Paired amphipathic helix protein Sin3a is a protein that in humans is encoded by the SIN3A gene. The protein encoded by this gene is a transcriptional...

function of switch‐insensitive 3 transcription regulator family member A (SIN3A). The syndrome was discovered by developmental neuroscientists Josefine...

Sin3A-associated protein, 30kDa, also known as SAP30, is a protein which in humans is encoded by the SAP30 gene. Histone acetylation plays a key role...

syndrome with or without renal agenesis Noonan syndrome 4 Orofacial cleft 15 SIN3A-related intellectual disability syndrome due to a point mutation Singleton-Merten...

Renpenning syndrome Seckel syndrome 9 Severe X-linked myotubular myopathy SIN3A-related intellectual disability syndrome due to a point mutation...

Density 95 RASA1 (RasGAP) Not known Ras GTPase activating protein SH3GL3 Yes Endocytosis SIN3A Yes Transcriptional repressor Sp1 Yes Transcription factor...

RCOR (REST corepressor) RCOR1 (RCOR1) RCOR2 (RCOR2) RCOR3 (RCOR3) Sin3 SIN3A (SIN3A) SIN3B (SIN3B) TIF1 (transcriptional intermediary factor 1) TRIM24 Tripartite...

Witteveen-Kolk syndrome is a rare genetic disorder caused by mutation on the SIN3A gene in the long arm of chromosome 15 This disambiguation page lists articles...

inhibition of the tumor suppressor p53 which then leads to enhanced oncogenesis. SIN3A, a regulator of MYC, that acts to inhibit MYC by deacetylating it, is often...

to interact with: GATAD2B, HDAC1, Histone deacetylase 2, MBD3 MIZF, and SIN3A. GRCh38: Ensembl release 89: ENSG00000134046 – Ensembl, May 2017 GRCm38:...

methylated CpG sites on the DNA strands. The TRD region then reacts with SIN3A to recruit histone deacetylases (HDAC). There are also unusual, repetitive...

SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003).[supplied by OMIM] SAP130 has been shown to interact with: CSN1S1, CUL2, Myc, SIN3A,...

357–64. doi:10.1016/S0092-8674(00)80216-0. PMID 9150135. "Entrez Gene: SAP18 Sin3A-associated protein, 18kDa". Michelle L, Cloutier A, Toutant J, Shkreta L...

and 5) in ~40% of cases one or more of various other genes such as MLL2, SIN3A, ARID1A, EP300, CREBBP, and TBL1XR1) that have chromatin remodeling activity...

P81133 14799 SIM2 HGNC:10883 Q14190 14800 SIMC1 HGNC:24779 Q8NDZ2 14801 SIN3A HGNC:19353 Q96ST3 14802 SIN3B HGNC:19354 O75182 14803 SINHCAF HGNC:30702...

gene and contain binding sites for transcription factors RCOR1, MILLT1, SIN3A, NFIC, STAT3, JUNB, FOS, EGR1, PHB2, RUNX3, and SRF. Many of these transcription...

These complexes include Sin3 (named after its characteristic protein mSin3A), Nucleosome Remodelling and Deacetylating complex (NuRD), and Co-REST....

CREBBP, CCNE1, ESR1, FANCA, HSP90B1, ING1, Myc, NR3C1, P53, POLR2A, PHB, SIN3A, SMARCB1, SMARCC1, SMARCC2, SMARCE1, STAT2, and STK11. GRCh38: Ensembl release...

been shown to interact with: ACTL6A, ARID1B, CEBPB, POLR2A, Prohibitin, SIN3A, SMARCB1, SMARCC1, and SS18. - Nicolaides Baraitser Syndrome (NCBRS) GRCh38:...

a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003).[supplied by OMIM]...

humans is encoded by the PHF12 gene. PHF12 has been shown to interact with SIN3A. GRCh38: Ensembl release 89: ENSG00000109118 – Ensembl, May 2017 GRCm38:...

a co-repressor complex to promote histone deacetylation upon binding to SIN3A. SUMOylation refers to the addition of Small Ubiquitin-like Modifier (SUMO)...

DePinho RA, Dejean A (May 1998). "Histone deacetylase associated with mSin3A mediates repression by the acute promyelocytic leukemia-associated PLZF...

(April 2001). "PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors". Molecular and...

Retinoblastoma-like protein 1, Retinoblastoma-like protein 2, SAP30, SATB1, SIN3A, SIN3B, SPEN, SUDS3, SUV39H1, Sp1 transcription factor, TOP2A, TOP2B, and...

with: BAP1, CREB3, GABPA, HDAC1, HDAC2, MLL, OGT, PDCD2, POU2F1, PPP1CA, SIN3A, SP1, SUDS3, WDR5, and ZBTB17. GRCh38: Ensembl release 89: ENSG00000172534...

to interact with NFKB1, RELA, RELB, BTRC, RPS27A, BCL3, MAP3K8, NFKBIA, SIN3A, SUMO1, Tat. Mutations in the TANGO2 gene may cause defects in mitochondrial...

activity via interaction with the common transcriptional co-repressor, Sin3A. KLFs 15 and 17 are distantly related without any defined protein interaction...

Histone H2B, AKT1, PFKL, KMT2E/MLL5, MAPT/TAU, Host cell factor C1, and SIN3A. O-GlcNAc transferase is a part of a host of biological functions within...

The encoded protein is a subunit of the histone deacetylase-dependent SIN3A transcriptional corepressor complex, which functions in diverse cellular...