Transcription factor SOX-10 is a protein that in humans is encoded by the SOX10 gene. This gene encodes a member of the SOX (SRY-related HMG-box) family...

in SOX10 (the same gene as in type 2E), in which it is known as type 4C; hearing loss is very common and severe in this type. A mutation in SOX10, the...

In the absence of SOX10, neural crest cells survive and are free to generate neurons, but glial specification is blocked. SOX10 might influence early...

movement and coordination. Research in mice has shown that a mutation in SOX10, an SRY encoded transcription factor, is linked to the condition of Dominant...

Immunohistochemistry with SOX10 (staining the cell nuclei of melanocytes) of lentigo maligna, showing malignant melanocytes all the way to the resection...

diagnosing uncertain cases Metastatic melanoma on immunohistochemistry for SOX10, another helpful stain in uncertain cases One method is the "ugly duckling...

border specifiers is a collection of genes including Slug/Snail, FoxD3, Sox10, Sox9, AP-2 and c-Myc. This suite of genes, designated here as neural crest...

HSCR7 606875 ? 19q12 HSCR8 608462 ? 16q23 HSCR9 611644 ? 4q31-32 — 602229 SOX10 22q13 — 600423 ECE1 1p36.1 — 602018 NRTN 19p13.3 — 602595 GEMIN2 (Gem-associated...

KAL1, fibroblast growth factor (FGF8), sex determining region Y-Box 10 (SOX10), GNRHR, GNRH1 and KISS1R. Kallmann syndrome results in a loss of smell...

characteristic atypical epidermal melanocytes. H&E stain. Immunohistochemistry with SOX10 (staining the cell nuclei of melanocytes) facilitates diagnosis of lentigo...

condition caused by a mutation on the SRY-related HMG-box gene 10 (not SOX10). It was characterized in 1990, after being seen in two siblings from Yemen...

has shown that SOX10 (a neuroectodermal master modulator) and MYC (an oncogene) are the major regulators. Rab7a is regulated by SOX10 and MYC respectively...

homolog SEPT3: encoding protein neuronal-specific septin-3 SEPT5 SHFM3P1: SOX10 SYNGR1: encoding protein synaptogyrin-1 TBC1D10A: encoding protein TBC1...

Known motif – from protein with 100% identical DBD – in vitro [841] WBAAW SOX10 ENSG00000100146 HMG/Sox Known motif – High-throughput in vitro [842] DAACAWWGVV...

1:10,000 Waardenburg syndrome PAX3, MITF, WS2B, WS2C, SNAI2, EDNRB, EDN3, SOX10 dominant 1:42,000 Warkany syndrome 2 8 trisomy Weissenbacher–Zweymüller...

MODY 3 MODY 5 SF1 SRY XY gonadal dysgenesis Premature ovarian failure 7 SOX10 Waardenburg syndrome 4c Yemenite deaf-blind hypopigmentation syndrome 4...

using mutant fish have demonstrated that transcription factors such as kit, sox10, and mitf are important in controlling chromatophore differentiation. If...

MODY 3 MODY 5 SF1 SRY XY gonadal dysgenesis Premature ovarian failure 7 SOX10 Waardenburg syndrome 4c Yemenite deaf-blind hypopigmentation syndrome 4...

about 50% of cases. No reactivity occurs with other tumor markers such as SOX10, myogenin, estrogen receptor, progesterone receptor, or keratins. Genetic...

DDX17 KDELR3 KCNJ4 CSNK1E TMEM184B MAFF MAFF PLA2G6 BAIAP2L2 SLC16A8 PICK1 SOX10 POLR2F C22orf23 MICALL1 EIF3L ANKRD54 GALR3 GCAT H1F0 TRIOBP NOL12 LGALS1...

signaling pathways and dysfunction of transcriptional factors like KNOX20, SOX10 and EGR2. PMP22 has been found to interact with several different factors...

microphthalmia associated transcription factor (also known as MITF) as well as SOX10 genes. Type 2D is distinguished from other types through the absence of...

in pemphigus List of verrucous carcinoma subtypes Nat Pernick. "Stains - SOX10". Pathology Outlines. Topic Completed: 1 February 2014. Revised: 20 September...

suggests the location of FAM227A may be linked to a central regulator, SOX10, which is involved in the maturation of neural crest derivatives. Gene deletion...

(TAATCAATTA). Interaction of PAX3 with other transcription factors (such as SOX10) or chromatin factors (such as PAX3/7BP) enables synergistic activation...

consisted majorly of "mutations in the ENDRB or END3 gene", along "with [some] SOX10 mutations". Therefore, the researchers confirmed that ABCD syndrome was...

expression of various other genes important for neural crest induction (pax3, sox10, and foxd3). It is unclear however, if the loss of these neural crest specifiers...

SOX21 SoxC: SOX4, SOX11, SOX12 SoxD: SOX5, SOX6, SOX13 SoxE: SOX8, SOX9, SOX10 SoxF: SOX7, SOX17, SOX18 SoxG: SOX15 SoxH: SOX30 Body plan Evolutionary...

from neural crest cells to Schwann cell precursors is characterized by Sox10 and generally occurs around embryonic day 12-13 in rats. Schwann cell precursors...

IL17RD 3p14.3 Congenital hearing loss. Autosomal recessive 2, 2-5 611584 SOX10 SOX10 22q13.1 Congenital hearing loss. Waardenburg syndrome Autosomal dominant...