RTI-7470-44 is a potent and selective antagonist of the human trace amine-associated receptor 1 (TAAR1) which is used in scientific research. It was discovered...
8 KB (797 words) - 08:41, 9 September 2024
of the hTAAR1 antagonist RTI-7470-44, endowed with a species-specificity preference over mTAAR1 (Figure 11A) [99]. RTI-7470-44 displayed good blood–brain...
59 KB (6,807 words) - 21:42, 17 August 2024
Agonists Neutral antagonists RTI-7470-44 Inverse agonists EPPTB (RO5212773)...
46 KB (4,510 words) - 12:55, 16 October 2024
which as discussed above is associated with a markedly elevated PE turnover [44]. Further, amphetamines, which have clinical utility in ADHD, are good ligands...
20 KB (2,302 words) - 05:17, 18 August 2024
Agonists Neutral antagonists RTI-7470-44 Inverse agonists EPPTB (RO5212773)...
14 KB (1,633 words) - 08:11, 1 September 2024
the effects of these drugs appear to be mediated by TAAR1 agonism. RTI-7470-44 Bradaia A, Trube G, Stalder H, Norcross RD, Ozmen L, Wettstein JG, et al...
7 KB (652 words) - 18:55, 20 August 2024
Agonists Neutral antagonists RTI-7470-44 Inverse agonists EPPTB (RO5212773)...
32 KB (2,036 words) - 11:13, 25 February 2024
Agonists Neutral antagonists RTI-7470-44 Inverse agonists EPPTB (RO5212773)...
8 KB (928 words) - 07:45, 8 October 2024
Agonists Neutral antagonists RTI-7470-44 Inverse agonists EPPTB (RO5212773)...
9 KB (946 words) - 19:05, 15 August 2024