Lynn Dalgarno (born 12 November 1935) is an Australian geneticist known for the discovery of the Shine–Dalgarno sequence with his graduate student, John...
13 KB (1,307 words) - 11:58, 22 October 2024
the Shine-Dalgarno (SD) sequence in mRNA for bacteria. The SD sequence is located near the start codon which is in contrast to the Kozak sequence which...
30 KB (3,629 words) - 19:23, 6 December 2024
5'-AGGAGG-3', also called the Shine-Dalgarno (SD) sequence. The complementary sequence (CCUCCU), called the anti-Shine-Dalgarno (ASD) is contained in the...
12 KB (1,334 words) - 18:34, 13 December 2024
subunit of a prokaryotic ribosome (SSU rRNA). It binds to the Shine-Dalgarno sequence and provides most of the SSU structure. The genes coding for it...
34 KB (3,792 words) - 16:31, 29 November 2024
operator. It also specifies a Shine–Dalgarno sequence flanked by two unique restriction sites (portable Shine–Dalgarno sequence). The tacI and the tacII promoters...
6 KB (820 words) - 18:45, 17 August 2023
The majority of mRNAs in E. coli are prefaced with a Shine-Dalgarno (SD) sequence. The SD sequence is recognized by an complementary "anti-SD" region on...
23 KB (2,926 words) - 04:10, 2 November 2024
length. The 5' UTR of prokaryotes consists of the Shine–Dalgarno sequence (5'-AGGAGGU-3'). This sequence is found 3-10 base pairs upstream from the initiation...
12 KB (1,454 words) - 11:42, 20 October 2024
suggest that Mu-gpT-DE RNAs are found in phages and prophages. Some Mu-gpT-DE RNAs contain a stem that overlaps the Shine-Dalgarno sequence of the downstream...
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highly conserved uridine nucleotides found directly opposite the Shine-Dalgarno sequence on hairpin II (pictured). RNA thermometers such as FourU control...
12 KB (1,229 words) - 05:30, 8 November 2023
the Shine-Dalgarno (SD) sequence in mRNA. PreQ1 mediated inhibition of translational regulation is controlled by blocking the Shine-Dalgarno sequence of...
19 KB (2,058 words) - 23:58, 30 June 2024
Toxic Small RNA (section Sequence and structure)
has been studied. It contains a conserved sequence that is the reverse complement of the Shine-Dalgarno sequence of many transport and metabolic transcripts...
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Ribosome (category CS1 German-language sources (de))
ribosome first. The ribosome recognizes the start codon by using the Shine-Dalgarno sequence of the mRNA in prokaryotes and Kozak box in eukaryotes. Although...
65 KB (7,283 words) - 04:25, 1 January 2025
alone is not sufficient to begin the process. Nearby sequences such as the Shine-Dalgarno sequence in E. coli and initiation factors are also required...
73 KB (8,046 words) - 18:12, 31 December 2024
(3): 267–273. doi:10.1007/s11262-019-01641-7. PMC 7088766. PMID 30796742. de la Parra C, Walters BA, Geter P, Schneider RJ (February 2018). "Translation...
12 KB (1,418 words) - 09:36, 5 December 2024
Non-coding RNA (redirect from Untranslated sequence)
bacterial ncRNA, OxyS RNA represses translation by binding to Shine-Dalgarno sequences thereby occluding ribosome binding. OxyS RNA is induced in response...
67 KB (7,178 words) - 04:34, 29 October 2024
supervision of Dr Ken Reed and Dr Lynn Dalgarno (who along with Dr John Shine uncovered the Shine-Dalgarno sequence). She earned a PhD (1982) in Biochemistry...
10 KB (1,092 words) - 02:37, 19 November 2024
ribosomal RNA (in a ribosome) recognizes a sequence on the 5' end of mRNA called the Shine-Dalgarno sequence. In contrast, eukaryotes generally have many...
60 KB (7,203 words) - 11:15, 18 November 2024
sequence of the mRNA, the Shine-Dalgarno sequence, and the corresponding recognition sequence in the 16S rRNA of ribosomes, the so-called Anti-Shine-Dalgarno-Sequence...
79 KB (9,132 words) - 16:16, 17 November 2024
cis-regulatory region of ncRNA in the 5' UTR of cspA presents the Shine-Dalgarno sequence and AUG start codon to the ribosome in a more accessible way. The...
5 KB (558 words) - 07:02, 26 August 2021
6 nt (median distance) upstream of start codons as the consensus Shine–Dalgarno sequence in H. pylori. The proteome of H. pylori has been systematically...
148 KB (16,654 words) - 05:08, 30 December 2024
genes on the mRNA strand has its own Shine-Dalgarno sequence, so the genes are independently translated. The DNA sequence of the E. coli lac operon, the lacZYA...
40 KB (5,255 words) - 06:14, 21 December 2024
because it encounters a highly conserved sequence (a Kozak consensus sequence in eukaryotes, or Shine-Dalgarno sequence in prokaryotes). The stalled complex...
11 KB (1,164 words) - 20:49, 20 October 2023
bears eukaryote-like intron sequences. The Shine-Dalgarno sequence GAGG dominates in virus T4 early genes, whereas the sequence GGAG is a target for the...
43 KB (5,371 words) - 18:28, 12 June 2024
ROSE elements contain a characteristic 'bulged G' opposite the Shine-Dalgarno sequence binding site, without this nucleotide the RNA thermometer loses...
6 KB (580 words) - 11:17, 18 August 2023
host. For example, prokaryotes expression vectors would have a Shine-Dalgarno sequence at its translation initiation site for the binding of ribosomes...
34 KB (4,182 words) - 17:22, 7 December 2024
synthesis at the UAG stop codon, as long as it is preceded by a strong Shine-Dalgarno sequence. At initiation it not only inserts the traditional formylmethionine...
67 KB (8,010 words) - 00:05, 30 November 2024
TSS cases. In the nucleotide sequence of TSST-1, there is a 708 base-pair open-reading frame and a Shine-Dalgarno sequence which is seven base pairs downstream...
18 KB (2,409 words) - 08:53, 28 September 2024
mRNA and begins translation. In prokaryotes, the RBS includes a Shine-Dalgarno sequence. Little is known about the translation efficiency of RBSs in Synechocystis...
31 KB (3,536 words) - 19:43, 17 September 2024
(Hld). RNAIII contains many stem loops, most of which match the Shine-Dalgarno sequence involved in translation initiation of the regulated genes. Some...
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respectively. Alternatively, riboswitches may bind or occlude the Shine–Dalgarno sequence, affecting translation. It has been suggested that these originated...
92 KB (10,711 words) - 00:40, 17 December 2024