Pyridoxal phosphate (PLP, pyridoxal 5'-phosphate, P5P), the active form of vitamin B6, is a coenzyme in a variety of enzymatic reactions. The International...
26 KB (2,937 words) - 11:06, 4 June 2024
Pyridoxal is one form of vitamin B6. Some medically relevant bacteria, such as those in the genera Granulicatella and Abiotrophia, require pyridoxal for...
4 KB (182 words) - 02:35, 20 March 2024
which can be interconverted in biological systems. Its active form, pyridoxal 5′-phosphate, serves as a coenzyme in more than 140 enzyme reactions in...
61 KB (6,987 words) - 08:57, 16 August 2024
In enzymology, a pyridoxal kinase (EC 2.7.1.35) is an enzyme that catalyzes the chemical reaction ATP + pyridoxal ⇌ {\displaystyle \rightleftharpoons }...
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enzyme pyridoxal phosphatase (EC 3.1.3.74) catalyzes the reaction pyridoxal 5′-phosphate + H2O ⇌ {\displaystyle \rightleftharpoons } pyridoxal + phosphate...
2 KB (197 words) - 15:37, 26 August 2023
In enzymology, a pyridoxal oxidase (EC 1.2.3.8) is an enzyme that catalyzes the chemical reaction pyridoxal + H2O + O2 ⇌ {\displaystyle \rightleftharpoons...
2 KB (148 words) - 15:37, 26 August 2023
be gained from the results of theoretical calculations. For example, pyridoxal phosphate, a form of vitamin B6, in aqueous solution is predicted to have...
10 KB (1,075 words) - 22:07, 3 June 2024
Pyridoxal 5′-phosphate synthase (glutamine hydrolysing) (EC 4.3.3.6, PdxST) is an enzyme with systematic name D-ribose 5-phosphate,D-glyceraldehyde 3-phosphate...
4 KB (447 words) - 15:37, 26 August 2023
In enzymology, a pyridoxal 4-dehydrogenase (EC 1.1.1.107) is an enzyme that catalyzes the chemical reaction pyridoxal + NAD+ ⇌ {\displaystyle \rightleftharpoons...
2 KB (129 words) - 15:37, 26 August 2023
Metafolin, a calcium salt of vitamin B9), methylcobalamin (vitamin B12) and pyridoxal 5'-phosphate (vitamin B6). It is a vitamin B supplement. Metanx is indicated...
3 KB (150 words) - 05:04, 2 March 2023
AspAT/ASAT/AAT or (serum) glutamic oxaloacetic transaminase (GOT, SGOT), is a pyridoxal phosphate (PLP)-dependent transaminase enzyme (EC 2.6.1.1) that was first...
19 KB (2,115 words) - 13:27, 22 July 2023
In molecular biology, group III pyridoxal-dependent decarboxylases are a family of bacterial enzymes comprising ornithine decarboxylase EC 4.1.1.17, lysine...
4 KB (358 words) - 10:17, 7 June 2021
It has been proposed that vitamin B6 in supplements should be in pyridoxal or pyridoxal phosphate form rather than pyridoxine as these are thought to reduce...
49 KB (4,453 words) - 11:41, 19 July 2024
four transsulfuration enzymes require vitamin B6 in its active form (pyridoxal phosphate or PLP). Three of these enzymes (cystathionine γ-synthase excluded)...
6 KB (831 words) - 23:19, 27 March 2024
niacin (vitamin B3) and the conversion of vitamin B6 to the coenzyme pyridoxal 5'-phosphate requires FMN. Riboflavin is involved in maintaining normal...
56 KB (5,567 words) - 14:05, 3 August 2024
six naturally occurring vitamers of vitamin B6 including pyridoxine, pyridoxal, and pyridoxamine as well as a 5'-phosphate derivative of each. All six...
12 KB (1,207 words) - 02:35, 12 March 2024
In molecular biology, the group I pyridoxal-dependent decarboxylases, also known as glycine cleavage system P-proteins, are a family of enzymes consisting...
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becomes an amino acid.[citation needed] Transaminases require the coenzyme pyridoxal phosphate, which is converted into pyridoxamine in the first half-reaction...
8 KB (784 words) - 21:00, 13 April 2024
or proteolipid protein 2, associated with Pelizaeus-Merzbacher disease Pyridoxal phosphate, a coenzyme, the active form of vitamin B6 Packet Layer Protocol...
1 KB (209 words) - 15:01, 7 July 2024
pyruvate + L-glutamate ALT (and all aminotransferases) require the coenzyme pyridoxal phosphate, which is converted into pyridoxamine in the first phase of...
13 KB (1,373 words) - 03:13, 5 August 2024
organic prosthetic groups are vitamin derivatives: thiamine pyrophosphate, pyridoxal-phosphate and biotin. Since prosthetic groups are often vitamins or made...
8 KB (817 words) - 03:17, 14 August 2024
(5-HTP). Subsequently, 5-HTP undergoes decarboxylation, facilitated by pyridoxal phosphate and the enzyme 5-hydroxytryptophan decarboxylase, yielding serotonin...
66 KB (7,076 words) - 02:57, 12 August 2024
B3 (niacin) Vitamin B5 (pantothenic acid) Vitamin B6 group: Pyridoxine Pyridoxal-5-Phosphate Pyridoxamine Vitamin B7 (biotin) Vitamin B9 (folate) Vitamin...
5 KB (381 words) - 04:59, 1 April 2024
mechanistic features with other pyridoxal- phosphate dependent enzymes, such as the covalent binding of the pyridoxal- phosphate group to a lysine residue...
3 KB (168 words) - 17:24, 12 May 2024
In molecular biology, group IV pyridoxal-dependent decarboxylases are a family of enzymes comprising ornithine decarboxylase EC 4.1.1.17, lysine decarboxylase...
4 KB (315 words) - 00:02, 3 January 2021
sideroblastic anemia SLC25A38 206000 pyridoxine-responsive sideroblastic anemia (vitamin B6 deficiency; pyridoxal phosphate required for heme synthesis)...
16 KB (1,724 words) - 04:51, 18 August 2024
synthesized from glutamate via the enzyme glutamate decarboxylase (GAD) with pyridoxal phosphate (the active form of vitamin B6) as a cofactor. This process...
51 KB (5,494 words) - 04:45, 10 August 2024
Chloroquine EGCG GTP GW5074 Hexachlorophene Hydroxylamine Palmitoyl-CoA Pyridoxal phosphate GSTooltip Glutamine synthetase 2-Aminoadipic acid JFD01307SC...
22 KB (2,092 words) - 15:05, 23 July 2024
In molecular biology, group II pyridoxal-dependent decarboxylases are family of enzymes including aromatic-L-amino-acid decarboxylase (L-dopa decarboxylase...
3 KB (255 words) - 23:42, 25 January 2023
Chloroquine EGCG GTP GW5074 Hexachlorophene Hydroxylamine Palmitoyl-CoA Pyridoxal phosphate GSTooltip Glutamine synthetase 2-Aminoadipic acid JFD01307SC...
37 KB (3,650 words) - 17:39, 27 July 2024