• Thumbnail for Protein isoform
    A protein isoform, or "protein variant", is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result...
    17 KB (2,013 words) - 01:16, 4 January 2024
  • Thumbnail for Alternative splicing
    instance, isoform.io, a platform guided by protein structure predictions, has evaluated hundreds of thousands of isoforms of human protein-coding genes...
    62 KB (7,809 words) - 17:56, 21 May 2024
  • Thumbnail for Tau protein
    The tau proteins (abbreviated from tubulin associated unit) form a group of six highly soluble protein isoforms produced by alternative splicing from...
    56 KB (6,277 words) - 19:41, 6 July 2024
  • Thumbnail for C13orf46
    alternatively spliced mRNA transcript, which produce five different protein isoforms. An alternative name for C13orf46 is LOC100507747. C13orf46 spans 47...
    34 KB (2,158 words) - 01:42, 10 March 2024
  • Thumbnail for P53
    P53 (redirect from Protein P53)
    to the full-length protein, the human TP53 gene encodes at least 12 protein isoforms. In humans, the TP53 gene is located on the short arm of chromosome...
    123 KB (13,103 words) - 00:36, 26 June 2024
  • genetics, gene isoforms are mRNAs that are produced from the same locus but are different in their transcription start sites (TSSs), protein coding DNA sequences...
    8 KB (992 words) - 18:28, 18 April 2024
  • Thumbnail for HLA-DQ2
    DQ2.5 haplotype. DQ2.5 refers to either a protein isoform and a genetic (chromosomal) haplotype. DQ2.5 isoform or heterodimer is shorthand for the cell...
    33 KB (3,380 words) - 17:14, 6 July 2024
  • Thumbnail for Tropomyosin
    much easier for an organism to expand on a current gene/protein family (creating protein isoforms) than it is to create an entirely new gene. From an evolutionary...
    51 KB (6,192 words) - 19:26, 10 May 2024
  • Thumbnail for G protein-coupled receptor
    for any single G-protein to deactivate if other factors did not come into play. Indeed, there are around 30 isoforms of RGS proteins that, when bound...
    82 KB (9,384 words) - 18:56, 11 June 2024
  • Thumbnail for Factor VIII
    Factor VIII (category Acute-phase proteins)
    large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple...
    17 KB (2,027 words) - 17:05, 10 May 2024
  • Thumbnail for Lipomatosis
    chromosome 12q15, where the HMGIC gene encodes the high-mobility-group protein isoform I-C. This is one of the most commonly found mutations in solitary lipomatous...
    4 KB (410 words) - 05:05, 5 April 2023
  • and most complete transcript of the gene, variant 1, encodes isoform 1 of the BEND2 protein (NP_699177.2). The untranslated regions (UTR) flanking the coding...
    22 KB (1,795 words) - 20:14, 20 September 2023
  • Thumbnail for FAM120AOS
    FAM120AOS (section Isoforms)
    protein, isoforms 1 and 2. The uncharacterized protein FAM120AOS isoform 1 is 256 amino acids long and the uncharacterized protein FAM120AOS isoform 2...
    37 KB (2,932 words) - 10:36, 13 June 2024
  • (a)PKCs (including protein kinase Mζ and ι / λ isoforms) require neither Ca2+ nor diacylglycerol for activation. The term "protein kinase C" usually refers...
    27 KB (2,650 words) - 21:16, 19 March 2024
  • Thumbnail for 5-HT2C receptor
    fully edited isoform, VGV, considerably reduces 5-HT potency, G-protein coupling and agonist binding, compared to the unedited protein isoform, INI. 72–76...
    51 KB (6,097 words) - 12:24, 28 June 2024
  • Thumbnail for CCDC121
    (CCDC121) is a protein encoded by the CCDC121 gene in humans. CCDC121 is located on the minus strand of chromosome 2 and encodes three protein isoforms. All isoforms...
    11 KB (1,166 words) - 02:41, 10 March 2024
  • Thumbnail for Major prion protein
    but occurs in many other tissues throughout the body. The protein can exist in multiple isoforms: the normal PrPC form, and the protease-resistant form designated...
    45 KB (5,229 words) - 20:07, 27 June 2024
  • Thumbnail for UBALD1
    UBALD1 (section Isoforms)
    isoform 1 encodes the longest protein that consists of 177 amino acids. The protein sequence from isoform 2 is 85.9% identical to isoform 1. Isoform 2...
    13 KB (1,174 words) - 15:42, 9 May 2024
  • Thumbnail for TEX9
    "testis-expressed protein 9 isoform 1 [Homo sapiens] - Protein - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2019-02-08. "TEX9 - Testis-expressed protein 9 - Homo sapiens...
    17 KB (1,202 words) - 00:06, 10 March 2024
  • Thumbnail for Western blot
    Western blot (category Protein methods)
    the potential to distinguish different protein isoforms, it may be used to diagnose prion and protein isoform-related diseases, such as cancer. For instance...
    66 KB (8,077 words) - 10:16, 9 July 2024
  • Thumbnail for ISLR
    ISLR (section Known isoforms)
    the longest protein isoform with the length of 2,331 bp, containing 2 exons. Transcript variant 2 encodes for the shorter protein isoform with the length...
    46 KB (4,000 words) - 02:01, 28 March 2024
  • of 3-ketosteroids into 3α-hydroxysteroids. The enzyme has various protein isoforms (isozymes). In humans, 3α-hydroxysteroid dehydrogenase is encoded by...
    16 KB (1,731 words) - 22:28, 12 May 2024
  • Thumbnail for Myotonin-protein kinase
    Ser/Thr protein kinase homologous to the MRCK p21-activated kinases and Rho kinase family. Data obtained by using antibodies that detect specific isoforms of...
    19 KB (2,426 words) - 16:47, 30 March 2024
  • C2orf74 (category Proteins)
    also known as LOC339804, is a protein encoding gene located on the short arm of chromosome 2 near position 15 (2p15). Isoform 1 of the gene is 19,713 base...
    22 KB (2,326 words) - 15:14, 29 April 2024
  • Protein folding, process by which a protein assumes its characteristic functional shape or tertiary structure Protein isoform, version of a protein with...
    5 KB (675 words) - 23:36, 15 September 2023
  • Thumbnail for AMP-activated protein kinase
    Carling D (May 1998). "Identification of a novel AMP-activated protein kinase beta subunit isoform that is highly expressed in skeletal muscle". The Journal...
    65 KB (7,147 words) - 05:41, 24 June 2024
  • Thumbnail for CGMP-dependent protein kinase
    structure of the cyclic GMP-dependent protein kinase I{beta} dimerization/docking domain reveals molecular details of isoform-specific anchoring". The Journal...
    8 KB (825 words) - 21:37, 20 April 2023
  • Thumbnail for TMEM101
    TMEM101 (section Isoforms)
    and 3. There are two known isoforms of the TMEM101 protein. Isoform a is encoded by transcript variant 1, while isoform b is encoded by transcript variants...
    20 KB (1,391 words) - 12:52, 18 August 2023
  • Thumbnail for C20orf27
    transcript variant 4. Transcript variant 1 encodes for the longest protein isoform, with a size of 1327 bases and 6 exons. Transcript variant 2 maintains...
    31 KB (3,092 words) - 01:49, 10 March 2024
  • Amelogenin (category Protein pages needing a picture)
    Amelogenins are a group of protein isoforms produced by alternative splicing or proteolysis from the AMELX gene, on the X chromosome, and also the AMELY...
    7 KB (857 words) - 10:36, 1 December 2023