RhoGEF domain describes two distinct structural domains with guanine nucleotide exchange factor (GEF) activity to regulate small GTPases in the Rho family...
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FYVE, RhoGEF and PH domain containing (FGD) is a gene family consisting of: FGD1 FGD2 FGD3 FGD4 Type 1 is associated with Aarskog-Scott syndrome. Guanine...
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involved in Rho family GTPase signaling (see Rho family of GTPases). This is through the RhoGEF superfamily involving the RhoGEF domain of the proteins'...
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homology and RhoGEF domain containing G3 is a protein that in humans is encoded by the PLEKHG3 gene. Pleckstrin homology domain RhoGEF domain GRCh38: Ensembl...
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PMID 16001362. "Entrez Gene: PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4". Flanigan K, Gardner K, Alderson K, et al...
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FERM, RhoGEF and pleckstrin domain-containing protein 1 is a protein that in humans is encoded by the FARP1 gene. This gene was originally isolated through...
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ARHGEF1 (redirect from P115 RhoGEF)
or p115-RhoGEF. Rho guanine nucleotide exchange factor 1 is guanine nucleotide exchange factor (GEF) for the RhoA small GTPase protein. Rho is a small...
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Functional generative description, a linguistic framework FYVE, RhoGEF and PH domain containing This disambiguation page lists articles associated with...
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ARHGEF6 (section Domains and functions)
contains a central DH/PH RhoGEF domain that functions as a guanine nucleotide exchange factor (GEF) for small GTPases of the Rho family, and specifically...
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PH domain is also present in other proteins beyond RhoGEFs. The DHR2 domain is the catalytic domain of the DOCK family of Rho GEFs. Like DH domain, DHR2...
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T (January 2003). "Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF". Proceedings of the National Academy of...
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ARHGEF7 (section Domains and functions)
contains a central DH/PH RhoGEF domain that functions as a guanine nucleotide exchange factor (GEF) for small GTPases of the Rho family, and specifically...
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Library of Medicine. "Entrez Gene: Pleckstrin homology domain containing, family G (with RhoGef domain) member 5". Dachsel JC, Ngok SP, Lewis-Tuffin LJ, Kourtidis...
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FERM, RhoGEF and pleckstrin domain-containing protein 2 is a protein that in humans is encoded by the FARP2 gene. FARP2 has been shown to interact with...
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Fort P, Blangy A (June 2017). "The Evolutionary Landscape of Dbl-Like RhoGEF Families: Adapting Eukaryotic Cells to Environmental Signals". Genome Biol...
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RhoGEF11 or PDZ-RhoGEF. Rho guanine nucleotide exchange factor 11 is guanine nucleotide exchange factor (GEF) for the RhoA small GTPase protein. Rho is a small...
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the Rho family Small GTPase (RhoGTPase) to GTP, and PLEKHG2 having this domain also acts as a Rho-specific guanine nucleotide exchange factor (RhoGEF)....
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FYVE, RhoGEF and PH domain-containing protein 4 is a protein encoded in humans by the FGD4 gene. FYVE, RhoGEF and PH domain containing FYVE domain (zinc...
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Ig domains, 2 fibronectin domains, 1 IQ calmodulin-binding motif, 1 RhoGEF domain with an associated PH domain, and 2 serine-threonine kinase domains. The...
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FYVE may refer to: FYVE domain FYVE finger-containing phosphoinositide kinase FYVE, RhoGEF and PH domain containing This disambiguation page lists articles...
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contain a RhoGEF domain to function as guanine nucleotide exchange factors to promote GDP release and GTP binding to specific Small GTPases of the Rho family...
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protein that in humans is encoded by the ABR gene. The ABR activator of RhoGEF and GTPase, also symbolized as ABR, gene has a reported 13 alternatively...
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RhoGEF and PH domain-containing protein 3 is a protein that in humans is encoded by the FGD3 gene. FYVE, RhoGEF and PH domain containing FYVE domain (zinc...
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GTPase (section G domain GTPases)
complex). Upon receptor activation, the activated receptor intracellular domain acts as GEF to release GDP from the G protein complex and to promote binding of...
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FYVE, RhoGEF and PH domain-containing protein 2 (FGD2), also known as zinc finger FYVE domain-containing protein 4 (ZFYVE4), is a protein that in humans...
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pellino homolog 2 PLEKHG3: encoding protein Pleckstrin homology and rhogef domain containing g3 PSEN1: presenilin 1 (Alzheimer disease 3) RIOX1: encoding...
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cell. RhoC expression has been associated with several signaling pathways and effectors. Here is a list of the ones found so far: IQGAP1 (IQ-domain GTP-ase...
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factor receptors (FGFR) FH2 protein (formin) gene family FGD (FYVE, RhoGEF and PH domain containing) family Heat shock proteins Heat shock factor Ion channels...
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The TBC domain is an evolutionarily conserved protein domain found in all eukaryotes. It is approximately 180 to 200 amino acids long. The domain is named...
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DBL-homology (DH) domain), so DBL is also named as a member of this RhoGEF family as ARHGEF21. DH domains function to activate small GTPases of the Rho family by...
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