Ryanodine receptor 2 (redirect from RyR2)
receptor 2 (RYR2) is one of a class of ryanodine receptors and a protein found primarily in cardiac muscle. In humans, it is encoded by the RYR2 gene. In...
16 KB (1,771 words) - 06:12, 25 September 2024
calcium within cardiac muscle cells. The most commonly identified gene is RYR2, which encodes a protein included in an ion channel known as the ryanodine...
42 KB (4,764 words) - 15:55, 4 January 2024
signaling pathways involving calcium release from intracellular organelles. The RYR2 ryanodine receptor isoform is the major cellular mediator of calcium-induced...
21 KB (2,355 words) - 13:40, 24 June 2024
gertschi. Hadrucalcin modifies the Ryanodine receptor channels RyR1 and RyR2, found in the sarcoplasmic reticulum, to a long-lasting subconductance state...
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of cardiac myocytes by binding to and stabilizing the ryanodine receptor (RyR2) in its closed state. It can be used in the treatment of cardiac arrhythmias...
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There are three types of ryanodine receptor, RyR1 (in skeletal muscle), RyR2 (in cardiac muscle) and RyR3 (in the brain). Calcium release through ryanodine...
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break a tachyarrhythmia. Flecainide also inhibits ryanodine receptor 2 (RyR2), a major regulator of sarcoplasmic release of stored calcium ions. It can...
25 KB (2,632 words) - 13:08, 23 March 2024
to physically link the RYR2 and CASQ2 proteins, so that RYR2 channel activity can be regulated by CASQ2. The linkage of RYR2 with CASQ2 occurs via highly...
18 KB (1,884 words) - 17:56, 31 January 2024
Xie W, Reiken S, D'Ascia SL, et al. (May 2015). "Calcium release channel RyR2 regulates insulin release and glucose homeostasis". The Journal of Clinical...
166 KB (18,358 words) - 23:39, 24 August 2024
Xie W, Reiken S, D'Ascia SL, et al. (May 2015). "Calcium release channel RyR2 regulates insulin release and glucose homeostasis". The Journal of Clinical...
121 KB (13,799 words) - 18:31, 13 September 2024
release from the sarcoplasmic reticulum by activating ryanodine receptor 2 (RyR2) (calcium-induced-calcium-release). Phosphorylation of these channels increases...
17 KB (2,004 words) - 01:57, 7 August 2024
many proteins. These include mammalian ion channels (CatSper1, TASK, RyR1, RyR2, RyR3, TRPM6, TRPM8, TRPV1, TRPV2, TRPV3, TRPV4, TRPV5, TRPV6, TRPA1, mCa1...
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resistance and results from a missense variant of the type 2 ryanodine receptor (RyR2) gene (p.N2291D). In lean subjects it is significantly higher than in a population...
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rhythm of the muscle. Another study was done for molecular autopsy on the RyR2-encoded cardiac ryanodine receptor in SUDS. There were 49 cases in this study...
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Type OMIM Gene Locus Reference ARVD1lpl 107970 TGFB3 14q23-q24 ARVD2 600996 RYR2 1q42-q43 ARVD3 602086 ? 14q12-q22 ARVD4 602087 ? 2q32.1-q32.3 ARVD5 604400...
50 KB (5,441 words) - 04:00, 19 August 2024
antagonist and a voltage-independent activator of the ryanodine receptors (RYR1, RYR2, and RYR3). It is also a competitive antagonist of the ionotropic glycine...
202 KB (20,197 words) - 02:19, 22 September 2024
withstand the low oxygen level at high elevations. It has a strong selection for RYR2, a gene that initiates cardiac excitation. The mitochondrial DNA of 27 wolves...
56 KB (5,583 words) - 12:59, 5 October 2024
binds to and activates another receptor, called a type 2 ryanodine receptor (RyR2), located on the membrane of a structure known as the sarcoplasmic reticulum...
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increased intracellular calcium (Calcium Induced Calcium Release - CICR) RYR1, RYR2, RYR3 ER/SR Calcium-induced calcium release in myocytes Two-pore channel...
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muscle, while the L-type calcium channel (DHPR on cardiac myocytes) and RyR2 (main RyR isoform in cardiac muscle) are not physically coupled in cardiac...
62 KB (7,395 words) - 14:24, 5 October 2024
Xie W, Reiken S, D'Ascia SL, et al. (May 2015). "Calcium release channel RyR2 regulates insulin release and glucose homeostasis". The Journal of Clinical...
32 KB (3,743 words) - 19:49, 22 May 2024
CACNA1G; CACNA1H; CACNA1I; CACNA1S CATSPER1; CATSPER2; CATSPER3; CATSPER4 RYR1; RYR2; RYR3 Kvα1.x - Shaker-related: Kv1.1 (KCNA1), Kv1.2 (KCNA2), Kv1.3 (KCNA3)...
19 KB (1,692 words) - 03:53, 29 November 2023
RASGRP3; RCN1; RCN2; RCN3; RCV1; RCVRN; REPS1; RHBDL3; RHOT1; RHOT2; RPTN; RYR2; RYR3 S100A1; S100A11; S100A12; S100A6; S100A8; S100A9; S100B; S100G; S100Z;...
17 KB (2,077 words) - 16:17, 5 September 2024
resistance and results from a missense variant of the type 2 ryanodine receptor (RyR2) gene (p.N2291D). In several populations, SPINA-GBeta correlated with the...
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group from CXL 1020 interacts with ryanodine receptors (RyR), specifically RyR2, which is the predominant form found in cardiac tissue. Ryanodine receptors...
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yamamoto m, mcghee jr, elson co, et al. J immunol. 1995 jun 1;154(11):5611-9. RYR2 sequencing reveals novel missense mutations in a Kazakh idiopathic ventricular...
12 KB (1,390 words) - 04:20, 19 July 2024
biophysical properties of TRIC-A and TRIC-B and their interactions with RyR2 Santoor maestro Pandit Bhajan Sopori passes away La Follette's favorite son...
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HGNC:10480 Q8N488 14207 RYK HGNC:10481 P34925 14208 RYR1 HGNC:10483 P21817 14209 RYR2 HGNC:10484 Q92736 14210 RYR3 HGNC:10485 Q15413 14211 S1PR1 HGNC:3165 P21453...
282 KB (17 words) - 18:42, 6 October 2024
sarcoplasmic reticulum calcium release channel, and the ryanodine receptor 2 (RyR2). CALM1 disease mutations are often diagnosed in patients aged ten or younger...
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interactions including 8 co-complex interactions. PLCE1 appears to interact with RyR2, HRAS, NRAS, and LIMS1. GRCh38: Ensembl release 89: ENSG00000138193 – Ensembl...
15 KB (1,740 words) - 06:00, 24 December 2023