A protein isoform, or "protein variant", is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result...
17 KB (2,013 words) - 01:16, 4 January 2024
Alternative splicing (redirect from Transcript isoform)
instance, isoform.io, a platform guided by protein structure predictions, has evaluated hundreds of thousands of isoforms of human protein-coding genes...
62 KB (7,809 words) - 17:56, 21 May 2024
The tau proteins (abbreviated from tubulin associated unit) form a group of six highly soluble protein isoforms produced by alternative splicing from...
56 KB (6,277 words) - 19:41, 6 July 2024
C13orf46 (section Protein isoform 1)
alternatively spliced mRNA transcript, which produce five different protein isoforms. An alternative name for C13orf46 is LOC100507747. C13orf46 spans 47...
34 KB (2,158 words) - 01:42, 10 March 2024
P53 (redirect from Protein P53)
to the full-length protein, the human TP53 gene encodes at least 12 protein isoforms. In humans, the TP53 gene is located on the short arm of chromosome...
123 KB (13,103 words) - 00:36, 26 June 2024
genetics, gene isoforms are mRNAs that are produced from the same locus but are different in their transcription start sites (TSSs), protein coding DNA sequences...
8 KB (992 words) - 18:28, 18 April 2024
HLA-DQ2 (section DQ2 isoforms and DQ2 haplotypes)
DQ2.5 haplotype. DQ2.5 refers to either a protein isoform and a genetic (chromosomal) haplotype. DQ2.5 isoform or heterodimer is shorthand for the cell...
33 KB (3,380 words) - 17:14, 6 July 2024
much easier for an organism to expand on a current gene/protein family (creating protein isoforms) than it is to create an entirely new gene. From an evolutionary...
51 KB (6,192 words) - 19:26, 10 May 2024
for any single G-protein to deactivate if other factors did not come into play. Indeed, there are around 30 isoforms of RGS proteins that, when bound...
82 KB (9,384 words) - 18:56, 11 June 2024
Factor VIII (category Acute-phase proteins)
large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple...
17 KB (2,027 words) - 17:05, 10 May 2024
chromosome 12q15, where the HMGIC gene encodes the high-mobility-group protein isoform I-C. This is one of the most commonly found mutations in solitary lipomatous...
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and most complete transcript of the gene, variant 1, encodes isoform 1 of the BEND2 protein (NP_699177.2). The untranslated regions (UTR) flanking the coding...
22 KB (1,795 words) - 20:14, 20 September 2023
(a)PKCs (including protein kinase Mζ and ι / λ isoforms) require neither Ca2+ nor diacylglycerol for activation. The term "protein kinase C" usually refers...
27 KB (2,650 words) - 21:16, 19 March 2024
fully edited isoform, VGV, considerably reduces 5-HT potency, G-protein coupling and agonist binding, compared to the unedited protein isoform, INI. 72–76...
51 KB (6,097 words) - 12:24, 28 June 2024
CCDC121 (section Isoforms and alternative splicing)
(CCDC121) is a protein encoded by the CCDC121 gene in humans. CCDC121 is located on the minus strand of chromosome 2 and encodes three protein isoforms. All isoforms...
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but occurs in many other tissues throughout the body. The protein can exist in multiple isoforms: the normal PrPC form, and the protease-resistant form designated...
45 KB (5,229 words) - 20:07, 27 June 2024
TEX9 (redirect from Testis-expressed protein 9)
"testis-expressed protein 9 isoform 1 [Homo sapiens] - Protein - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2019-02-08. "TEX9 - Testis-expressed protein 9 - Homo sapiens...
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Western blot (category Protein methods)
the potential to distinguish different protein isoforms, it may be used to diagnose prion and protein isoform-related diseases, such as cancer. For instance...
66 KB (8,077 words) - 10:16, 9 July 2024
ISLR (section Known isoforms)
the longest protein isoform with the length of 2,331 bp, containing 2 exons. Transcript variant 2 encodes for the shorter protein isoform with the length...
46 KB (4,000 words) - 02:01, 28 March 2024
of 3-ketosteroids into 3α-hydroxysteroids. The enzyme has various protein isoforms (isozymes). In humans, 3α-hydroxysteroid dehydrogenase is encoded by...
16 KB (1,731 words) - 22:28, 12 May 2024
Ser/Thr protein kinase homologous to the MRCK p21-activated kinases and Rho kinase family. Data obtained by using antibodies that detect specific isoforms of...
19 KB (2,426 words) - 16:47, 30 March 2024
C2orf74 (category Proteins)
also known as LOC339804, is a protein encoding gene located on the short arm of chromosome 2 near position 15 (2p15). Isoform 1 of the gene is 19,713 base...
22 KB (2,326 words) - 15:14, 29 April 2024
Protein folding, process by which a protein assumes its characteristic functional shape or tertiary structure Protein isoform, version of a protein with...
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Carling D (May 1998). "Identification of a novel AMP-activated protein kinase beta subunit isoform that is highly expressed in skeletal muscle". The Journal...
65 KB (7,147 words) - 05:41, 24 June 2024
structure of the cyclic GMP-dependent protein kinase I{beta} dimerization/docking domain reveals molecular details of isoform-specific anchoring". The Journal...
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C20orf27 (redirect from UPF0687 Protein C20orf27)
transcript variant 4. Transcript variant 1 encodes for the longest protein isoform, with a size of 1327 bases and 6 exons. Transcript variant 2 maintains...
31 KB (3,092 words) - 01:49, 10 March 2024
Amelogenin (category Protein pages needing a picture)
Amelogenins are a group of protein isoforms produced by alternative splicing or proteolysis from the AMELX gene, on the X chromosome, and also the AMELY...
7 KB (857 words) - 10:36, 1 December 2023