The renal outer medullary potassium channel (ROMK) is an ATP-dependent potassium channel (Kir1.1) that transports potassium out of cells. It plays an important...

1 SLC12A1 (NKCC2) Na-K-2Cl symporter neonatal Bartter's syndrome type 2 ROMK/KCNJ1 thick ascending limb K+ channel classic Bartter's syndrome type 3 CLCNKB...

H; Syn, S; Palmer, L G; Choe, H; Walters, D E (Feb 2001). "Regulation of ROMK by extracellular cations". Biophysical Journal. 80 (2): 683–697. Bibcode:2001BpJ...

Hypomagnesemia also causes activation of the Renal outer medullary potassium channel (ROMK), a potassium channel which causes potassium losses in the urine via the...

upregulatory effects on ROMK channels. miR-802 thus functions to mediate the stimulatory effect of a high potassium diet on ROMK activity through suppression...

apical epithelial sodium channels, ENaC, as well as potassium channels, ROMK. These actions increase sodium reabsorption and potassium secretion. Since...

generating the electrochemical gradient necessary for potassium efflux by ROMK channel). Treatment of severe forms of PHA1 requires relatively large amounts...

H, Syn S, Palmer LG, Choe H, Walters DE (February 2001). "Regulation of ROMK by extracellular cations". Biophysical Journal. 80 (2): 683–697. Bibcode:2001BpJ...

membrane expression of the inward rectifier ATP-dependent potassium channel ROMK. Klotho-deficient mice show increased production of vitamin D, and altered...

potassium excretion via the sodium-potassium exchange mechanism (i.e. apical ROMK/Na channels coupled with basolateral Na+/K ATPases). This can result in a...

increase the activity of the basolateral Na/K ATPase, ENaC sodium channels and ROMK potassium channels of the principal cell in the distal tubule and cortical...

potential with loss of parasympathetic control, resulting in a faster heart rate ROMK is found in the kidneys where it contributes to K+ recycling. An inhibition...

Nimesulide Rottlerin (mallotoxin) Tolfenamic acid Inwardly rectifying 2T & 1P ROMK (Kir1.1) [citation needed] none GPCR regulated (Kir3.x) [citation needed]...

Garty H, Palmer LG, Popovtzer MM (Aug 1998). "Differential regulation of ROMK expression in kidney cortex and medulla by aldosterone and potassium". The...

and gene expression. Therefore, the production and expression of ENaC and ROMK electrolyte channels in the distal nephrons, which give the drug its diuretic...

Pseudopeptidoglycan Pseudopodia Pterygium Q-type calcium channel R-type calcium channel ROMK RYR1 RYR3 Radial spoke Receptor (biochemistry) Reinhart Heinrich Reversal...

epithelial Na+ channel (ENaC), renal outer medullary potassium channel (ROMK), transient receptor potential vanilloid member 4 and 5 (TRPV4/5, calcium...

Plasma: ↑renin, ↓K, ↑CO2, mild ↓Mg in some patients; Urine: ↑Ca [601678] ROMK (type 2) 11q24 AR [241200] C1C-Kb (type 3, classic) 1p36 AR [607364] 1p31...

TP, Olsen O, et al. (2004). "Assembly and trafficking of a multiprotein ROMK (Kir 1.1) channel complex by PDZ interactions". J. Biol. Chem. 279 (8): 6863–73...

up-regulated by a low K intake and suppresses renal outer medullary K channels (ROMK) by MAPK stimulation". Proceedings of the National Academy of Sciences of...