 1 RAB7: RAB7, member RAS oncogene family...
    34 KB (1,982 words) - 21:02, 24 August 2024
  • Thumbnail for P53
    Mason A, Carlson DM (September 1982). "Cell-free translations of proline-rich protein mRNAs". The Journal of Biological Chemistry. 257 (18): 11176–80. doi:10...
    124 KB (13,220 words) - 11:01, 30 August 2024
  • Thumbnail for Chromosome 2
    PCBP1 antisense RNA 1 PCYOX1: prenylcysteine oxidase 1 PELI1: Ubiquitin ligase PLGLB2: Plasminogen-related protein B POLR1A: DNA-directed RNA polymerase I...
    40 KB (2,534 words) - 05:56, 28 July 2024
  • Thumbnail for Chromosome 17
    receptor potential cation channel subfamily V member 1 TSEN54: encoding protein TRNA splicing endonuclease subunit 54 TTYH2: encoding protein Tweety family member...
    26 KB (1,923 words) - 23:13, 1 October 2024
  • Thumbnail for Citric acid cycle
    at least one of two critical proline residues mediates their interaction with the von Hippel Lindau E3 ubiquitin ligase complex, which targets them for...
    56 KB (6,065 words) - 13:22, 2 October 2024
  • Thumbnail for CBL (gene)
    the Cbl family, encodes the protein CBL which is an E3 ubiquitin-protein ligase involved in cell signalling and protein ubiquitination. Mutations to this...
    33 KB (3,814 words) - 13:11, 14 September 2024
  • Thumbnail for NEDD4
    E3 ubiquitin-protein ligase NEDD4, also known as neural precursor cell expressed developmentally down-regulated protein 4 (whence "NEDD4") is an enzyme...
    27 KB (3,414 words) - 21:44, 27 March 2024
  • Thumbnail for Von Hippel–Lindau tumor suppressor
    includes elongin B, elongin C, and cullin-2, and possesses E3 ubiquitin ligase activity. This complex is involved in the ubiquitination and subsequent...
    27 KB (3,282 words) - 18:16, 8 June 2024
  • Thumbnail for Hypothetical types of biochemistry
    scanning. A hypothetical "Proline World" would create a possible alternative life with the genetic code based on the proline chemical scaffold as the protein...
    79 KB (8,198 words) - 18:55, 15 September 2024
  • Schneider SN, Nebert DW, Dalton TP (October 2005). "Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue...
    6 KB (492 words) - 10:07, 7 November 2023
  • Thumbnail for ITCH
    ITCH is a HECT domain–containing E3 ubiquitin ligase that is ablated in non-agouti-lethal 18H (aka Itchy) mice. Itchy mice develop a severe immunological...
    9 KB (1,030 words) - 07:11, 3 April 2024
  • Thumbnail for WBP1
    Sudol M (Sep 1995). "The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology...
    4 KB (485 words) - 21:41, 20 February 2024
  • Thumbnail for Mitochondrial antiviral-signaling protein
    domain (CARD), a proline rich domain, and a transmembrane C terminal domain (TM). After the MAVS gene has been transcribed into RNA, ribosomes can translate...
    16 KB (1,931 words) - 19:24, 19 August 2024
  • Thumbnail for PELP-1
    Proline-, glutamic acid- and leucine-rich protein 1 (PELP1) also known as modulator of non-genomic activity of estrogen receptor (MNAR) and transcription...
    33 KB (3,909 words) - 02:04, 3 December 2023