Suppressor of cytokine signaling 2 is a protein that in humans is encoded by the SOCS2 gene. This gene encodes a member of the STAT-induced STAT inhibitor (SSI)...
10 KB (1,147 words) - 09:55, 4 January 2024
family: cytokine-inducible SH2 domain-containing protein (CISH), SOCS1, SOCS2, SOCS3, SOCS4, SOCS5, SOCS6, and SOCS7, each protein has an SH2 domain and...
62 KB (6,845 words) - 18:30, 22 August 2024
SH2D5; SH2D6; SH3BP2; SHB; SHC1; SHC3; SHC4; SHD; SHE SLA; SLA2 SOCS1; SOCS2; SOCS3; SOCS4; SOCS5; SOCS6; SOCS7 SRC; SRMS STAT1; STAT2; STAT3; STAT4;...
13 KB (1,341 words) - 04:09, 6 March 2024
O75908 15481 SOBP HGNC:29256 A7XYQ1 15482 SOCS1 HGNC:19383 O15524 15483 SOCS2 HGNC:19382 O14508 15484 SOCS3 HGNC:19391 O14543 15485 SOCS4 HGNC:19392 Q8WXH5...
242 KB (17 words) - 23:17, 27 April 2024
genes involved in inhibiting the JAK-STAT signaling pathway. CISH SOCS1 SOCS2 SOCS3 SOCS4 SOCS5 SOCS6 SOCS7 All SOCS have certain structures in common...
3 KB (396 words) - 07:09, 22 August 2024
which are involved primarily in xenobiotic metabolism. These genes include SOCS2 (i.e. suppressor of cytokine signaling 2), CYP1A1, CYP1A2, CYP1B1, glutathione...
37 KB (4,357 words) - 04:19, 25 March 2024
Tolerogenic nanoparticles inhibit T cell-mediated autoimmunity through SOCS2. Science signaling, 9(433), ra61 (2016). 14. Rothhammer, V., Mascanfroni...
18 KB (2,559 words) - 12:54, 18 March 2024
"IL-10 attenuates IFN-alpha-activated STAT1 in the liver: involvement of SOCS2 and SOCS3". FEBS Lett. 480 (2–3): 132–6. doi:10.1016/S0014-5793(00)01905-0...
16 KB (1,922 words) - 21:02, 8 November 2023
interact with: CRKL, Erythropoietin, Grb2, Janus kinase 2, LYN, PIK3R1, PTPN6, SOCS2, SOCS3, and STAT5A. GRCh38: Ensembl release 89: ENSG00000187266 – Ensembl...
28 KB (3,409 words) - 18:05, 8 June 2024
differentiation through activation of the JAK2-STAT3 pathway via degradation of SOCS2. Furthermore, reduction of ATG5 levels in mice brains leads to a suppression...
22 KB (2,808 words) - 09:48, 15 April 2024
GRB10, IRS1, Mdm2, NEDD4, PIK3R3, PTPN11, RAS p21 protein activator 1, SHC1 SOCS2, SOCS3, and YWHAE. There is evidence to suggest that IGF1R is negatively...
29 KB (3,603 words) - 16:26, 25 May 2024
(October 1999). "Radiation hybrid and cytogenetic mapping of SOCS1 and SOCS2 to chromosomes 16p13 and 12q, respectively". Genomics. 61 (1): 108–11. doi:10...
16 KB (1,957 words) - 06:54, 14 July 2024